The Neurobiological Effect of 5-HT2AR Modulation

2024-515961-33-00 Protocol 2016-004000-61 Human pharmacology (Phase I) - Other Ongoing, recruiting

Start 2 Sep 2024 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol 2016-004000-61

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ongoing, recruiting
Participants planned 240
Countries 1
Sites 1

No medical conditions or diseases will be examined, only healthy volunteers will participate.

Key facts

Sponsor
Rigshospitalet
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Investigative Techniques [E05]
Trial duration
2 Sep 2024 → ongoing
Decision date (initial)
2024-09-02
Transition trial
Yes
Low-intervention
No
Rare-disease indication
No
Vulnerable population
Yes

External identifiers

EU CT number
2024-515961-33-00
EudraCT number
2016-004000-61
ClinicalTrials.gov
NCT03289949

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

No medical conditions or diseases will be examined, only healthy volunteers will participate.

VersionLevelCodeTermSystem organ class
22.0 SOC 10022891 Investigations 23
22.1 PT 10061944 Brain scan normal 100000004848

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Rigshospitalet

Sponsor organisation
Rigshospitalet
Address
Blegdamsvej 9
City
Copenhagen Oe
Postcode
2100
Country
Denmark

Scientific contact point

Organisation
Rigshospitalet
Contact name
Gitte Moos Knudsen

Public contact point

Organisation
Rigshospitalet
Contact name
Gitte Moos Knudsen

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Denmark Ongoing, recruiting 240 1
Rest of world 0

Investigational sites

Denmark

1 site · Ongoing, recruiting
Rigshospitalet
Neurobiology Research Unit, Blegdamsvej 9, 2100, Copenhagen Oe

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Denmark 2024-09-02 2024-09-02

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-08-13 Denmark Acceptable
2024-09-02
2024-09-02
2 SUBSTANTIAL MODIFICATION SM-2 2025-11-28 Denmark Acceptable
2025-12-12
2025-12-12