Immune System Diseases

905 trials 381 recruiting

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A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Phase 2a Study With an Open-Label Extension Evaluating the Efficacy and Safety … Recruiting

2024-520098-12-00 Cutaneous Lupus Erythematosus 4 2026-02-16
A Multi-Stage Study to Test a New Drug in Healthy Adult Volunteers, Then in Adults with Ulcerative Colitis Recruiting

2025-522702-21-00 Ulcerative Colitis is a type of inflammatory bowel dise 4 2026-01-26
A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults (BARICADE-DELAY) Recruiting

2025-521797-34-00 Diabetes Mellitus, Type 1 5 2026-01-20
STOP-HAE: A Phase 3 Study of ADX-324 in HAE Recruiting

2025-521352-38-00 Hereditary Angioedema 5 2026-01-16
A study to learn how safe bimekizumab is and how well it works in adults with palmoplantar pustulosis Recruiting

2024-520337-80-00 Palmoplantar Pustulosis 5 2026-01-07
A randomized controlled phase II, double blinded trial to investigate pulmonary function after treatment with rituximab compared to placebo … Recruiting

2024-517667-23-00 Granulomatous Lymphocytic Interstitial Lung Disease (GL 4 2025-12-17
A study to test how well an oral medication called rilzabrutinib works and how safe it is for adults with immune thrombocytopenia (ITP) who … Recruiting

2025-522070-36-00 immune thrombocytopenia (ITP) 5 2025-12-15
A Study to Assess the Efficacy and Safety of RO7790121 in Patients with Moderate to Severe Rheumatoid Arthritis who have not Responded to or… Recruiting

2025-521034-28-00 Moderate to Severe Rheumatoid Arthritis (RA) 4 2025-12-05
IL-6 aGVHD Siltuximab: A phase II study to assess the efficacy and tolerability of siltuximab plus corticosteroids in first line treatment o… Recruiting

2024-510924-38-00 Grade III/IV acute graft versus host disease of the liv 4 2025-11-19
Phase III clinical trial to evaluate the efficacy and safety of specific immunotherapy with mannanconjugated allergoids for the treatment of… Recruiting

2023-508547-51-00 Aetiological treatment of moderate-to-severe allergic r 5 2025-11-18
PET-Based Imaging of Radiolabeled CIT-013 Recruiting

2025-522189-60-00 Inflammatory mediated immune diseases 4 2025-11-04
A Phase III, Open-label, Single Arm, Prospective, Multicenter Study to Assess Efficacy and Safety of Kedrion Intravenous Human Normal Immuno… Recruiting

2023-507115-35-00 Chronic Immune Thrombocytopenia (ITP) 5 2025-11-03
Study to assess the pharmacokinetics, safety, and tolerability of iptacopan in pediatric PNH patients Recruiting

2024-515926-10-00 Paroxysmal Nocturnal Hemoglobinuria (PNH) 5 2025-10-28
The efficacy and safety of Intramuscular Methylprednisolone in patients with Hand OsteoArthritis: the IMHOA trial Recruiting

2024-518344-20-00 Hand osteoarthritis 5 2025-10-28
A study to understand the safety and benefit of AlloNK® with rituximab in patients with hard-to-treat rheumatic diseases Recruiting

2025-520461-41-00 Systemic Sclerosis (SSc) 4 2025-10-22
A Study to Evaluate Different Targeted Therapies for Patients With Rheumatoid Arthritis Recruiting

2025-520721-21-00 Rheumatoid Arthritis 4 2025-10-20
A study to assess the effect and safety of efgartigimod IV in participants from 12 years to less than 18 years of age with chronic Immune Th… Recruiting

2025-521055-23-00 Chronic Idiopathic thrombocytopenic purpura 10 2025-10-07
A phase Ib, open-label, ascending dose study to assess safety, tolerability and pharmacokinetics of PIT565 in participants with rheumatoid a… Recruiting

2024-520196-27-00 Rheumatoid Arthritis 3 2025-10-01
Open-label Study of ELA026 in Participants with sHLH (short title) Recruiting

2025-520624-25-00 Secondary Hemophagocytic Lymphohistiocytosis (sHLH) 10 2025-09-19
Impact of dapagliflozin for the regulation of immunological activity in Membranous Nephropathy Recruiting

2023-507658-34-00 Membranous Nephropathy 10 2025-09-19
A Phase 1b, Open-Label Study of CLN-978 for the Treatment of Active, Moderate to Severe Sjogren’s Disease Recruiting

2025-521462-96-00 Sjogren's Disease 3 2025-08-05
A Study to Investigate the Safety and Efficacy of Pirtobrutinib in Adults with Immune Thrombocytopenia Recruiting

2024-518502-40-00 Immune Thrombocytopenia 9 2025-07-28
Multicenter clinical trial to evaluate efficacy and safety of sublingual immunotherapy in patients allergic to house mites, with rhinitis/rh… Recruiting

2023-505918-14-00 Aetiological treatment of moderate to severe rhinitis/r 5 2025-07-16
A Phase 3, Randomized, Open-Label Study of Axatilimab Versus Best Available Therapy in Participants With Chronic Graft-Versus-Host Disease A… Recruiting

2024-518973-32-00 Chronic Graft-Versus-Host Disease 5 2025-07-03