Hemic and Lymphatic Diseases

593 trials 238 recruiting

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BiCAR Therapy - A Phase II Trial Evaluating Glofitamab, a Bispecific CD3xCD20 Antibody for Relapse/Refractory Lymphomas after CAR T-cells th… Ended

2023-508301-25-00 Relapse/Refractory Lymphomas 4 2021-03-26
A Phase 3, Open-label, Single Arm, Multicenter Study of Ravulizumab in Addition to Best Supportive Care in Pediatric Participants (from 1 mo… Ended

2023-507850-33-00 Hematopoietic stem cell transplant-associated thromboti 5 2021-02-05
A Clinical Trial to Test the Safety, Effect, and Activity of Rilzabrutinib (PRN1008) in Adult and Adolescent Patients with Persistent or Chr… Ended

2023-509401-71-00 Immune Thrombocytopenia (ITP) 5 2021-02-05
Randomized trial evaluating adapted chemotherapy in patients with squamous carcinoma Ended

2024-512456-38-00 locally advanced squamous cell carcinoma 4 2021-02-04
An Open-Label Phase I/II Study of Relatlimab (BMS-986016) with Nivolumab (BMS-936558) in Combination with 5-Azacytidine for Relapsed/Refract… Ended

2024-514948-89-00 Acute Myeloid Leukemia 9 2021-01-27
A Phase I/IIb extension study assessing the long-term safety and efficacy of a gene therapy (AAV5-hFIX) previously administered to adult pat… Ended

2024-512603-39-00 Haemophilia B 7 2021-01-08
A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of Ravulizumab in Adult and Adolescent Participants who have Thro… Ended

2023-510107-22-00 Hematopoietic stem cell transplant-associated thromboti 5 2020-10-27
ISKPD-IFM2018-03-Multicenter Open label Phase 2 study of Isatuximab plus Pomalidomide and Dexamethasone with Carfilzomib in Relapsed or Refr… Ended

2024-516670-29-00 Multiple Myeloma 4 2020-09-15
A Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of emicizumab in patients with mild or moderate hemophilia A… Ended

2023-506610-52-00 Mild or moderate hemophilia A without FVIII inhibitors 5 2020-06-24
TOPical sirolimus in linGUal microkystic lymphatic malformation Ended

2024-515955-39-01 Lingual microcystic lymphatic malformations (LMLMs) are 4 2020-02-04
Phase 1 Study of UniCAR02-T-CD123 in Patients With Selected CD123 Positive Hematologic Malignancies Ended

2024-515827-12-00 Acute Myeloid Leukemia (AML) 1 2020-01-28
Gene Therapy for Pyruvate Kinase Deficiency (PKD): A Phase I Clinical Trial to Evaluate the Safety of the Infusion of Autologous CD34+ Cells… Ended

2024-511520-13-00 Inherited metabolic disorder of the enzyme pyruvate kin 3 2019-11-04
An Early Phase Study with the Drug LOXO-305 in Patients with Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL… Ended

2023-509270-37-00 Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma 7 2019-10-10
A Clinical Trial Evaluating the Safety and Efficacy of Venetoclax in Combination with Atezolizumab and Obinutuzumab in Richter Transformatio… Ended

2024-516675-32-00 Richter syndrome of chronic lymphocytic leukemia 4 2019-10-08
MRD-guided treatment with pembrolizumab and azacitidine in NPM1mut AML patients with an imminent hematological relapse Ended

2024-513956-14-00 Acute myeloid leukemia 4 2019-09-16
A study comparing current standard therapies with fedratinib for the treatment of myelofibrosis (either diagnosed alone or after polycythemi… Ended

2024-511972-33-00 Primary myelofibrosis, post-polycythemia vera myelofibr 5 2019-08-05
Expanded access program for mepolizumab in subjects with hypereosinophilic syndrome. Ended

2024-515247-28-00 Hypereosinophilic Syndrome 5 2019-03-29
A phase III trial investigating a gene therapy (AAV-hFIXco-Padua, AMT061), in adult patients with severe or moderately severe haemophilia B,… Ended

2024-510738-42-00 Haemophilia B 5 2018-12-03
Rituximab, bendamustine and cytarabine followed by venetoclax (V-RBAC) in high-risk elderly patients with mantle cell lymphoma (MCL) Ended

2024-511533-35-00 Mantle Cell Lymphoma 4 2018-09-03
Blinatumomab added to prephase and consolidation therapy in precursor B-acute lymphoblastic leukemia in adults. Ended

2024-511050-44-00 Precursor B-acute lymphoblastic leukemia 4 2018-05-16
A RANDOMIZED TRIAL TESTING EARLY VERSUS LATE ONSET OF EPO ALFA TREATMENT IN LOWER RISK MDS WITH NON RBC TRANSFUSION DEPENDENT ANEMIA AND WI… Ended

2024-515356-21-00 Adult subject (18 years of age older) with low or inter 5 2018-04-17
A Study of Rilzabrutinib in Adult Patients With Immune Thrombocytopenia (ITP) Ended

2023-509397-39-00 Immune Thrombocytopenia 9 2018-03-20
A prospective, multicenter, phase-II trial of ibrutinib plus venetoclax in physically fit patients with creatinine clearance ≥ 30 ml/min who… Ended

2023-510557-42-00 chronic lymphocytic leukemia 4 2017-07-10
A study of Ibrutinib in combination with Rituximab versus Placebo in combination with Rituximab in treatment of patients with Follicular Lym… Ended

2023-507271-21-00 Follicular Lymphoma 5 2017-04-11