Immune System Diseases

905 trials 381 recruiting

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Phase 3 Study of Telitacicept in Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-2) Not authorised

2024-512716-21-00 Moderately to Severely Active Systemic Lupus Erythemato 5
A phase 2b, single-center, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of oral Ladarixin in associa… Not authorised

2025-524298-18-00 new-onset autoimmune type 1 diabetes 4
A study to find how well budoprutug (TNT119) works and how safe it is in participants with immune thrombocytopenia Not authorised

2024-519745-30-00 Immune Thrombocytopenia (ITP) 9
Drug Rediscovery for rare Immune Mediated Inflammatory Diseases (DRIMID) Not authorised

2022-502968-20-01 Idiopathic Inflammatory Myopathies 4
PRObiotic Therapy Examining Combinatorial Therapeutics in Multiple Sclerosis - phase II, multicenter, randomised, open-label clinical trial. Not authorised

2025-520955-10-00 Multiple sclerosis 4
A study to find how well budoprutug (TNT119) works and how safe it is in participants with Systemic Lupus Erythematosus Not authorised

2024-520385-57-00 Systemic Lupus Erythematosus 3
A PHASE III OPEN LABEL STUDY CONTROLLED BY VITAMIN D3 SUPPLEMENTATION AND THE DIFFERENCES BETWEEN YOUNG ADULTS AND SENIOR POPULATION Not authorised

2024-511889-36-01 Healthy population 5
A phase III, randomised, double-blind, multicentre study comparing the efficacy, safety, and immunogenicity of proposed tocilizumab biosimil… Not authorised

2022-501361-44-00 Adult patients of either gender with active moderate to 5
PHASE I/IIa CLINICAL TRIAL FOR THE TREATMENT OF GRAFT VERSUS HOST DISEASE WITH A NEW GENERATION OF MESENCHYMAL STROMAL CELLS ECTOPICALLY EXP… Not authorised

2025-523139-21-00 Patients who have developed acute GVHD refractory to co 9
Phase 3 Study Assessing Rocatinlimab (AMG 451) in Adolescent Subjects With Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Orbit) Not authorised

2022-501535-16-00 Atopic Dermatitis (AD) 5
Testing the safety and efficacy of combining biologic drugs in Rheumatoid and Psoriatic Arthritis Not authorised

2024-518011-19-00 Psoriatic Arthritis 4
Study analyzing the efficacy and safety of low-dose oral immunotherapy in children with severe allergy to cow's milk treated with Omalizumab… Pending

2023-503958-12-00 Severe IgE-mediated cow's milk allergy 4
A study to find how safe different doses of LFD-200 are and how it works in both healthy people and people with moderate to severe rheumato… Pending

2025-523409-13-00 Moderate to Severe Rheumatoid Arthritis 1
An autologous and antigen-specific cell-based therapy of vitamin D3-treated and myelin-derived peptide loaded tolerogenic dendritic cells in… Pending

2025-522040-40-01 Multiple Sclerosis 4
Allergen extract of Lepidoglyphus destructor. Study of the sensitivity and specificity of the diagnostic preparation in prick tests Pending

2025-523426-40-00 Allergy to Lepidoglyphus destructor 5
A study to investigate how well and safe a trial drug called AZD1163, administered as an injection, works in improving symptoms and inflamma… Pending

2025-522076-85-00 Rheumatoid arthritis 4
A Long-Term Extension Study to Evaluate the Safety and Efficacy of Ritlecitinib in Participants With Severe AA Who Have Completed Studies B7… Pending

2024-515439-31-00 Alopecia areata 5
Evaluation of Allergen Specific Vaccination of Dog Allergic Patients in Swedish Practice Pending

2024-517649-15-00 Allergic rhinitis due to dog allergy 6
A study to test whether different doses of BI 3000202 help people with systemic lupus erythematosus (SLE) Pending

2025-523488-39-00 Systemic lupus erythematosus 4
Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic Arthritis (SMART-JIA) Pending

2025-520923-25-00 Juvenile Idiopathic Arthritis 5
Dose determination study of Phleum pratense allergenic extract for immunotherapy treatment, administered via sublingual route, standardized … Pending

2025-522730-31-00 Allergic rhinitis/rhinoconjunctivitis caused by grass p 4
Randomized Open Label Trial Evaluating Efficacy and Safety of Intravenous Immunoglobulin (IVIg, Privigen) as Add-on to SoC Versus SoC Alone … Pending

2025-522756-97-00 COVID-19 and Severely Impaired B-cell Function 4
ESTIS trial: Early Stop of targeted Treatment in children with Systemic JIA. Pending

2024-518684-35-00 autoimmune disorders, joint disorders synonym: Still's 6
Clinical trial to assess the efficacy and safety of a vaccine for dust mite and Lepidoglyphus destructor allergy. Pending

2025-522771-28-00 Aetiological treatment of moderate-to-severe allergic r 5