Cardiovascular Diseases

818 trials 341 recruiting

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Withdrawal of Pharmacological Treatment in Patients Responding to Cardiac Resynchronization Therapy: (REMOVE) Ended

2023-504946-70-00 Heart Failure 6 2021-12-01
A research study to find out whether a medicine called inclisiran helps to prevent cardiovascular death, heart attacks or strokes in people … Ended

2024-510735-21-00 Atherosclerotic cardiovascular disease (ASCVD) 5 2021-11-26
Randomized clinical trial assessing the value of Beta-Blockers and Antiplatelet Agents in patients with Spontaneous Coronary Artery Dissecti… Ended

2024-516039-28-00 Spontaneous Coronary Artery Dissection. 6 2021-09-28
ZEUS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With Cardiovascular Disease, Chronic Kidney Disease … Ended

2023-506926-35-00 Atherosclerotic cardiovascular disease, chronic kidney 5 2021-09-24
The assessment of cysteinyl leukotriene receptor antagonist role in inhibition of atherosclerosis, proliferation and its influence on endoth… Ended

2024-511894-32-00 Ischemia of the lower limbs in the course of obstructiv 5 2021-08-19
PEITHO-3 - A reduced dose of thrombolytic treatment for patients with intermediate high-risk acute pulmonary embolism: a randomized controll… Ended

2024-511321-54-00 intermediate-high-risk acute pulmonary embolism 5 2021-08-04
Hydrocorticose and vasopressin in post-resuscitation syndrome Ended

2024-516373-77-00 Adult cardiac arrest patients with sustained ROSC and h 5 2021-07-18
"Clinical Study of Inhaled GB002 for the Treatment of WHO Group 1 Pulmonary Arterial Hypertension (PAH)" Ended

2024-516754-22-00 Pulmonary Arterial Hypertension (PAH) 4 2021-07-14
The Nordic Aortic Valve Intervention Trial 4 (NOTION-4) Ended

2024-518547-38-00 Patients who have undergone successful transcatheter bi 6 2021-05-12
A study to compare how safe and well tolerated study drug Abelacimab (MAA868) is compared to another drug called Rivaroxaban in patients wit… Ended

2023-509066-38-00 Atrial Fibrillation 4 2021-04-16
Effect of impact of PCSK9 inhibitor on coronary microvascular dysfunction in patients with atherosclerotic cardiovascular disease needing co… Ended

2024-519012-14-00 atherosclerotic cardiovascular disease 4 2020-09-15
PACIFICA: A Phase 3 Study of Pacritinib in Patients with Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thro… Ended

2024-515953-52-00 Post-Essential Thrombocythaemia Myelofibrosis 5 2020-07-24
A Phase 3 study to compare long-term efficacy and safety of macitentan 75 mg versus 10 mg in Pulmonary Arterial Hypertension. Ended

2024-515669-32-00 Pulmonary arterial hypertension 5 2020-06-30
A global trial to determine the effectiveness and safety of ION-682884 in patients with Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-… Ended

2024-514434-20-00 Transthyretin-Mediated Amyloid Cardiomyopathy (ATTR-CM) 5 2020-06-29
A Study to Evaluate Vutrisiran in Patients with Transthyretin Amyloidosis with Cardiomyopathy Ended

2024-518318-25-00 Transthyretin Amyloidosis with Cardiomyopathy (ATTR Amy 5 2020-06-24
A multicenter trial assessing the impact of lipoprotein (a) lowering with pelacarsen (TQJ230) on major cardiovascular events in patients wit… Ended

2023-508292-37-00 Cardiovascular Disease 5 2020-03-06
The TARGET BP I Ended

2024-512525-83-00 Hypertension 5 2020-01-07
An open-label extension (OLE) study to evaluate the long-term safety and efficacy of ralinepag in patients with pulmonary arterial hypertens… Ended

2023-509305-68-00 Pulmonary arterial hypertension (PAH) 5 2019-05-16
Dual antiplatelet therapy with ticagrelor and acetylsalicylic acid (ASA) vs. ASA only after isolated coronary artery bypass grafting in pati… Ended

2023-508551-40-00 Coronary artery multi-vessel disease and left main sten 6 2018-06-08
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction SPIRRIT-HFpEF Ended

2024-517448-79-00 Heart failure with preserved ejection fraction 5 2017-11-23
Riociguat for treatment of PAH in children from 6 to less than 18 years old Ended

2023-503536-40-00 Pulmonary arterial hypertension (PAH) 5 2016-02-23
Corticotrophin Releasing Factor 2 Agonist For the Treatment of Worsening Heart Failure (WHF) – The CRAFT-WHF Study Halted

2024-518951-52-00 Worsening Heart Failure 4 2025-11-12
A phase 3, randomised, double-blind, placebo-controlled, parallel-arm efficacy trial of Imatinib in acute ischaemic stroke Halted

2023-506178-11-00 Acute ischemic stroke 5 2025-11-11
Public title :A Phase 1b/2a trial to evaluate Invobenitug also known as Procizumab (PCZ; AK1967) in critical cardiovascular care. Halted

2024-518450-16-00 Cardiogenic shock due to Acute Coronary Syndrome, cardi 9 2025-06-13