Immune System Diseases

905 trials 381 recruiting

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A Study of LY4005130 in Adult Participants With Non-Segmental Vitiligo Pending

2025-524726-18-00 Non-Segmental Vitiligo (NSV) 4
Ultimate dePletion of autoReactive b cells using Obinutuzumab from sjÖgren's syndrome affected Tissues study- UPROOT study Pending

2024-519884-16-00 Sjögren's syndrome 4
Comparative Efficacy of Nipocalimab and Efgartigimod in Myasthenia Gravis Study ID: 80202135MYG3002 EPIC Pending

2025-521130-28-00 generalized myasthenia gravis 5
Research into the effect of Obinutuzumab on the level of PLA2R antibodies in patients with membranous nephropathy. Pending

2025-521139-35-01 Primary membranous nephropathy 4
Grass/Olive Immunotherapy for Rhinitis and Asthma (GOES) Pending

2025-521709-42-00 Allergic rhinoconjunctivitis with or without asthma due 5
Tocilizumab Dose Optimization in Rheumatoid Arthritis Pending

2025-520513-30-00 Rheumatoid arthritis 6
RESET-Myositis: An Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Idiopathic Inflammatory Myopathy… Pending

2025-521145-24-01 Active Idiopathic Inflammatory Myopathy including derma 9
Evaluation of Glucocorticoids Plus Rituximab Compared to Glucocorticoids Plus Placebo for the Treatment of Patients With Newly-Diagnosed or … Pending

2024-516052-17-01 Patients with a diagnosis of IgAV according to Chapel H 10
IL-1β blockade to prevent Immunothrombosis in recipients of a Pancreatic Organ (ILIPO) Pending

2025-524834-24-00 diabetic patients pancreatic transplant 9
FAPI-PET for GPSD Pending

2024-511977-31-01 giant cell arteritis - polymyalgia rheumatica spectrum 4
Grass Immunotherapy for Rhinitis and Asthma (GIRA) Pending

2025-521736-10-00 Allergic rhinoconjunctivitis with or without controlled 5
A SINGLE-ARM, OPEN-LABEL, PHASE II STUDY TO DETERMINE THE SAFETY AND EFFICACY OF OBECABTAGENE AUTOLEUCEL (OBE-CEL) IN PARTICIPANTS WITH SEVE… Pending

2024-519941-32-00 Systemic Lupus Erythematosus with Active Lupus Nephriti 4
The use of [68Ga]Ga-FAPI PET/MRI in assessing disease activity in patients with Graves’ orbitopathy Pending

2025-521163-12-01 Graves' Orbitopathy 9
A study to test single and multiple doses of MER511 given to adults with Graves’ disease Pending

2025-523823-23-00 Graves’ disease 1
Venetoclax as treatment of acute graft-versus-host disease Pending

2025-520545-74-00 Acute graft-versus-host disease of the skin 4
A study to measure mirikizumab levels in breast milk of lactating participants receiving mirikizumab therapeutically for an approved indicat… Pending

2025-522362-78-00 severely active ulcerative colitis (US) and CD (Crohn’s 6
A double-blind, randomised, placebo-controlled, first-in-human (FIH) Phase I/IIa, multi-centre trial to assess safety, tolerability, and imm… Pending

2024-515627-10-00 generalised myasthenia gravis 7
Intralymphatic Allergen Immunotherapy (ILIT) in grass pollen allergy: a randomized controlled trial Pending

2025-522376-82-00 allergic diseases (allergic rhinosinusitis, allergic as 5
A PROJECT FOR TWO MULTICENTRE, PROSPECTIVE OPEN LABEL RANDOMIZED CLINICAL STUDIES TO EVALUATE THE EFFECT OF TARGETED THERAPY BASED ON KIDNEY… Pending

2024-517861-18-00 Idiopathic IgA nephropathy (IgAN) 5
Randomised efficacy and safety clinical trial of PQ Birch in subjects with seasonal allergic rhinitis and/or rhinoconjunctivitis induced by … Pending

2023-507427-28-00 seasonal allergic rhinitis and/or rhinoconjunctivitis 5
A clinical trial to evaluate the efficacy and safety of a mixture of allergenic extracts of D. pteronyssinus and D. farinae, in patients suf… Pending

2025-521230-29-00 Allergic rhinoconjunctivitis to Dermatophagoides pteron 5
A First-in-Human, Open-label, Phase 1 Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy o… Pending

2025-525113-22-00 Rheumatoid Arthritis 1
A Double-Blind, Randomized, Placebo-Controlled Study to Investigate the Safety and Efficacy of Aritinercept, a Dual BAFF/APRIL Inhibitor, in… Pending

2025-525127-27-00 Generalized Myasthenia Gravis 9
IDENTIFICATION OF SYNOVIAL BIOMARKERS OF RESPONSE TO IXEKIZUMAB IN REFRACTORY PSORIATIC ARTHRITIS: THE PRECISE STUDY. Pending

2025-521259-21-00 PSORIATIC ARTHRITIS 6