A Randomized, Open-Label, Single-Dose, Parallel-Group Study to Evaluate the Relative Bioavailability of LY03010 versus Xeplion® after Intramuscular Injection in Healthy Subjects

2022-502179-48-00 Protocol LY03010/CT-EUR-101 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 23 Feb 2023 · End 12 Feb 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol LY03010/CT-EUR-101

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 170
Countries 1
Sites 1

Schizophrenia

Key facts

Sponsor
Geneora Pharma (Shijiazhuang) Co. Ltd., Geneora Pharma (Shijiazhuang) Co. Ltd.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Nervous System Diseases [C10]
Trial duration
23 Feb 2023 → 12 Feb 2024
Decision date (initial)
2023-02-20
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Schizophrenia

VersionLevelCodeTermSystem organ class
20.0 PT 10039626 Schizophrenia 100000004873

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Geneora Pharma (Shijiazhuang) Co. Ltd.

Sponsor organisation
Geneora Pharma (Shijiazhuang) Co. Ltd.
Address
Runjiang Headquarters International Building 5th Floor, No. 455 Yuhua East Rd, High-Tech Zone No. 455 Yuhua East Rd High-Tech Zone
City
Shijiazhuang
Postcode
050031
Country
China

Scientific contact point

Organisation
Geneora Pharma (Shijiazhuang) Co. Ltd.
Contact name
Maggie Wang

Public contact point

Organisation
Geneora Pharma (Shijiazhuang) Co. Ltd.
Contact name
Maggie Wang

Geneora Pharma (Shijiazhuang) Co. Ltd.

Sponsor organisation
Geneora Pharma (Shijiazhuang) Co. Ltd.
Address
Runjiang Headquarters International Building 5th Floor, No 455 Yuhua East Rd, High Tech Zone No 455 Yuhua East Rd High Tech Zone
City
Shijiazhuang
Postcode
050031
Country
China

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Portugal Ended 170 1
Rest of world 0

Investigational sites

Portugal

1 site · Ended
Blueclinical Investigacao E Desenvolvimento Em Saude Lda.
Medical Management, East Wing, Rua De Sarmento De Beires 153 3rd Floor 4 Floor, Porto

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Portugal 2023-02-23 2024-02-12 2023-02-23 2023-09-10

Application history

4 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2022-10-27 Portugal Acceptable
2023-01-25
2023-02-20
2 NON SUBSTANTIAL MODIFICATION NSM-1 2023-02-20 Portugal Acceptable
2023-01-25
2023-02-20
3 NON SUBSTANTIAL MODIFICATION NSM-2 2024-02-28 Portugal Acceptable
2023-01-25
2024-02-28
4 NON SUBSTANTIAL MODIFICATION NSM-3 2024-02-28 Portugal Acceptable
2023-01-25
2024-02-28