Methotrexate Sodium — Drug Intelligence | 10 EU Trials

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10 Registered trials

4 Recruiting

4 Completed trials

9 Sponsors

21 Countries

Phase III

Phase II/III

Phase II

Phase IV

Phase III: 3 Phase II/III: 1 Phase II: 4 Phase IV: 2

Oversight events:

1 serious breach across 1 trial

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Indications tested

Anti-neutrophil cytoplasmic antibody positive vasculitis 1 Rheumatoid arthritis 1 Myasthenia gravis 1

Sponsors using this IMP

Amgen Inc. 2 Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia 1 Centre Hospitalier Universitaire De Bordeaux 1 Genentech Inc. 1 Karolinska Institutet 1 Kyverna Therapeutics Inc. 1 Ospedale Galeazzi S.p.A. 1 Universitaetsklinikum Muenster AöR 1 Universitaetsklinikum Schleswig-Holstein 1

All trials

10 total

A multicenter, randomized, open-label, blinded-assessor, phase 4 study in patients with early rheumatoid arthritis to compare active convent… Pending

2024-516723-14-00 Phase IV 4 countries Karolinska Institutet
Prospective Phase II study on Safety and Efficacy of Fludarabine plus Treosulfan (14g) (FT14) conditioning regimen for allogeneic Stem Cell … Pending

2024-520326-11-00 Phase II 1 country Azienda Socio Sanitaria Territoriale Degli Spedali Civili Di Brescia
Trial to Evaluate the Long-term Safety and Efficacy of Avacopan in participants With ANCA-associated Vasculitis Recruiting

2023-503184-42-00 Phase IV 7 countries Amgen Inc.
“The BAPTIST study” Baricitinib in calcium pyrophosphAte dePosiTion dIseaSe Trial – a proof of concept phase II clinical trial . Recruiting

2024-511864-95-00 Phase II 1 country Ospedale Galeazzi S.p.A.
A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy, in Subjects With Generalized Myasthenia Gravis Recruiting

2023-509892-17-00 Phase II/III 1 country Kyverna Therapeutics Inc.
LBL 2018 - International cooperative treatment protocol for children and adolescents with lymphoblastic lymphoma Recruiting

2023-508101-24-00 Phase III 14 countries Universitaetsklinikum Muenster AöR
A Randomized Study Comparing Blinatumomab Alternating With Low-intensity Chemotherapy Versus Standard of Care Chemotherapy for Older Adults … Ended

2023-503640-14-00 Phase III 17 countries Amgen Inc.
AIEOP-BFM ALL 2017 - International collaborative treatment protocol for children and adolescents with acute lymphoblastic leukemia Ended

2023-509856-32-00 Phase III 5 countries Universitaetsklinikum Schleswig-Holstein
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants with Moderate to Severe Ulcerative Colitis Ended

2023-506655-19-00 Phase II 7 countries Genentech Inc.
This is a phase 2, randomized, double blind, multicenter study evaluating the efficacy and safety of the combination of methotrexate plus UV… Ended

2024-512766-34-00 Phase II 1 country Centre Hospitalier Universitaire De Bordeaux

Showing 1–10 of 10 trials

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