Mental Disorders

274 trials 116 recruiting

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A double blinded, balanced, randomized, two-treatment, two-period, two-sequence, single dose, crossover, bioequivalence study comparing Bupr… Ended

2024-516034-35-00 major depressive illness 2 2025-12-05
Randomised, crossover bioequivalence clinical trial of memantine 20 mg capsules versus memantine 20 mg film-coated tablets, after a single o… Ended

2025-523808-75-00 Alzheimer’s disease 2 2025-10-24
A randomised, double-blind, placebo-controlled phase Ib trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of … Ended

2025-522287-32-00 Depression 3 2025-10-22
The pivotal bioequivalence study comparing the test product to the reference product, which belongs to the group of medicines used in treatm… Ended

2025-523325-18-00 Bioequivalence study under fasting conditions 2 2025-10-15
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Lisdexa… Ended

2024-513517-12-00 ADHD 2 2025-10-01
Randomised, crossover bioequivalence clinical trial of escitalopram 10 mg capsules versus escitalopram 10 mg film-coated tablets, after a si… Ended

2025-522124-26-00 Antidepressants 2 2025-08-18
Phase I, first-in-man, randomised, placebo-controlled, single dose escalation study to investigate the effects of LPH-5 on safety, tolerabil… Ended

2024-512330-15-00 Depression 1 2025-08-05
A Phase 1 Randomized, Placebo-Controlled, Double-Blind Study of the Safety, Tolerability and Pharmacological Effects of PT00114 in Healthy V… Ended

2024-519316-13-00 Phase I study in healthy male and female volunteers. In 1 2025-08-01
A Phase 1, Randomized, Double-Blind, Placebo-Controlled, Adaptive Single Ascending Dose Study to Evaluate the Safety, Tolerability, and Phar… Ended

2025-521914-25-00 Schizophrenia 3 2025-07-31
A study to examine the effects of oral NTX-1955 on the brain in healthy adults. Ended

2025-521829-32-00 Generalized Anxiety Disorder (GAD) 3 2025-06-24
PainCart Study Evaluating the Analgesic Profile of SAGE-319 Ended

2025-521380-12-00 Disorders characterized by a deficit in GABAergic signa 3 2025-06-02
Study of Sunobinop on Alcohol Consumption in Alcohol Use Disorder Ended

2024-517105-85-00 Alcohol use disorder (AUD). 4 2025-05-26
The pivotal bioequivalence study comparing the test product to the reference product, which belongs to the group of medicines used in treatm… Ended

2025-521400-21-00 Not applicable (submitted trial is a BE study in health 2 2025-05-15
Study of safety, tolerability, pharmacokinetics and pharmacodynamics of MSD-001 in healthy participants Ended

2024-512939-67-00 Mental health disorders 1 2025-05-10
Randomised, crossover bioequivalence clinical trial of escitalopram 20 mg capsules versus escitalopram 20 mg film-coated tablets, after a si… Ended

2025-521069-28-00 Antidepressants 2 2025-03-21
Pilot study on the safety and feasibility of intravenous opioid agonist therapy (OAT) with Hydagelan® (hydromorphone hydrochloride) in Vien… Ended

2024-519652-90-01 Opioid dependence: Opioid dependence is a serious and u 4 2025-02-17
Randomised, crossover bioequivalence clinical trial of vortioxetine 20 mg film-coated tablets, after a single oral dose administration to he… Ended

2024-516497-29-00 Antidepressant 2 2025-02-11
N-acetylcysteine for the treatment of cannabis dependence: working mechanisms Ended

2024-519855-27-00 Cannabis dependence 6 2025-01-15
An open label, balanced, randomized, two-treatment, two-period, two-sequence, single-dose, crossover, bioequivalence study comparing Dextroa… Ended

2023-509874-48-00 ADHD 2 2025-01-09
Cannabidiol for reducing drinking in alcohol use disorder and modifying the effects of alcohol on the brain and the liver Ended

2024-517751-13-01 Psychiatric disorders 4 2024-12-26
A study to assess the efficacy and safety of lumateperone in patients with Bipolar Mania Ended

2024-513036-26-00 Bipolar I Disorder (Bipolar Mania) 5 2024-12-20
A study to assess the efficacy and safety of lumateperone in patients with Bipolar Mania Ended

2024-513037-20-00 Bipolar I Disorder (Bipolar Mania) 5 2024-12-19
Efficacy and Safety of REL-1017 for Major Depressive Disorder Ended

2023-507399-27-00 Major Depression 5 2024-12-04
A Randomized, Double-blind, Multicenter, Placebo-controlled Study of Adjunctive Aticaprant Plus an Antidepressant for Relapse Prevention in … Ended

2024-511057-22-00 Major Depressive Disorder (MDD) with Moderate-to-severe 5 2024-12-04