Hemic and Lymphatic Diseases

593 trials 238 recruiting

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Research study investigating how well NDec works in people with sickle cell disease Ended

2023-508506-22-00 Sickle cell disease 4 2022-09-22
Study in Paediatrics with HypEREosinophilic syndrome (SPHERE) Ended

2023-510110-36-00 Hypereosinophilic syndrome (HES) 5 2022-07-11
Study of four-factor prothrombin complex concentrate, OCTAPLEX, in patients with acute major bleeding on direct oral anticoagulant (DOAC) th… Ended

2024-515485-14-00 Acute major bleeding in patients receiving DOAC therapy 5 2022-07-07
Efficacy and safety of iptacopan (LNP023) in adult patients with atypical hemolytic uremic syndrome naïve to complement inhibitor therapy Ended

2023-508840-22-00 Atypical hemolytic uremic syndrome 5 2022-06-27
Safety and Preliminary Efficacy Assessment of AZD7789 in Patients With Relapsed or Refractory Classical Hodgkin Lymphoma Ended

2022-502773-41-00 Relapsed/Refractory Classical Hodgkin Lymphoma 9 2022-06-16
A Study to Assess Safety, Tolerability and Preliminary efficacy of Bexmarilimab in Combination with Standard of Care in Patients with Hemato… Ended

2024-517444-64-00 Chronic Myelomonocytic Leukemia 9 2022-05-30
LAMSA2020: “A phase II randomized study to assess the efficacy on outcome of Venetoclax combined with Cytarabine versus Idarubicin combined… Ended

2022-502392-37-00 elderly patients (> = 60 years) with Acute Myeloid Leuk 4 2022-05-25
Treatment of non severe Hemophagocytosis Lymphohistiocytosis with ITACITINIB a Phase II prospective trial Ended

2024-513173-44-00 Adults patients having non severe HLH 4 2022-05-03
Tamibarotene/Venetoclax/Azacitidine in Previously Untreated Patients Selected for RARA-positive AML (SELECT-AML-1) Ended

2024-510939-21-00 RARA-positive acute myeloid leukemia 4 2022-04-01
HEMolyse and Organ damage imPROvement in sickle cell disease by VoxElotor Ended

2024-513096-41-00 sickle cell disease 4 2022-03-24
FORMAT Study : Use of fibrinogen in the treatment of bleeding in thrombopenic patients after intensive chemotherapy refractory to platelet t… Ended

2024-516494-73-00 Hematological malignancy 4 2022-02-10
Study to evaluate Pegcetacoplan in patients with TA-TMA after hematopoietic stem cell transplantation Ended

2023-510443-37-00 Transplant-associated Thrombotic Microangiopathy (TA TM 4 2022-01-26
A phase II trial of belimumab in combination with rituximab/venetoclax in patients with refractory or relapsed chronic lymphocytic leukemia Ended

2024-511474-68-00 refractory or relapsed chronic lymphocytic leukemia 4 2022-01-19
FAMODREP : Interest of Famotidine in Reducing Endothelial Expression of P-selectin in Children With Sickle Cell Disease: Pilot Study, Single… Ended

2022-502144-12-00 Sickle Cell Disease 6 2022-01-12
A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Crovalimab as Adjunct Treatment in Prevention of Vaso-Oc… Ended

2022-502542-28-00 Sickle Cell Disease 4 2021-12-06
A Randomized, Open-Label, Phase 1-2 Study of ASTX727 Low Dose (ASTX727 LD) Extended Schedule in Subjects with Lower Risk (IPSS Low or Interm… Ended

2024-516296-32-00 Myelodysplastic Syndromes (MDS) 3 2021-11-11
TRANEX Ended

2024-513573-49-00 Burn injury 6 2021-11-03
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo-Controlled, Efficacy and Safety Study of Birtamimab Plus Standard of Care vs. Plac… Ended

2024-511066-36-00 Light Chain (AL) Amyloidosis 5 2021-10-13
Efficacy and safety of obinutuzumab versus rituximab in combination with chemotherapy for adult patients with newly diagnosed CD20-positive … Ended

2024-517389-40-00 acute lymphoblastic leukemia 4 2021-10-06
Therapeutic strategy driven by residual disease for CARCIK-CD19 in patients with relapsed/refractory B cell precursor Acute Lymphoblastic Le… Ended

2024-519394-19-00 B cell precursor Acute Lymphoblastic Leukemia 4 2021-09-22
A continuation study to evaluate the prophylactic and on demand treatment of congenital Thrombotic Thrombocytopenic Purpura (cTTP) with the … Ended

2024-513839-24-00 Congenital Thrombotic thrombocytopenic purpura (cTTP) 5 2021-09-07
An open-label, long-term, safety and tolerability study of SAR445088 in participants with cold agglutinin disease previously treated with SA… Ended

2023-510210-68-00 Autoimmune haemolytic anaemia 3 2021-05-26
VEN-DEC GITMO Study Ended

2024-518792-54-00 Acute Myeloid Leukemia (AML) 4 2021-05-13
Polatuzumab vedotin plus rituximab, ifosfamide, carboplatin and etoposide (Pola-R-ICE) versus R-ICE alone in second line treatment of diffus… Ended

2023-508259-38-00 Adult patients with relapsed or primary refractory DLBC 5 2021-04-29