A clinical study of MK-4646 in healthy people (MK-4646-002)

2024-516626-63-00 Protocol MK-4646-002 Human pharmacology (Phase I) - Other Ended

Start 18 Nov 2024 · End 12 Apr 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol MK-4646-002

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 32
Countries 1
Sites 1

HIV infection

Key facts

Sponsor
Merck Sharp & Dohme LLC
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
18 Nov 2024 → 12 Apr 2025
Decision date (initial)
2024-11-18
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

External identifiers

EU CT number
2024-516626-63-00
WHO UTN
U1111-1310-8691

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

HIV infection

VersionLevelCodeTermSystem organ class
20.1 PT 10000807 Acute HIV infection 100000004862

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Merck Sharp & Dohme LLC

Sponsor organisation
Merck Sharp & Dohme LLC
Address
126 East Lincoln Avenue, P. O. Box 2000 P. O. Box 2000
City
Rahway
Postcode
07065-4607
Country
United States

Scientific contact point

Organisation
Merck Sharp & Dohme LLC
Contact name
Russ Carstens

Public contact point

Organisation
Merck Sharp & Dohme LLC
Contact name
Russ Carstens

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Belgium Ended 32 1
Rest of world 0

Investigational sites

Belgium

1 site · Ended
Universitair Ziekenhuis Gent
DRUG, Corneel Heymanslaan 10, 9000, Gent

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Belgium 2024-11-18 2025-04-11 2024-11-22 2025-04-02

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-09-27 Belgium Acceptable
2024-11-12
2024-11-18