Immune system processes

92 trials 29 recruiting

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A Phase I First-in-Human Dose Escalation Trial to Evaluate the Safety and Efficacy of ARI-HER2 (HER2BBz CAR-T Cells) in Patients with HER2Po… Not authorised

2025-521052-35-00 Patients with HER2Positive Advanced Breast Cancer 7
Phase 2 Open Label Prospective Dose-Ranging Clinical Trial with Escalation and Expansion Cohorts to Evaluate Safety, Tolerability, Pharmacok… Not authorised

2024-510582-42-00 Acute graft versus host disease (aGvHD) 4
LONGITUDINAL FOLLOW-UP OF SARS-COV-2 IMMUNITY IN IMMUNOCOMPROMISED POPULATIONS IN BELGIUM (COVICO) A non-commercial multicenter academic pro… Pending

2024-518098-33-01 Healthy persons and immunocompromised patients (nursing 6
MULTICENTER, RANDOMIZED STUDY TO EVALUATE THE EFFICACY OF INDIVIDUALIZATION OF IMMUNOLOGICAL RISK BASED ON SELECTIVE BIOMARKERS (HLA EPLE… Pending

2025-520884-42-00 Kidney Transplant 6
Safety and efficacy of steering of immunosuppression based on BKPyV-specific T cells in case of BK Polyomavirus (BKPyV) DNAemia after kidney… Pending

2024-517219-56-00 BK Polyomavirus DNAemia after kidney transplantation 6
The optimal timing of vaccination in pregnancy: a multi-dimensional mechanistic approach to measure immune responses in pregnant women (MATI… Pending

2024-518692-56-00 Pregnant 6
TARGET-EBV in MS: Targeting Epstein Barr Virus with Tenofovir Alafenamide Fumarate in multiple sclerosis Pending

2025-522140-40-00 multiple sclerosis 4
TACmono LT Pending

2024-513394-42-01 Vaccination response 11
EarLy extra Measles immunisation during a measles Outbreak (ELMO) Pending

2024-513395-18-00 Healthy infants receiving a profylactic vaccine to prev 6
Phase IV study to evaluate the safety and efficacy of maribavir in reducing Epstein–Barr virus in young adult kidney transplant recipients. Pending

2025-524786-25-00 Transplant patients with high recurrent Epstein-Barr in 6
RESCAP to prevent peri- and post-surgical complications in open-heart surgery. Pending

2025-520551-84-00 systemic inflammation as side-effect of heart-lung mach 5
A Study to Assess Adverse Events, How the Drug Moves Through the Body and Effectiveness of Intravenous Infusions of ABBV-319 in Adult Partic… Recruiting

2024-519157-10-00 Systemic Lupus Erythematosus 3 2025-11-24
A study to find how well Dazodalibep works and how safe it is in participants with Sjôgren`s Syndrome Recruiting

2023-503904-10-00 Sjögren’s Syndrome With Moderate-to-severe Systemic Dis 5 2024-06-07
Crohn's Disease: Pharmacokinetics, Efficacy, and Safety of Risankizumab in Pediatric Subjects with Moderately to Severely Active Crohn's Dis… Recruiting

2022-502050-14-00 Crohn's disease 5 2024-06-04
This is a first in human study, in patients with severe bleeding disorder (hemophilia A), who has developed inhibitory antibodies against co… Recruiting

2022-502030-12-01 Treatment of patients with Hemophilia A who have develo 1 2022-10-13
An extension phase 2/3 study to test the safety of long term administration of oral PHA-022121 for acute treatment of angioedema attacks in … Recruiting

2023-505766-28-00 Hereditary angioedema 10 2022-10-10
Pharmacokinetics, safety, and efficacy of fisetin - A phase I and pilot phase IIa study Recruiting

2023-506284-34-00 Healthy 9 2026-03-24
Pneumoccocal vaccine response in patients without a spleen, vaccinated before or after spleen removal. Recruiting

2024-515363-63-00 Asplenia 6 2025-11-07
An open non-randomized phase IV trial examining interfering cross-reactivity in serological diagnostics of flavivirus infections in Swedish … Recruiting

2025-520655-92-00 No medical condition, prophylactic vaccine against deng 6 2025-09-11
Temporal characterization of Extracellular Vesicles during cellular therapy using CAR-T cells and during the occurrence of Immune effector C… Recruiting

2024-515328-35-00 hematology 6 2025-07-02
A study to find how well Dazodalibep works and how safe it is in participants with Sjôgren`s Syndrome Recruiting

2024-517513-32-00 Sjögren’s Syndrome 5 2025-05-16
Ravulizumab dose optimization Recruiting

2024-519207-10-00 Paroxysmal nocturnal hemoglobinuria (PNH) 6 2025-05-12
The impact of vaccine platform, age and HIV infection on germinal centre formation. Recruiting

2023-510354-16-00 HIV infection 11 2025-03-06
Combination of baricitinib and anti-TNF in rheumatoid arthritis Recruiting

2024-511442-39-00 Rheumatoid arthritis (RA) 5 2025-02-05