A study to determine the safety and effect of antibodies against hepatitis D (the SAMBA-D study)

2025-522125-36-00 Protocol SAMBA-D-001 Human pharmacology (Phase I) - Other Authorised, recruiting

Start 22 Apr 2026 · Status Authorised, recruiting · 2 EU/EEA countries · 7 sites · Protocol SAMBA-D-001

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Authorised, recruiting
Participants planned 15
Countries 2
Sites 7

Chronic hepatitis D infection

Key facts

Sponsor
Region Midtjylland
Participant type
Patients
Age range
18-64 years, 65+ years
Gender
Male and Female
Therapeutic area
Diseases [C] - Virus Diseases [C02]
Trial duration
22 Apr 2026 → ongoing
Decision date (initial)
2026-01-19
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Chronic hepatitis D infection

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Region Midtjylland

Sponsor organisation
Region Midtjylland
Address
Palle Juul-Jensens Boulevard 99
City
Aarhus N
Postcode
8200
Country
Denmark

Scientific contact point

Organisation
Region Midtjylland
Contact name
Department of Infectious Diseases

Public contact point

Organisation
Region Midtjylland
Contact name
Department of Infectious Diseases

Locations

2 EU/EEA countries · 7 investigational sites

By country

CountryMS statusPlanned subjectsSites
Denmark Ongoing, recruiting 7 6
Germany Authorised, recruitment pending 8 1
Rest of world 0

Investigational sites

Denmark

6 sites · Ongoing, recruiting
Kolding Sygehus
Infectious Diseases, Sygehusvej 24, 6000, Kolding
Hvidovre Hospital
Infectious Diseases, Kettegaard Alle 36, 2650, Hvidovre
Rigshospitalet
Infectious Diseases, Blegdamsvej 9, 2100, Copenhagen Oe
Odense University Hospital
Infectious Diseases, Kloevervaenget 47, 5000, Odense C
Region Midtjylland
Infectious Diseases, Palle Juul-Jensens Boulevard 99, 8200, Aarhus N
Aalborg University Hospital
Infectious Diseases, Moelleparkvej 4, 9000, Aalborg

Germany

1 site · Authorised, recruitment pending
Charite Universitaetsmedizin Berlin KöR
Infectious Diseases, Augustenburger Platz 1, Wedding, Berlin

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Denmark 2026-04-22 2026-04-23

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-09-11 Denmark Acceptable
2026-01-19
2026-01-19
2 NON SUBSTANTIAL MODIFICATION NSM-1 2026-04-24 Denmark Acceptable
2026-01-19
2026-04-24