Immune system processes

92 trials 29 recruiting

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Open-Label Extension (OLE) Study to Evaluate the Safety of Efgartigimod in Adult Patients With Primary Sjögren’s Syndrome (pSS) Ended

2023-503915-14-00 Primary Sjögren's Syndrome 4 2023-11-15
A Study of LY3454738 in the Treatment of Adult Participants With Moderate-to-Severe Atopic Dermatitis Ended

2022-502888-38-00 Atopic dermatitis 4 2023-09-25
Intradermal administration of a COVID-19 mRNA vaccine in elderly Ended

2023-503800-99-00 Adult volunteers (M/F) aged ≥75 years who are healthy o 4 2023-09-04
A study evaluating the effects of GLPG3667 given as oral treatment for up to 24 weeks in adults with dermatomyositis Ended

2022-501097-19-00 dermatomyositis 4 2023-08-09
A study to test the safety of MK-1654 and how well MK-1654 works in healthy infants Ended

2022-500350-42-01 Prevention of RSV 10 2022-11-07
A Phase 3 Study of Itolizumab in Combination with Corticosteroids for the Initial Treatment of Acute Graft Versus Host Disease (Complication… Ended

2024-516064-28-00 Acute Graft Versus Host Disease 5 2022-09-27
Efficacy and Safety of secukinumab in patients with new onset of giant cell arteritis who are in clinical remission Ended

2024-512856-40-00 Giant Cell Arteritis 5 2022-09-21
A blinded, placebo-controlled and randomized phase 2 study to test different doses of oral PHA-022121 for prophylaxis of angioedema attacks … Ended

2023-505549-18-00 Hereditary angioedema due to C1-Inhibitor Deficiency (T 4 2022-04-29
Study in highly sensitised kidney transplant patients with a high degree of antibodies against the donor's kidney to see the efficacy and sa… Ended

2024-511810-18-00 End stage chronic kidney disease (CKD) patients who are 5 2022-04-19
Prospective, open-label, single-arm, multicentre Phase 3 study to evaluate the pharmacokinetics, efficacy, tolerability, and safety of subcu… Ended

2024-511231-94-00 Human Normal Immunoglobulin 5 2021-10-27
Adjuvant dendritic cell immunotherapy complementing conventional therapy for pediatric patients with high-grade glioma and diffuse intrinsic… Ended

2024-515295-12-00 High-grade glioma (HGG) 4 2021-10-06
A 12-Month Clinical Research Study to evaluate a new investigational medication (siplizumab) compared to another medication (anti thymocyte … Ended

2023-507895-36-00 Renal Transplantation 4 2021-06-06
Cognitive function after liver transplantation comparing Tacrolimus formulations Ended

2024-513963-22-00 ICD 10: Z94.4 Liver transplant status 6 2020-12-09
A study of belimumab in children with systemic lupus erythematosus (SLE) Ended

2023-509413-37-00 Systemic Lupus Erythematosus 4 2020-01-17
OPTIMIZE Ended

2024-516509-22-00 kidney transplant 6 2019-07-22
The safety and efficacy of Alpha-1 Antitrypsin (AAT) for the prevention of graft‑versus-host disease (GVHD) in patients receiving hematopoie… Ended

2024-511164-92-00 Acute Graft versus host disease 10 2019-05-17
First-line immunotherapy using Wilms’ tumor protein 1 (WT1)-targeted dendritic cell vaccinations for malignant pleural mesothelioma Ended

2024-517970-35-00 Malignant Pleural Mesothelioma 4 2017-10-03
ARIISE - ASCs in recently diagnosed non-ischemic heart failure Ended

2025-520837-22-00 Non-ischemic heart failure with reduced ejection fracti 4
PRODIGE 76-IMMUNOBILADJ: Capecitabine plus durvalumab or capecitabine alone as adjuvant therapy in patients with resected biliary tract carc… Ended

2023-503807-27-00 Biliary tract carcinoma 4
Evaluation and promotion of specific adaptative immunity against polyomavirus (BKV) to prevent viral infection after kidney transplantation … Expired

2023-504309-35-00 Prevention viral infection (BKV) poliamavirus after kid 6