Respiratory Tract Diseases

568 trials 207 recruiting

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[68Ga]-FAPI PET/CT to visualize the activity of fibrogenic cells in patients with non-resolving shock lung. Recruiting

2024-517257-27-00 Non-resolving ARDS 11 2024-11-24
Randomised, double-blind, multicentre, phase III clinical trial to evaluate the efficacy and safety of dexamethasone compared to placebo in … Recruiting

2024-513209-30-00 Severe Influenza 5 2024-11-20
Effect of dual bronchodilation with umeclidinium/vilanterol on patients with COPD, hyperinflation and heart failure Recruiting

2024-519513-61-00 Chronic obstructive pulmonary diseases with Heart Failu 6 2024-11-20
An open-label study to assess reduction of daily asthma medication with tezepelumab in patients 12 to 80 years of age with severe asthma Recruiting

2024-512113-41-00 Severe Asthma 5 2024-11-20
The PREDMETH trial: Effectiveness of methotrexate versus prednisone as first-line therapy for pulmonary sarcoidosis – A randomized controlle… Recruiting

2024-514055-15-00 Pulmonary sarcoidosis 6 2024-11-19
QUIDOSE. Randomized controlled trial testing the efficacy of hydroxychloroquine combined with low dose corticosteroid therapy in pulmonary s… Recruiting

2024-516101-23-00 Sarcoidosis 5 2024-10-28
A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CO… Recruiting

2023-508760-29-00 Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) 5 2024-10-21
Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis Recruiting

2023-504755-26-00 Bronchiectasis 4 2024-10-21
PERi-operative Selective Decontamination of the Digestive tract to prevent severe infectious complications after Esophagectomy: a Randomized… Recruiting

2023-504144-33-01 esophageal cancer 11 2024-10-17
A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis Recruiting

2023-508817-18-00 Perennial Allergic Rhinitis (PAR) 5 2024-10-08
Comparison between ABP 234 and Keytruda® (Pembrolizumab) Recruiting

2024-514304-14-00 Advanced or Metastatic Non-squamous Non-Small Cell Lung 1 2024-10-08
The randomized, double blind study phase III.b of the Comprehensive assessment of the musculoskeletal health in children with cystic fibrosi… Recruiting

2024-517886-18-00 Cystic fibrosis and problems with bone metabolism, bone 5 2024-10-02
OPEN-LABEL PHASE II EFFICACY STUDY OF REPOTRECTINIB IN FRAIL (PS ≥2) AND /OR ELDERLYPATIENTS WITH ROS1-REARRANGED ADVANCED NSCLC Recruiting

2023-509073-23-00 Stage III/IV non-small-cell lung cancer (NSCLC) harbori 4 2024-10-01
Maintenance of durvalumab and olaparib after standard 1st line treatment (carboplatin/ cisplatin, etoposide, durvalumab) in HRD positive ext… Recruiting

2024-512373-27-00 Advanced/inoperable or metastatic small-cell lung cance 4 2024-09-30
A Placebo-Controlled Study of Inhaled Pirfenidone in Progressive Pulmonary Fibrosis Recruiting

2023-508429-29-00 Progressive Pulmonary Fibrosis 4 2024-09-26
tislelizUMaB in canceR patients with molEcuLar residuaL disease (UMBRELLA) Recruiting

2023-503316-33-00 patients with a positive status for molecular residual 5 2024-09-26
A phase-2b controlled study to evaluate the humoral and cellular immune response and safety following one and two doses of an adjuvanted RSV… Recruiting

2024-513187-25-00 Respiratory syncytial virus 4 2024-09-10
A follow-up study to test long-term treatment with BI 1015550 in people with pulmonary fibrosis who took part in a previous study with BI 10… Recruiting

2023-507353-15-00 idiopathic pulmonary fibrosis (IPF) 5 2024-09-10
Dose tapering and Early Discontinuation to InCreAse cosT-effictIveness Of immunotherapy for Non-small cell lung carcinoma trial number 1 (NV… Recruiting

2024-516195-15-00 Advanced NSCLC 5 2024-09-10
A first-in-human study to investigate the safety and tolerability of a new antibody-guided drug delivery treatment for patients with therapy… Recruiting

2024-511074-80-01 Platinum-resistant high-grade ovarian cancer (PROC) or 7 2024-09-06
A study to assess the efficacy and safety of OATD-01 for the treatment of active pulmonary sarcoidosis. Recruiting

2023-506642-23-01 Active Pulmonary Sarcoidosis 4 2024-08-28
A Phase 1/2, Multicenter Study Evaluating the Safety, Tolerability, and Biodistribution of RCT2100 with Single-Ascending Doses in Healthy Pa… Recruiting

2024-512169-15-00 Cystic Fibrosis 7 2024-08-28
Palliation of Dyspnea and Cough using Morphine in patients with Fibrotic Interstitial Lung Disease Recruiting

2023-503700-81-00 Fibrotic Interstitial Lung Disease 6 2024-08-23
A randomized trial of multi-factorial primary prevention in high risk subjects candidate to a lung cancer early detection CT program Recruiting

2024-513660-26-00 Subjects at high risk of inflammatory state and mortali 4 2024-08-06