Pathological Conditions, Signs and Symptoms

144 trials 75 recruiting

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A Study of Nicotine Freshmint Mouthspray in E-cigarette Users Willing to Quit Ended

2023-505036-35-00 Vaping cessation in e-cigarette users 5 2024-04-23
Multi-center study of a fentanyl nasal spray compared with placebo nasal spray for postoperative pain management. Ended

2024-519625-38-00 Postoperative pain relief 5 2024-04-14
A study to assess the efficacy and safety of tigulixostat at different doses as compared to a control drug (allopurinol) in gout patients wi… Ended

2022-501421-20-00 Gout with hyperuricemia 5 2024-04-09
[HIBOU] : A phase I, single-center, randomized, double-blind, single-dose escalation, placebo-controlled clinical study to evaluate the safe… Ended

2023-509035-30-00 Antidote 1 2024-01-18
Study comparing radiotherapy combined with cetuximab + Xevinapant (study drug) with radiotherapy combined with cetuximab + placebo in patien… Ended

2022-502584-38-00 Locally advanced squamous cell carcinoma of the head an 5 2023-12-12
Improvement of Quality of Life by Cannabinoids in Oncologic Patients (BELCANTO) Ended

2024-518917-24-00 oncology, palliative care, quality of life 4 2023-11-08
Efficacy and Tolerability of AP707 in Patients with Chronic Back Pain Ended

2022-502151-54-00 Chronic back pain 5 2023-11-02
Efficacy and Tolerability of AP707 in Patients with chronic Pain due to Diabetic Polyneuropathy Ended

2022-500897-32-00 Chronic pain due to diabetic polyneuropathy 5 2023-11-02
Efficacy and Tolerability of AP707 in Patients with chronic Pain due to traumatic or post-operative peripheral Neuropathy Ended

2022-500898-13-00 Chronic Pain due to traumatic or post-operative periphe 5 2023-11-02
Efficacy and Tolerability of AP707 in Patients with chronic pain due to central Neuropathy of any Genesis Ended

2022-500899-66-00 Chronic pain due to central Neuropathy of any Genesis 5 2023-11-02
Milademetan and fulvestrant in GATA3-mutant, ER-positive, HER2-negative advanced or metastatic breast cancer patients (DEMETER) Ended

2022-502360-21-00 GATA3-mutant, ER-positive, HER2-negative advanced or me 4 2023-10-12
A two-part, open-label study to assess the pharmacokinetics, pharmacodynamics and safety of single doses of inhaled and intravenously admini… Ended

2022-503037-63-00 Phase I, Clinical trial in healthy males and females in 3 2023-08-17
ARTEMIS: A Phase 3 Study of Ravulizumab to Protect Patients with Chronic Kidney Disease (CKD) from Cardiac Surgery Associated Acute Kidney … Ended

2022-501802-36-00 Prevention of cardiac surgery associated acute kidney i 5 2023-06-16
A Phase IIa Study to assess Safety, Tolerability, and Pharmacodynamics of AZD4831 in Adult Participants with Non-cirrhotic NASH with Fibrosi… Ended

2022-500594-13-00 "Non-Alcoholic Steatohepatatis (NASH) is the progressiv 4 2022-12-14
Phase II Study of Fedratinib and Nivolumab Combination in Patients with Myelofibrosis and Resistance or Suboptimal Response to JAK-inhibitor… Ended

2024-513953-64-00 Primary and secondary Myelofibrosis 4 2022-06-23
Hemodynamic Phenotype-Based,Capillary Refill Time-Targeted Resuscitation In Early Septic Shock:ANDROMEDA-SHOCK-2 Ended

2024-519691-10-00 Septic Shock 6 2022-05-27
VIRTUOSE: Efficiency of sildenafil on the absolute claudication distance of peripheral arterial disease patients with intermittent claudicat… Ended

2024-516429-30-00 Peripheral arterial disease 5 2021-11-24
A phase I/II study to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and efficacy of FR104, a novel antagonist pegylate… Ended

2024-516577-76-00 Kidney transplant 8 2021-06-28
Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy Ended

2024-515892-36-00 C3 glomerulopathy 4 2020-01-01
Efficacy of Olaparib in advanced cancers occurring in patients with germline mutations or somatic tumor mutations in homologous recombinatio… Ended

2024-518522-32-00 Basket tumors 4 2019-02-07
Effectiveness and Safety of Sparsentan as treatment for Primary Focal Segmental Glomerulosclerosis (FSGS) Ended

2023-505494-32-00 Focal segmental glomerulosclerosis (FSGS) 5 2018-10-15
Effects of a single denosumab injection on reduction of total contact cast treatment and consolidation of bone fractures caused by acute Cha… Ended

2024-518637-28-00 Charcot, diabetes 5
Monalizumab and MEDI5752 in patients with MSI and/or dMMR metastatic cancer (MONAMI) Ended

2024-511857-23-00 cancerology 4
Prevention of thrombotic events in the context of long distance flights Ended

2024-515630-33-00 Symptomatic leg vein thrombosis 5