An Open Label, Two Periods, Two Sequences, Crossover, Randomized Multiple Dose Bioequivalence Study of Guanfacine 7 MG Prolonged-Release Tablets (Test Formulation) vs. Equal Dose of Intuniv® Prolonged-Release Tablets (Reference Formulation) in Healthy Male Volunteers Under Fasting Conditions

2023-506596-10-00 Protocol GFC-BEMD-01-NXP/23 Human pharmacology (Phase I) - Bioequivalence study Ended

Start 31 Jan 2024 · End 13 May 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol GFC-BEMD-01-NXP/23

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 42
Countries 1
Sites 1

Study performed on healthy volunteers.

Key facts

Sponsor
neuraxpharm Arzneimittel GmbH
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male
Therapeutic area
Psychiatry and Psychology [F] - Mental Disorders [F03]
Trial duration
31 Jan 2024 → 13 May 2024
Decision date (initial)
2024-01-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Study performed on healthy volunteers.

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

neuraxpharm Arzneimittel GmbH

Sponsor organisation
neuraxpharm Arzneimittel GmbH
Address
Elisabeth-Selbert-Strasse 23, Richrath Richrath
City
Langenfeld (rheinland)
Postcode
40764
Country
Germany

Scientific contact point

Organisation
neuraxpharm Arzneimittel GmbH
Contact name
neuraxpharm Arzneimittel GmbH

Public contact point

Organisation
neuraxpharm Arzneimittel GmbH
Contact name
Neuraxpharm Pharmaceuticals S.L. Clinical Research Department, Barcelona

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Romania Ended 42 1
Rest of world 0

Investigational sites

Romania

1 site · Ended
3s Pharmacological Consultation & Res. S.R.L.
Clinical Research Department, Comuna Bosanci, Calea Falticeni Nr 45, Cumparatura

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Romania 2024-01-31 2024-05-13 2024-01-31

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2023-08-09 Romania Not acceptable
2023-11-27
2023-12-04