To evaluate the pharmacokinetics and safety of nolasiban

2025-523706-32-00 Protocol RPN-NLS01 Human pharmacology (Phase I) - Other Ongoing, recruiting

Start 17 Feb 2026 · Status Ongoing, recruiting · 1 EU/EEA countries · 1 sites · Protocol RPN-NLS01

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ongoing, recruiting
Participants planned 28
Countries 1
Sites 1

not applicable (submitted trial is a pharmacokinetic study in healthy subjects)

Key facts

Sponsor
ReproNovo ApS
Participant type
Healthy volunteers
Age range
18-64 years
Gender
Female
Therapeutic area
Diseases [C] - Female Urogenital Diseases and Pregnancy Complications [C13]
Trial duration
17 Feb 2026 → ongoing
Decision date (initial)
2026-01-09
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

not applicable (submitted trial is a pharmacokinetic study in healthy subjects)

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

ReproNovo ApS

Sponsor organisation
ReproNovo ApS
Address
Amagerfaelledvej 106
City
Copenhagen S
Postcode
2300
Country
Denmark

Scientific contact point

Organisation
ReproNovo ApS
Contact name
ReproNovo Aps (contact)

Public contact point

Organisation
ReproNovo ApS
Contact name
ReproNovo Aps (contact)

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Czechia Ongoing, recruiting 28 1
Rest of world 0

Investigational sites

Czechia

1 site · Ongoing, recruiting
Quinta-Analytica s.r.o.
Clinical Unit, Prazska 1486/18c, Hostivar, Prague

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Czechia 2026-02-17 2026-02-17

Application history

2 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2025-11-18 Czechia Acceptable
2026-01-09
2026-01-09
2 NON SUBSTANTIAL MODIFICATION NSM-1 2026-05-21 Czechia Acceptable
2026-01-09
2026-05-21