Digestive System Diseases

633 trials 301 recruiting

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Personalized Vitamin D Supplementation for Reducing or Preventing Fatigue and Enhancing Quality of Life of Patients with Colorectal Tumor: R… Ended

2024-515420-37-01 Fatigue in patients with colorectal cancer (CRC) (ICD c 5 2020-09-28
A dose-esalation phase I/II study in patients with RAS-mutated metastatic colorectal cancer to investigate safety and clinical actvitiy of t… Ended

2023-509732-25-00 metastatic colorectal cancer with a proven RAS mutation 7 2020-07-31
A Long-term Safety Study of a Second Treatment with Darvadstrocel for Treating Complex Perianal Fistulas in Adults with Crohn's Disease Ended

2022-503014-23-00 Perianal fistulising Crohn´s disease 6 2020-06-03
Double-blinded (treatment group unknown to physician and patient), randomised (treatment group allocated by chance) phase II trial on the ef… Ended

2023-507897-42-00 Prevention of oesophageal strictures in adult patients 4 2020-05-12
This trial will evaluate the safety and efficacy of HepaStem compared to placebo in patients with a cirrhotic liver condition called Acute o… Ended

2022-500252-28-00 Cirrhotic patients who are hospitalized for Acute on ch 4 2019-12-17
Botulinum toxin (BOTOX®) to prevent post-operative pancreatic fistula in patients who undergo distal pancreatectomy Ended

2024-517267-23-00 postoperative pancreatic fistulas 7 2019-11-11
A study to learn about the effects and safety of obeticholic acid in combination with bezafibrate in participants with primary biliary chola… Ended

2024-513762-18-00 Primary Biliary Cholangitis (PBC) 4 2019-09-20
Buspirone for weak or absent esophageal peristalsis Ended

2024-516667-91-00 ineffective motility or absent peristalsis 6 2019-09-10
Treatment of bowel dysfunction after surgery for rectal cancer using transanal irrigation or laxatives Ended

2024-519492-25-01 Low Anterior Resection Syndrome 11 2019-07-24
EASE SBS 2 (Evaluation of the efficacy and safety of Glepaglutide in the treatment of short bowel syndrome) (SBS) Ended

2024-513374-22-00 Short Bowel Syndrome 5 2019-04-30
Acute-On-Chronic Liver Failure (ACLF) at High Risk of Hospital Mortality Ended

2022-502187-20-00 Subjects with cirrhosis with ACLF-1b, ACLF-2, or ACLF-3 5 2019-04-11
A Study of the Efficacy and Safety of Golimumab in Pediatric Participants with Moderately to Severely Active Ulcerative Colitis Ended

2023-507142-83-00 Ulcerative Colitis 5 2019-01-09
Multicenter Extension Study of Oral Ozanimod in patients with Moderately to Severely Active Crohn's Disease Ended

2024-511553-22-00 Moderately to Severely Active Crohn's Disease 5 2018-10-05
Multicenter Study of Oral Ozanimod as Maintenance Therapy in patients with Moderately to Severely Active Crohn's Disease Ended

2023-510426-33-00 Moderately to Severely Active Crohn's Disease 5 2018-09-27
FFCD 1605- OPTIPRIME: A phase II study evaluating FOLFOX + panitumumab according to a ‘stop-and-go’ strategy with a reintroduction loop afte… Ended

2024-518740-20-00 metastatic colorectal adenocarcinoma 4 2018-04-26
Treatment of refractory Crohn's disease lesions by local injection of mesenchymal stem cells Ended

2024-514033-37-00 Crohn's Disease 9 2018-03-01
An extension study to investigate how safe Vedolizumab is in child patients with Ulcerative Colitis or Crohn's Disease Ended

2023-507766-35-00 Ulcerative Colitis or Crohn's Disease 4 2018-01-09
Double-blind, randomized, placebo-controlled, phase III study comparing norursodeoxycholic acid capsules with placebo in the treatment of pr… Ended

2023-510200-42-00 primary sclerosing cholangitis (PSC) 5 2017-12-06
Ramucirumab plus Irinotecan / Leucovorin / 5-FU versus Ramucirumab plus Paclitaxel in patients with advanced or metastatic adenocarcinoma of… Ended

2024-512934-14-00 advanced or metastatic adenocarcinoma of the stomach or 5 2016-11-07
A Study to Evaluate the Long-Term Efficacy, Safety, and Tolerability of Repeated Administration of Upadacitinib (ABT-494) in Participants Wi… Ended

2024-510727-19-00 Crohn's Disease (CD) 4 2016-10-11
A Multi-Center, Open-Label Study of Adalimumab to Evaluate Long-Term Safety and Tolerability of Repeated Administration of Adalimumab in Ped… Ended

2023-504711-32-00 Ulcerative Colitis 5 2015-11-24
The purpose of this study is to determine whether long-term RPC1063 is safe and effective in the treatment of ulcerative colitis (UC) Ended

2024-514815-92-00 Ulcerative colitis 5 2015-07-16
Open-label non-randomized multicentric phase 2 study evaluating the combination of bemarituzumab + FLOT chemotherapy in perioperative settin… Ended

2024-514078-29-00 gastric and gastro-oesophageal junction adenocarcinomas 4
Simvastatin in the Prevention of Recurrent Pancreatitis, a Triple Blind, Randomized Controlled Trial. Ended

2024-513188-17-03 Recurrent pancreatitis 6