A study to investigate the similarity of two different Tiotropium inhalers in healthy volunteers.

2023-509025-41-00 Protocol CIX23001 Human pharmacology (Phase I) - Bioequivalence study Ended

End 26 Nov 2025 · Status Ended · 1 EU/EEA countries · 2 sites · Protocol CIX23001

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 40
Countries 1
Sites 2

No therapeutic indication in the current trial with healthy volunteers.

Key facts

Sponsor
CCDRD Cooperative Clinical Drug Research and Development AG, Invox Belgium
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Respiratory Tract Diseases [C08]
Trial duration
completed 26 Nov 2025
Decision date (initial)
2024-10-07
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

No therapeutic indication in the current trial with healthy volunteers.

VersionLevelCodeTermSystem organ class
21.1 LLT 10010952 COPD 10038738

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

CCDRD Cooperative Clinical Drug Research and Development AG

Sponsor organisation
CCDRD Cooperative Clinical Drug Research and Development AG
Address
Lindenallee 70, Dahlwitz-Hoppegarten Dahlwitz-Hoppegarten
City
Hoppegarten
Postcode
15366
Country
Germany

Scientific contact point

Organisation
Invox Belgium
Contact name
Head of Regulatory

Public contact point

Organisation
Invox Belgium
Contact name
Head of Regulatory

Invox Belgium

Sponsor organisation
Invox Belgium
Address
Bioville Building Abis, Agoralaan Agoralaan
City
Diepenbeek
Postcode
3590
Country
Belgium

Scientific contact point

Organisation
Invox Belgium
Contact name
Head of Regulatory

Public contact point

Organisation
Invox Belgium
Contact name
Head of Regulatory

Locations

1 EU/EEA country · 2 investigational sites

By country

CountryMS statusPlanned subjectsSites
Bulgaria Ended 40 2
Rest of world 0

Investigational sites

Bulgaria

2 sites · Ended
Clinic of Clinical Pharmacology and Therapeutics UMHAT 'Tsaritsa Ioanna-ISUL' EAD
Clinic of Clinical Pharmacology and Therapeutics, 8 'Bialo more' Str., 1527, Sofia
Diagnostic Consultative Centre Ascendent EOOD
Bed space for short term stay, Ulitsa Bacho Kiro 47, 1202, Sofia

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-07-03 Bulgaria Acceptable
2024-09-02
2024-10-07
2 SUBSTANTIAL MODIFICATION SM-1 2024-11-06 Bulgaria Acceptable
2024-12-04
2024-12-05