Bioequivalence of two transdermal therapeutic systems delivering 100 mcg/h fentanyl

2024-517506-29-00 Protocol CLP24001 Human pharmacology (Phase I) - Bioequivalence study Authorised, recruitment pending

Status Authorised, recruitment pending · 1 EU/EEA countries · 1 sites · Protocol CLP24001

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Bioequivalence study
Status Authorised, recruitment pending
Participants planned 30
Countries 1
Sites 1

Bioequivalence trial in healthy volunteers

Key facts

Sponsor
CCDRD Cooperative Clinical Drug Research and Development AG, Lavipharm S.A.
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Male and Female
Therapeutic area
Diseases [C] - Pathological Conditions, Signs and Symptoms [C23]
Decision date (initial)
2025-04-03
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Bioequivalence trial in healthy volunteers

VersionLevelCodeTermSystem organ class
20.0 PT 10056350 Pain management 100000004865

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

CCDRD Cooperative Clinical Drug Research and Development AG

Sponsor organisation
CCDRD Cooperative Clinical Drug Research and Development AG
Address
Dahlwitz, Lindenallee 70, Dahlwitz-Hoppegarten Lindenallee 70 Dahlwitz-Hoppegarten
City
Hoppegarten
Postcode
15366
Country
Germany

Scientific contact point

Organisation
Lavipharm S.A.
Contact name
Lavipharm S.A. R&D Director: Panaitescu Ligia

Public contact point

Organisation
Lavipharm S.A.
Contact name
Lavipharm S.A. R&D Director: Panaitescu Ligia

Lavipharm S.A.

Sponsor organisation
Lavipharm S.A.
Address
Agias Marinas Street, P. O. Box 59 P. O. Box 59
City
Peania
Postcode
19002
Country
Greece

Scientific contact point

Organisation
Lavipharm S.A.
Contact name
R&D Director: Ligia Panaitescu

Public contact point

Organisation
Lavipharm S.A.
Contact name
R&D Director: Ligia Panaitescu

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Bulgaria Authorised, recruitment pending 30 1
Rest of world 0

Investigational sites

Bulgaria

1 site · Authorised, recruitment pending
Multidisciplinary Hospital for Active Treatment (MHAT) Evropa OOD
Department of gastroenterology, 2, Pencho Slaveikov Str., Sofia

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-12-19 Bulgaria Acceptable
2025-04-02
2025-04-03
2 NON SUBSTANTIAL MODIFICATION NSM-1 2025-04-15 Bulgaria Acceptable
2025-04-02
2025-04-15