Bioequivalence of Metamizole Sodium 500 mg Film-Coated Tablets in Healthy Participants Under Fasting Conditions.

2024-514447-29-00 Protocol b4-23-TEMt Human pharmacology (Phase I) - Bioequivalence study Ended

Start 2 Dec 2024 · End 26 Dec 2024 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol b4-23-TEMt

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Ended
Participants planned 30
Countries 1
Sites 1

No medical condition.

Key facts

Sponsor
Alkaloid AD Skopje
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Not possible to specify
Trial duration
2 Dec 2024 → 26 Dec 2024
Decision date (initial)
2024-11-26
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

No medical condition.

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Alkaloid AD Skopje

Sponsor organisation
Alkaloid AD Skopje
Address
Boulevard Aleksandar Makedonski 12
City
Skopje
Postcode
1000
Country
North Macedonia

Scientific contact point

Organisation
Alkaloid AD Skopje
Contact name
Luís Almeida

Public contact point

Organisation
Alkaloid AD Skopje
Contact name
Luís Almeida

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Portugal Ended 30 1
Rest of world 0

Investigational sites

Portugal

1 site · Ended
Blueclinical Investigacao E Desenvolvimento Em Saude Lda.
Medical Management, Rua De Sarmento De Beires 153 0 Floor 3rd Floor, 4250-449, Porto

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Portugal 2024-12-02 2024-12-26 2024-12-02 2024-12-09

Application history

3 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-09-20 Portugal Acceptable
2024-10-29
2024-11-26
2 SUBSTANTIAL MODIFICATION SM-1 2024-11-28 Portugal Acceptable 2024-12-06
3 NON SUBSTANTIAL MODIFICATION NSM-1 2024-12-26 Portugal Acceptable 2024-12-26