Neoplasms

3,817 trials 1,526 recruiting

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A Randomized, Double-Blind, Placebo-Controlled, MultiRegional Phase III Clinical Study of Toripalimab Alone or in Combination With Tifcemal… Recruiting

2023-507097-41-01 Patients with limited-stage small cell lung cancer (LS- 5 2025-03-20
A prospective randomized open-label phase II clinical study evaluating the efficacy and safety of zoledronic acid addition to standard thera… Recruiting

2024-519446-67-00 Glioblastoma 4 2025-03-06
Bemarituzumab in patients with FGFR2b-positive advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction, who failed… Recruiting

2024-512484-31-00 FGFR2b-positive, advanced or metastatic adenocarcinoma 4 2025-02-28
IMPACT-AML: A RANDOMIZED PRAGMATIC CLINICAL TRIAL FOR RELAPSE OR REFRACTORY ACUTE MYELOID LEUKEMIA Recruiting

2024-514517-35-00 Acute myeloid leukemia 5 2025-02-27
Preservation of Fertility by Ovarian Stimulation Associated With Tamoxifen, Prior Chemotherapy for Breast Cancer (PRESAGE) Recruiting

2024-516282-37-00 Breast cancer 4 2025-02-18
Dose dense re-challenge of high dose methotrexate (hd-mtx) with glucarpidase (cpg2) for relapsed primary cns lymphoma (pcnsl): A phase 1 tri… Recruiting

2024-511900-17-00 Oncology: RELAPSED PRIMARY CNS LYMPHOMA 3 2025-02-14
A multicenter, Phase II, open label, randomized trial evaluating the efficacy of Tedopi plus docetaxel or Tedopi plus nivolumab as second-li… Recruiting

2024-518224-74-01 metastatic non-small-cell lung cancer 4 2025-02-07
KISIMA-02 vaccine-based immunotherapy for patients with pancreatic cancer Recruiting

2022-501854-12-01 G12D/G12V Pancreatic Ductal Adenocarcinoma 1 2025-02-05
Randomized Phase 3 Trial of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Ade… Recruiting

2024-513317-12-00 Pancreatic cancer 5 2025-02-05
A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants with Advanced Hematologic Maligna… Recruiting

2024-511457-22-00 Advanced Hematologic Malignancies 3 2025-01-30
A study to compare effects and safety of CT-P51 and Keytruda in patients with previously untreated metastatic lung cancer Recruiting

2024-514048-98-00 Previously Untreated Metastatic Non-Squamous Non-Small 5 2025-01-30
HEPATIC ARTERIAL INFUSION OF GEMCITABINE-OXALIPLATIN FOR SECOND-LINE THERAPY IN NON-METASTATIC UNRESECTABLE INTRA-HEPATIC CHOLANGIOCARCINOMA… Recruiting

2024-519132-17-00 NON-METASTATIC UNRESECTABLE INTRA-HEPATIC CHOLANGIOCARC 4 2025-01-29
A randomized study in testicular cancer without metastasis, comparing two different types of chemotherapy used to reduce the risk of relapse Recruiting

2024-518399-29-00 Testicular cancer 5 2024-12-27
A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham… Recruiting

2023-504655-27-00 Primary Indeterminate Lesions or Small Choroidal Melano 5 2024-12-23
A study comparing niraparib with temozolomide in adult participants with newly-diagnosed, MGMT unmethylated glioblastoma Recruiting

2024-513077-48-00 O6-methylguanine methyltransferase (MGMT) unmethylated 5 2024-12-19
A randomized phase 3, double-blind, placebo-controlled study of elacestrant plus everolimus versus elacestrant in patients with estrogen rec… Recruiting

2024-512926-27-00 patients with estrogen receptor-positive/human epiderma 5 2024-12-12
COLLISION RELAPSE trial Recurrent colorectal liver metastases: repeat local treatment +/- neoadjuvant systemic therapy, a phase III prospect… Recruiting

2024-515341-41-01 Colorectal liver metastases 11 2024-12-11
Letrozole for Estrogen/Progesterone Receptor positive low-grade serous Epithelial ovarian cancer. A randomized phase III trial. LEPRE Trial Recruiting

2024-516874-31-00 Patients with a low-grade serous epithelial carcinoma o 5 2024-12-10
Volrustomig Priming Regimens Exploratory Phase II Platform Study Recruiting

2023-509482-20-00 Solid Tumors 4 2024-12-03
NEOADJUVANT ATEZOLIZUMAB AND ADJUVANT ATEZOLIZUMAB + BEVACIZUMAB IN COMBINATION WITH PERCUTANEOUS RADIOFREQUENCY ABLATION OF SMALL HCC: A MU… Recruiting

2024-519113-59-00 Hepatocellular carcinoma 4 2024-11-20
A study to investigate efficacy and safety of INT230-6 compared with US standard of care in participants aged ≥ 18 years old with metastatic… Recruiting

2024-512423-36-00 Undifferentiated pleomorphic sarcoma 5 2024-11-20
A study to test the safety and efficacy of a new drug, AZD3470, in patients with advanced solid tumours. Recruiting

2023-506757-38-00 Advanced/metastatic solid tumors that are MTAP deficien 1 2024-11-14
AFAN trial. Phase Ib/II study to investigate the safety and efficacy of Afatinib when administered as therapy in Fanconi anemia patients wit… Recruiting

2024-511477-29-00 Patients diagnosed with unresectable and / or metastati 4 2024-11-08
Study Evaluating Tarlatamab After Chemoradiotherapy in Limited‑Stage Small‑Cell Lung Cancer (DeLLphi-306) Recruiting

2023-506235-15-00 Limited-Stage Small-Cell Lung Cancer (LS SCLC) 5 2024-11-07