Karolinska Institutet — Sponsor Intelligence | 27 EU Trials

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27 Registered trials

9 Recruiting

6 Completed trials

7 Countries active

58 Unique IMPs

100% Results reported

Phase III

Phase II

Phase I/II

Phase IV

Phase III: 6 Phase II/III: 1 Phase II: 9 Phase I/II: 3 Phase III/IV: 1 Phase IV: 5 Phase I: 2

Oversight events:

5 temporary halts across 3 trials

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100%

6 of 6 completed trials have published summary results (EU CTR Article 37 — 12-month obligation).

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Top indications

Rheumatoid arthritis 1 Acute myocardial infarction 1 Congo-Crimean haemorrhagic fever 1 Prostate cancer metastatic 1 Chronic kidney disease 1 Breast cancer female 1 Ischaemic stroke 1 Rhinitis allergic 1 Allergic respiratory disease 1 Glioblastoma multiforme 1

Top IMPs

ACETYLSALICYLIC ACID 1 ALLOGENEIC FETAL MESENCHYMAL STEM CELLS 1 AMOXICILLIN 1 APIXABAN 1 CANIS FAMILIARIS (553) 1 CAPIVASERTIB 1 CERTOLIZUMAB PEGOL 1 CYCLOPHOSPHAMIDE 1 DAROLUTAMIDE 1 DESLORATADINE 1 DOCETAXEL 1 DOXORUBICIN HYDROCHLORIDE 1

All trials

27 total

Early intervention and recovery of sexual function in men and women after treatment of rectal cancer–a randomized placebo-controlled study w… Pending

2023-504592-24-00 Phase II 1 country TADALAFIL
A Clinical Trial Evaluating the Efficacy of Valganciclovir in Glioblastoma Patients Pending

2023-504846-73-01 Phase II 2 countries
ALASCCA-A randomized double-blind placebo-controlled study with ASA treatment in colorectal cancer patients with mutations in the PI3K signa… Pending

2024-513778-23-00 Phase III 4 countries ACETYLSALICYLIC ACID
Dose monitoring of commonly used cytostatic drugs for breast cancer Pending

2024-514818-12-00 Phase IV 1 country CYCLOPHOSPHAMIDE; DOCETAXEL; DOXORUBICIN HYDROCHLORIDE; EPIRUBICIN HYDROCHLORIDE…
A multicenter, randomized, open-label, blinded-assessor, phase 4 study in patients with early rheumatoid arthritis to compare active convent… Pending

2024-516723-14-00 Phase IV 4 countries CERTOLIZUMAB PEGOL; TOCILIZUMAB; TRIAMCINOLONE HEXACETONIDE
Immediate insertion of intrauterine contraception after medical abortion Pending

2024-517082-16-01 Phase III 1 country LEVONORGESTREL
CAT-01 Pending

2024-517594-24-01 Phase I/II 1 country
Evaluation of Allergen Specific Vaccination of Dog Allergic Patients in Swedish Practice Pending

2024-517649-15-00 Phase IV 1 country CANIS FAMILIARIS (553); DESLORATADINE; LEVOCABASTINE HYDROCHLORIDE; MOMETASONE F…
A randomized controlled trial of the effect of anesthetic dose during electroconvulsive therapy for major depression Pending

2024-519407-99-00 Phase IV 1 country THIOPENTAL SODIUM
RISE Pending

2024-520141-23-01 Phase III 1 country
Swedish Cardiac And Renal Failure study-1 (SCARF-1): An open-label pilot trial to evaluate the feasibility, safety and efficacy of eplerenon… Pending

2025-520550-11-00 Phase II 1 country
AdaptNK –Cell Therapy for High-risk Myeloid Disease Pending

2025-521962-83-00 Phase I/II 1 country
A positron emission tomography study of synaptic nerve cells proteins alpha-7 nicotinic acetylcholine receptors in brain of healthy voluntee… Recruiting

2024-515935-31-04 Phase I 1 country
The POWER trial: A randomised, two-armed open label phase 3 clinical trial on personalised dose optimisation with adjuvant tamoxifen therapy… Recruiting

2025-522240-40-00 Phase III 1 country TAMOXIFEN
RandomizEd compariSOn of apixaban versus warfarin in patients with Left VEntricular thrombus after Acute Myocardial Infarction (RESOLVE-AMI)… Recruiting

2024-514416-28-00 Phase IV 2 countries APIXABAN; PERFLUTREN; SULFUR HEXAFLUORIDE; WARFARIN SODIUM
The effect of acupuncture or metformin for improvement of insulin sensitivity in women with Polycystic Ovary Syndrome Recruiting

2024-514505-64-01 Phase III/IV 1 country METFORMIN HYDROCHLORIDE
Effects by botulinum toxin in patients with jaw muscle pain Recruiting

2024-514739-12-00 Phase II 1 country
Mifepristone and Letrozole in Ectopic Pregnancy (MILE) Recruiting

2023-503935-16-00 Phase II 1 country LETROZOLE; METHOTREXATE; MIFEPRISTONE
Role of antibiotics in conjunction with oral bone augmentation procedures (BAS20) Recruiting

2024-517402-28-00 Phase II 1 country AMOXICILLIN; PHENOXYMETHYLPENICILLIN POTASSIUM
Mesalamine administration to prevent development of colorectal cancer in Lynch syndrome Recruiting

2024-514765-19-01 Phase II 2 countries MESALAZINE
ProBio: An outcome-adaptive and randomised multi-arm biomarker driven study in patients with metastatic prostate cancer Recruiting

2023-506857-40-00 Phase III 3 countries CAPIVASERTIB; DAROLUTAMIDE; NIRAPARIB, ABIRATERONE ACETATE
An open, randomised, controlled phase II trial of CellProtect in combination with Isatuximab antibody versus Isatuximab antibody alone as ma… Ended

2024-514527-42-00 Phase II 1 country EVENCALEUCEL; ISATUXIMAB
Intralymfatisk immunterapi förstärkt av vitamin-D, en randomiserad placebokontrollerad studie och jämförelse med SLIT Ended

2024-515271-35-00 Phase II/III 1 country PHLEUM PRATENSE (225); SODIUM CHLORIDE
Treatment of severe congenital Brittle bone disease after or before and after birth. Ended

2023-504593-38-00 Phase I/II 2 countries ALLOGENEIC FETAL MESENCHYMAL STEM CELLS

Showing 1–24 of 27 trials

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