Effect of mesenchymal stem cells on healing of foot ulcers in diabetes patients. A phase I pilot study.

2023-505961-10-00 Protocol STEMFOOT Phase I and Phase II (Integrated) - Other Ended

Start 15 Dec 2022 · End 28 Nov 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol STEMFOOT

Overview

Sponsor-declared trial summary

Phase Phase I and Phase II (Integrated) - Other
Status Ended
Participants planned 30
Countries 1
Sites 1

Diabetic foot ulcus

Key facts

Sponsor
Cell2cure ApS
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Skin and Connective Tissue Diseases [C17]
Trial duration
15 Dec 2022 → 28 Nov 2025
Decision date (initial)
2023-07-10
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2023-505961-10-00
EudraCT number
2022-001589-37
ClinicalTrials.gov
NCT05595681

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Diabetic foot ulcus

VersionLevelCodeTermSystem organ class
21.1 LLT 10012664 Diabetic foot ulcer 10040785

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Cell2cure ApS

Sponsor organisation
Cell2cure ApS
Address
Kajeroedgaard 9
City
Birkeroed
Postcode
3460
Country
Denmark

Scientific contact point

Organisation
Cell2cure ApS
Contact name
CEO & Clinical Director

Public contact point

Organisation
Cell2cure ApS
Contact name
CEO & Clinical Director

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Denmark Ended 30 1
Rest of world 0

Investigational sites

Denmark

1 site · Ended
Bispebjerg Hospital
Copenhagen Diabetes Foot Center, Department of Endocrinology, University of Copenhagen, Bispebjerg Bakke 23, 2400, Copenhagen Nv

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Denmark 2022-12-15 2022-12-15 2025-11-28

Application history

8 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-05-30 Denmark Acceptable
2023-06-14
2023-07-10
2 SUBSTANTIAL MODIFICATION SM-1 2023-08-24 Denmark Acceptable
2023-09-18
2023-09-18
3 SUBSTANTIAL MODIFICATION SM-2 2023-12-15 Denmark Acceptable
2024-01-23
2024-02-09
4 SUBSTANTIAL MODIFICATION SM-3 2024-03-08 Denmark Acceptable
2024-04-02
2024-04-03
5 NON SUBSTANTIAL MODIFICATION NSM-1 2024-07-18 Denmark Acceptable
2024-04-02
2024-07-18
6 NON SUBSTANTIAL MODIFICATION NSM-2 2024-07-22 Denmark Acceptable
2024-04-02
2024-07-22
7 SUBSTANTIAL MODIFICATION SM-4 2024-07-22 Denmark Acceptable
2024-07-23
2024-07-23
8 SUBSTANTIAL MODIFICATION SM-6 2025-05-21 Denmark Acceptable with conditions
2025-06-06
2025-06-06