Nervous System Diseases

1,005 trials 421 recruiting

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A PHASE I, COMBINED STUDY OF THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF SZV-1287 IN HEALTHY MALE VOLUNTEERS AFTER SINGLE ASCENDING AN… Recruiting

2024-519485-50-00 neuropathic pain 1 2024-11-25
A Phase 2 Study of Obexelimab in Patients with Relapsing Multiple Sclerosis Recruiting

2024-512707-40-00 RELAPSING MULTIPLE SCLEROSIS 4 2024-11-07
Efficacy and safety study of frexalimab (SAR441344) in adults with relapsing forms of multiple sclerosis Recruiting

2023-504358-36-00 multiple sclerosis 5 2024-10-17
CIAO@TBI Recruiting

2024-514488-24-02 Traumatic Brain Injury 4 2024-10-09
LONG-TERM EFFECTIVENESS AND SAFETY EVALUATION OF OCRELIZUMAB IN FRENCH PATIENTS WITH PROGRESSIVE MS: CONSONANCE EXTENSION STUDY Recruiting

2024-516433-13-00 Progressive multiple sclerosis 5 2024-09-19
A Phase 2 Double-Blind, Randomized, Placebo-Controlled Trial to Evaluate the Efficacy and Safety of Intravenous Sabirnetug in Early Alzheime… Recruiting

2023-509807-34-00 Early Alzheimer’s Disease (Mild Cognitive Impairment an 4 2024-08-12
(PREVENT)A Randomized, Double-blind, Placebo-controlled Trial on the Prevention of Chronic Postoperative Pain after Inguinal Hernia and Knee… Recruiting

2024-511010-21-00 chronic postoperative pain 6 2024-07-22
Safety and Efficacy of 3 Dose Levels of NMD670 in Adult Patients with Myasthenia Gravis Recruiting

2023-507539-40-00 Myasthenia Gravis 4 2024-07-19
A study to learn how safe fenfluramine is, how well it works, and how it moves through the bloodstream in infants with Dravet syndrome Recruiting

2022-502359-75-00 Dravet syndrome 5 2024-07-03
Long Term Study of Ecopipam Tablets in Children, Adolescents and Adults with Tourette’s Disorder Recruiting

2023-503545-67-00 Tourette's Disorder 5 2024-04-30
An Open label, Safety Clinical trial of (+)-α-dihydrotetrabenazine in patients with moderate to severe tardive dyskinesia Recruiting

2023-509518-12-01 Tardive dyskinesia 4 2024-04-16
Long-term Extension Study to Assess Adverse Events and Tolerability of Oral Atogepant Tablets in Pediatric Participants (6 to 17 Years of Ag… Recruiting

2022-501099-24-00 Migraine 5 2023-12-22
Randomised, double-blind, placebo-controlled study to assess safety and efficacy of PRI-002 in patients with MCI or mild dementia due to Alz… Recruiting

2022-503148-41-00 Alzheimer's disease 4 2023-12-01
Clinical trial of (+)-α-dihydrotetrabenazine in patients with moderate to severe tardive dyskinesia with open-label Part I and randomized, d… Recruiting

2024-516852-17-00 Tardive dyskinesia 4 2023-11-13
A Study to Assess the Adverse Events and Change in Disease Activity of Oral Atogepant Tablets in Pediatric Participants (6-17 Years of Age) … Recruiting

2022-501100-94-00 Episodic Migraine 5 2023-11-08
A Phase 3, Open-label, Single-arm, Multicenter Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Efficacy, Safety, and Immunogenicit… Recruiting

2022-501882-29-00 Generalized Myasthenia Gravis (gMG) 5 2023-11-03
A randomized study of XEN1101 versus placebo in Primary Generalised Tonic Clonic Seizures (X-ACKT) Recruiting

2022-502286-16-00 Primary Generalized Tonic-Clonic Seizures 5 2023-10-27
A Multinational, Multicenter Study With an Open-Label Phase 1b and a Randomized, Double-Blind, Placebo-Controlled Phase 3 Followed by an Ope… Recruiting

2023-509672-42-00 GRIN-related neurodevelopmental disorder 5 2023-02-02
A Study to Evaluate Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Satralizumab in Patients with NMDAR or LGI1 mediated autoimm… Recruiting

2023-504226-18-00 NMDAR or LGI1 mediated autoimmune Encephalitis 5 2022-11-30
A Study to Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, and Pharmacodynamics of Satralizumab in Pediatric Patients with Aquapo… Recruiting

2023-507817-85-00 Neuromyelitis Optica Spectrum Disorder (NMOSD) 5 2022-04-21
Remyelination in Multiple Sclerosis: a PET-MR longitudinal study investigating individual profiles of myelin repair and the contribution of … Recruiting

2024-512761-13-00 Remyelination in Multiple Sclerosis 5 2022-01-24
Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate Efficacy, Safety, and Tolerability of IMU-838 in Patients with P… Recruiting

2024-514617-35-00 Progressive forms of Multiple Sclerosis 4 2021-12-20
Open label extension study for monitoring long-term safety in patients with Myoclonic Astatic Epilepsy (Doose-Syndrome) receiving Fenflurami… Recruiting

2024-518520-77-00 Myclonic-astatic epilepsy 4 2021-11-24
Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis Recruiting

2024-511686-11-00 Multiple Sclerosis in pediatric patients 5 2021-10-05