Immune System Diseases

905 trials 381 recruiting

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Clinical trial to assess the efficacy and safety of a vaccine for dust mite and Blomia tropicalis allergy. Pending

2025-522773-12-00 Aetiological treatment of moderate-to-severe allergic r 5
A study to learn more about the amount of bimekizumab in the breast milk of women with chronic inflammatory conditions who are breastfeeding Pending

2024-518689-29-00 Hidradenitis suppurativa 3
A multiCenter phase I study of aUtologous CD19 CAR T cElls for therapy refractory chronic GvHD (CURE-cGvHD) Pending

2025-524468-40-00 chronic Graft-versus-Host-Disease (cGvHD) 3
Prophylactic Treatment of Graves Ophthalmopathy (GO) in Newly Diagnosed Graves' Disease (GD) with Atorvastatin (ATORGO) Pending

2023-504654-35-00 Graves Ofthalmopathy 4
efficacy and safety of the use of regulatory T cells in immune hyperactivation in patients with COVID-19 and/or acute respiratory distress s… Pending

2024-519799-25-00 immune hyperactivation in COVID-19 patients and/or acut 7
Crohn’s Head-to-Head Assessing Risankizumab Versus Guselkumab for One Year Pending

2025-521590-13-00 Moderately to Severely Active Crohn’s Disease 5
An Extension Study to Assess Long-Term Safety and Efficacy of Afimkibart in Participants with Rheumatoid Arthritis Pending

2025-523579-47-00 moderate to severe rheumatoid arthritis (RA) 4
Efficacy of certolizumab in women with unexplained recurrent implantation failure: a double-blind randomized controlled trial (CERTIFY) Pending

2024-511869-11-00 Adult women with recurrent implantation failures (RIF) 5
THRILL: Treat Hyperinflammation in child oncology study Pending

2025-524541-27-00 Hyperinflammation 4
Fibroblast markers to tackle fibrosis in immune-mediated inflammatory diseases Pending

2025-522834-30-01 Idiopathic inflammatory myopathy (IIM) 4
Supporting weak immune system during autoimmune therapy: testing Panzyga to prevent infections Pending

2025-522854-37-00 Prevention of a Major infection in patients with Hypoga 5
A maintenance study to investigate the efficacy and safety of duvakitug in participants with moderately to severely active Crohn’s disease Pending

2025-521037-86-00 Immune system diseases 5
Sublingual Birch Immunotherapy for Pollen-associated Food Allergy Pending

2025-523653-34-00 Pollen-associated Food Allergy 4
A maintenance study to investigate the efficacy and safety of duvakitug in participants with moderately to severely active ulcerative coliti… Pending

2025-521038-27-00 Immune system diseases 5
Clinical trial comparing the efficacy and safety of certolizumab pegol and belimumab in patients with moderate or severe activity of systemi… Pending

2024-517753-27-01 moderate or severe activity of systemic lupus erythemat 5
A Study to Evaluate the Treatment Outcomes of Subcutaneous Anifrolumab in Immunosuppressant-naïve and Biologic-naïve Systemic Lupus Erythema… Pending

2025-523670-17-00 Systemic lupus erythematosus 5
An Open Label, Single Arm, Phase I/II Clinical Study of Autologous CD4+ T-Cells Edited Ex-Vivo at the CD40LG Locus by CRISPR/Cas9 and IDLV-b… Pending

2025-524635-39-00 X-linked immunodeficiency with hyper-IgM type 1 (HIGM1) 7
Phase 1b study to assess the safety and tolerability of SR-878 in patients with rheumatoid arthritis Pending

2025-523678-17-00 rheumatoid arthritis 3
Impact of early proactive therapeutic drug monitoring on the durability and efficacy of infliximab therapy in pediatric inflammatory bowel d… Pending

2024-517759-11-00 Inflammatory Bowel Disease 6
CAALL-F01: a French protocol for the treatment of acute lymphoblastic leukemia (ALL) in children and adolescents Pending

2024-514243-29-01 This is a prospective, French, multicenter, open-label, 5
Clinical Study to Evaluate the Effects of Cevostamab in Patients with Lupus with or without Active Lupus Nephritis Pending

2025-522904-26-00 Systemic Lupus Erythematosus (SLE) With or Without Acti 3
Anti-CD 19 CAR-T cell therapy in patients with ANCA Vasculitis - the IDEAL trial Pending

2024-517303-36-00 ANCA-IgG-positive ANCA associated vasculitis 9
MUNC13.4 - A phase I/II Open Label non randomized study, monocentric, single arm, evaluating Safety and Efficacy of Gene Therapy of FHL 3 ca… Pending

2023-507334-24-00 Familial Hemophagocytic Lymphohistiocytosis (FHL) 1
A study to investigate the safety, pharmacokinetics, pharmacodynamics, and immunogenicity of a CD19/CD20 T-cell engager in participants with… Pending

2025-522932-15-00 Systemic Lupus Erythematosus 3