Digestive System Diseases

633 trials 301 recruiting

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OV-PRIME-R (Oncolytic Virotherapy to enhance PReoperative IMmunotherapy Efficacy in patients with proficient mismatch repair (pMMR) Rectal c… Pending

2025-524375-23-00 Rectal cancer with proficient mismatch repair (pMMR) 3
PRODIGE 104 – NEOPREDICT A multicenter phase II trial using transcriptomic signatures to personalize neoadjuvant chemotherapy for patients … Pending

2024-519753-11-00 Resectable borderline pancreatic adenocarcinoma 4
Optimal Duration of Antibiotic Therapy in Drained Pyogenic Liver Abscess: 3 weeks versus 6 weeks, a non-inferiority trial Pending

2025-520940-14-00 Pyogenic liver abscess 6
“Study of pain syndrome and clinical-biochemical parameters in children aged 7 to 18 years in cases of non-surgical treatment of uncomplicat… Pending

2025-520964-16-00 uncomplicated acute appendicitis 11
A Phase 1 Study of AIR-001 in Adults with AATD. Pending

2025-523558-14-00 Alpha-1 Antitrypsin Deficiency 1
PREDICTION OF COMPLICATIONS IN PATIENTS UNDERGOING SURGICAL TREATMENT OF HEPATIC TUMORS Pending

2025-524477-17-00 Hepatic tumor 6
ATLAS trial Pending

2024-517233-40-00 Perianal abscess 6
Fecal microbiota transplantation in patients receiving infliximab and vedolizumab for ulcerative colitis: A randomized controlled trial Pending

2024-520373-12-00 Ulcerative Colitis, Crohn´s disease 6
Oral Antibiotic Outpatient Therapy vs. Placebo in the Treatment of Uncomplicated Acute Appendicitis Pending

2023-506213-21-00 Uncomplicated acute appendicitis 6
Comparison of azathioprine to methotrexate in combination therapy with adalimumab in Crohn’s Disease: an open-label randomized controlled tr… Pending

2024-514633-38-00 Crohn’s Disease 5
A study to evaluate the safety and tolerability of single ascending doses of AGMB-101 in healthy participants (Part A) and patients with liv… Pending

2024-515074-26-00 liver cirrhosis 1
A double blinded, balanced, randomized, two-treatment, four-period, two-sequence, single-dose, crossover fully replicate bioequivalence stud… Pending

2025-521598-16-00 ulcerative colitis 2
The efficacy of oral vancomycin therapy in managing different phenotypes of paediatric inflammatory bowel diseases by correlating treatment … Pending

2025-524543-12-00 Ulcerative colitis 4
Fibroblast markers to tackle fibrosis in immune-mediated inflammatory diseases Pending

2025-522834-30-01 Idiopathic inflammatory myopathy (IIM) 4
OPTIMAL CARE WITH GUSELKUMAB IN CROHN’S DISEASE Pending

2025-524573-16-00 Crohn's disease 6
DIMREATOX study - Reduction in digestive absorption of toxic substances by combined digestive decontamination in intensive care - randomized… Pending

2024-518739-12-00 Major patients intoxicated by functional toxicant(s), h 4
Ursodeoxycolic acid for the prevention of relapsing complications after gallstone acute pancreatitis, a double-blind multicenter randomized-… Pending

2024-518237-28-00 recurrence of acute biliary pancreatitis 6
Impact of early proactive therapeutic drug monitoring on the durability and efficacy of infliximab therapy in pediatric inflammatory bowel d… Pending

2024-517759-11-00 Inflammatory Bowel Disease 6
Immunosuppressant Discontinuation in Elderly patients with ulcerative colitis And long-term remission Pending

2025-524675-23-00 Ulcerative Colitis 6
Perioperative Therapy with Durvalumab Plus Tremelimumab for Patients with Resectable Hepatocellular Carcinoma (HCC) - A Phase II Trial (NEOT… Pending

2023-508863-59-01 Resectable Hepatocellular Carcinoma 4
Efficacy of combined treatment by autologous cell therapy and percutaneous transluminal angioplasty (PTA) versus the treatment by isolated P… Pending

2024-512873-29-00 chronic limb-threatening ischemia 4
IMPACT OF ANTI-TNF, VEDOLIZUMAB AND TOFACITINIB ON AORTIC STIFFNESS, CAROTID INTIMA-MEDIA THICKNESS AND CARDIOVASCULAR RISK OF PATIENTS WIT… Pending

2024-517314-15-00 ulcerative colitis 11
Efficacy of the use of neoadjuvant with/without hyperthermic intraperitoneal chemotherapy in the treatment of locally advanced colon cancer Pending

2025-520471-29-00 Locally advanced adenocarcinoma of the colon and upper 5
Debut of Ulcerative Colitis: selective Top-down strategy - the DUCT trial Pending

2024-519891-17-00 Ulcerative colitis 4