Immune System Diseases

905 trials 381 recruiting

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Tofacitinib in early active axial spondyloarthritis: a prospective, randomized, double-blind, placebo-controlled multicentre study - FASTLAN… Ended

2023-505050-18-00 Axial spondyloarthritis 6 2023-11-16
Orismilast for the treatment of moderate to severe ulcerative colitis Ended

2022-502763-37-02 ulcerative colitis 4 2023-11-16
A study to test the efficacy and safety of SAR442970 in adults with hidradenitis suppurativa Ended

2022-502370-17-00 Hidradenitis suppurativa 4 2023-11-14
Phase II-III study to assess the efficacy and safety of sublingual immunotherapy in patients suffering from grass pollen allergy Ended

2023-505880-35-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 10 2023-11-10
An Open-Label, Phase 2, Safety, and Efficacy Study of Ruxolitinib Cream in Participants With Genital Vitiligo Ended

2023-503737-22-00 Nonsegmental vitiligo with genital involvement 4 2023-11-08
A trial to investigate the effect of acalabrutinib on skin prick test wheal size in adults with grass pollen allergy Ended

2023-505783-11-00 grass pollen allergy 3 2023-10-26
A Study of Zetomipzomib (KZR-616) in Patients With Active Lupus Nephritis (PALIZADE) Ended

2022-502227-22-00 Autoimmune disease 4 2023-10-25
A study to investigate JNJ-80202135 (nipocalimab) delivered subcutaneously via prefilled syringe autoinjector and via normal syringe Ended

2023-504280-16-00 Healthy Volunteers 3 2023-10-17
Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy (EXPA… Ended

2023-503830-27-00 Large B-Cell Lymphoma (LBCL) 4 2023-10-17
A study to investigate the effects of multiple doses of obefazimod on a combined oral contraceptive (ethinyl estradiol/drospirenone) in hea… Ended

2023-505297-15-00 Healthy female participants of childbearing potential. 3 2023-10-10
A multicenter, single arm, open-label trial to evaluate efficacy and safety of oral, twice daily iptacopan in adult PNH patients who have Hb… Ended

2022-502148-10-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 5 2023-10-10
Therapeutic Use of Tadekinig Alfa in NLRC4 Mutation and XIAP Deficiency as Open Label Extension Ended

2023-504534-21-00 18 driven monogenic autoinflammatory conditions: NLRC4 5 2023-10-09
A Study to Evaluate the Safety and Tolerability of JNJ-77730614 When Given as Single and Multiple Doses to Healthy Participants to Assess Ho… Ended

2023-505684-36-00 Healthy Volunteers 1 2023-10-09
A Phase I study to evaluate the pharmacokinetics, safety, and tolerability of multiple oral doses of obefazimod in patients with mild and mo… Ended

2023-505299-31-00 Ulcerative colitis and rheumatoid a1thritis 3 2023-10-09
A Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Prurigo Nodularis Ended

2022-501621-20-00 Prurigo Nodularis 5 2023-10-02
Safety and Efficacy of ALLO-501A Anti-CD19 Allogeneic CAR T Cells in Adults With Relapsed/Refractory Large B Cell Lymphoma (ALPHA2) Ended

2022-501927-25-00 Large B-Cell Lymphoma (LBCL) 4 2023-09-29
A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis Ended

2022-502888-38-00 Atopic dermatitis 4 2023-09-25
A Phase 3 Study of Obexelimab in Patients with Warm Autoimmune Hemolytic Anemia Ended

2022-501005-12-00 WARM AUTOIMMUNE HEMOLYTIC ANEMIA 5 2023-09-22
A Multi-national Phase IIIb Trial to Determine the Safety and Efficacy of STALORAL® Birch 300 IR in Children and Adolescents 5 to 17 Years o… Ended

2023-509833-38-00 Birch Pollen-induced Allergic Rhinoconjunctivitis 5 2023-09-20
Long-term extension study of ligelizumab in food allergy Ended

2022-502366-25-00 Food allergy 5 2023-09-11
Study of Leniolisib in Pediatric Patients (Aged 4 to 11 Years) with APDS (Activated Phosphoinositide 3-Kinase Delta Syndrome) Ended

2024-515489-15-00 Activated Phosphoinositide 3-Kinase Delta Syndrome 5 2023-09-06
A Study to Evaluate the Efficacy and Safety of Vixarelimab Compared with Placebo in Patients with Idiopathic Pulmonary Fibrosis and in Patie… Ended

2022-502828-42-00 Idiopathic Pulmonary Fibrosis 4 2023-09-01
A Study to Learn About the Study Medication Called Etrasimod Mini Tablets, Including Its Taste, When Mixed With Applesauce, Chocolate Puddin… Ended

2023-504411-32-00 immune-mediated inflammatory disorders, including ulcer 3 2023-08-23
PREPARE-iVAC Ended

2023-503894-39-00 kidney transplantation 11 2023-08-22