A TQT Study to Investigate the Effect of Enpatoran on Cardiac Repolarization in Healthy Participants

2024-512841-17-00 Protocol MS200569_0065 Human pharmacology (Phase I) - Other Ended

Start 4 Sep 2024 · End 2 Dec 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol MS200569_0065

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 40
Countries 1
Sites 1

Healthy

Key facts

Sponsor
Merck Healthcare KGaA
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Immune System Diseases [C20]
Trial duration
4 Sep 2024 → 2 Dec 2024
Decision date (initial)
2024-07-17
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Healthy

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Merck Healthcare KGaA

Sponsor organisation
Merck Healthcare KGaA
Address
Frankfurter Strasse 250
City
Darmstadt
Postcode
64293
Country
Germany

Scientific contact point

Organisation
Merck Healthcare KGaA
Contact name
Global Regulatory Affairs

Public contact point

Organisation
Merck Healthcare KGaA
Contact name
Global Regulatory Affairs

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Germany Ended 40 1
Rest of world 0

Investigational sites

Germany

1 site · Ended
Nuvisan GmbH
Clinical Services, Wegenerstrasse 13, Ludwigsfeld, Neu-Ulm

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Germany 2024-09-04 2024-12-02 2024-09-10 2024-09-19

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-05-22 Germany Acceptable
2024-07-15
2024-07-17
2 SUBSTANTIAL MODIFICATION SM-1 2024-09-24 Germany Acceptable
2024-10-15
2024-10-16