Eye Diseases

237 trials 74 recruiting

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IDE196 (DAROVASERTIB) IN COMBINATION WITH CRIZOTINIB VERSUS INVESTIGATOR’S CHOICE OF TREATMENT AS FIRST-LINE THERAPY IN HLA-A2 NEGATIVE META… Not authorised

2023-506686-66-00 HLA-A2 negative metastatic uveal melanoma 10
Phase I, single and multiple ascending dose, randomized, double-blind, placebo-controlled, parallel-group clinical trial to evaluate the saf… Not authorised

2024-518758-18-00 Diabetic retinopathy. 1
Randomized clinical trial to evaluate the use of PRGF eye drops in patients with dry eye disease Not authorised

2023-507357-15-00 Dry Eye Disease 6
A Two-Year Double-masked, Randomized, Sham-Controlled Study to Evaluate the Efficacy, Safety and Tolerability of Ultevursen in Subjects with… Not authorised

2024-515199-10-00 Retinitis Pigmentosa 4
"A Clinical Study to Evaluate the Effectiveness of Beltavac® with polymerized extract of grass pollen mixture in allergic rhinoconjunctivit… Not authorised

2025-520581-22-00 Allergic rhinoconjunctivitis caused due to exposure to 4
"A Clinical Study to Evaluate the Effectiveness of Beltavac® with polymerized extract of grass pollen mixture in allergic rhinoconjunctivit… Not authorised

2023-510033-28-00 allergic rhinoconjunctivitis caused due to exposure to 4
Treating discharge and discomfort of eye prosthesis: a comparison between vitamin A ointment, anti-inflammatory eye drops and standard eye d… Not authorised

2023-504451-27-00 Chronic mucopurulent discharge and/or discomfort of the 6
A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With X-linked Retinitis Pig… Not authorised

2024-511181-36-00 X-linked retinitis pigmentosa (XLRP) 5
A prospective, observer-blind, randomized clinical trial to investigate and compare the clinical efficacy of Chloroprocaine 3% gel and Oxybu… Not authorised

2023-504477-21-00 male/female outpatients, aged 0-17 years scheduled to u 5
SYMBOL CLINICAL : Treatment of severe ocular chemical burns by subconjunctival injection of allogeneic mesenchymal stem cells: a multicentre… Pending

2023-509713-37-00 Patient with severe eye chemical burns 4
An efficacy and safety study of cenegermin ophthalmic solution compared with vehicle in the treatment of PCED Pending

2025-523443-35-00 Persistent Corneal Epithelial Defect (PCED) 5
Systemic nitrates in refractory normal tension glaucoma Pending

2025-522059-24-00 Normal tension glaucoma 6
Evaluation of a therapeutic de-eScalation strategy based on therapeutic drug MOnitOring in chronic non-infectious uveitis Treated witH adali… Pending

2023-509733-39-00 noninfectious uveitis 6
Antisense Oligonucleotide Eye Drops against IRS-1 to Optimize Pretransplant Lymphangio-regression Prior to High-Risk Keratoplasty (Olisens-P… Pending

2025-522099-10-00 Pathologically prevascularized corneas due to herpetic 4
Pilot study of the efficacy of nicotinamide (vitamin B3) in Leber's hereditary optic neuropathy - NICOLHON Pending

2025-524343-13-00 Leber's Hereditary Optic Neuropathy 4
Impact Of Upadacitinib On The Frequency Of Acute Recurrent Anterior Uveitis In Patients With Axial Spondyloarthritis Pending

2025-522118-21-00 Acute Anterior Uveitis 6
Clinical Trial to evaluate the efficacy and safety of cell therapy for dry eye disease in Graft-versus-Host Disease (GvHD) context. Pending

2024-519772-10-00 Dry eye disease in patients with Graft versus Host dise 4
Safety and efficacy of T10430 eye drops in controlling paediatric myopia progression Pending

2025-521563-13-01 Paediatric myopia 4
A Study to Compare the Effectiveness and Safety of T1695 (0.1% Tacrolimus) Versus Ciclosporin in Participants With Moderate to Severe Vernal… Pending

2025-521567-12-00 Vernal Keratoconjunctivitis (VKC) 4
Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) with Atorvastatin (ATORGO) Pending

2023-504654-35-00 Graves Ofthalmopathy 4
Safety of stem cells in treatmemt of retinal diseases. Pending

2023-503573-38-00 Retinal degenerative diseases 3
A randomized double-masked, multicenter, 3 arm pivotal Phase 2/3 study to evaluate the efficacy and safety of intravitreal (IVT) EYE201/MK-8… Pending

2025-524575-22-00 Neovascular age-related macular degeneration (NVAMD) 10
Long-term Follow-Up Study of RGX-314 and Fellow Eye Substudy Pending

2023-505750-17-00 Neovascular age-related macular degeneration 4
An Open-label, Multicenter Trial to Assess Safety and Efficacy of a Subretinal Administration of AAVB-039 Pending

2025-522207-15-01 Stargardt Disease (STGD1) 7