42
Registered trials
26
Recruiting
31
Unique sponsors
39
Unique IMPs
37
Commercial trials
Drug classes (ATC)
—
ATC code not specified
31
L
Oncology (ATC L)
11
N
Neurology/Psychiatry (ATC N)
1
Mechanism of action (INN-stem analysis)
Unknown / small molecule
21 substances
Kinase inhibitor
3 substances
Monoclonal antibody (immune)
3 substances
Antibody-drug conjugate (ADC)
3 substances
Monoclonal antibody
2 substances
Antimetabolite
1 substance
Checkpoint inhibitor (PD-1)
1 substance
PARP inhibitor
1 substance
Anthracycline
1 substance
Taxane
1 substance
Monoclonal antibody (rat)
1 substance
Monoclonal antibody (tumor, humanized)
1 substance
Phase III:
8
Phase II:
13
Phase I/II:
3
Phase I:
10
Phase I (Other):
1
Phase I (First in Human):
7
Phase III
8 trials-
RecruitingAstraZeneca AB CommercialRILVEGOSTOMIG; TRASTUZUMAB DERUXTECAN
-
RecruitingAstraZeneca AB CommercialOLAPARIB
-
RecruitingBioNTech SE CommercialDB-1303; DOXORUBICIN HYDROCHLORIDE; PACLITAXEL
-
PendingGenmab A/S CommercialRINATABART SESUTECAN
-
EndedKaryopharm Therapeutics Inc. CommercialIMP not specified
-
RecruitingMerck Sharp & Dohme LLC CommercialBELZUTIFAN; LENVATINIB
-
EndedArcagy Gineco AcademicIMP not specified
-
EndedCentre Oscar Lambret AcademicIMP not specified
Phase II
13 trials-
RecruitingAcrivon Therapeutics Inc. CommercialGEMCITABINE; PREXASERTIB LACTATE MONOHYDRATE
-
RecruitingBayer Consumer Care AG Commercial3-(3-CHLORO-2-METHOXYANILINO)-2-{3-[(2S)-1,4-DIOXAN-2-YLMETHOXY]PYRIDIN-4-YL}-1,5,6,7-TETRAHYDRO-4H-PYRROLO[3,2-C]PYRIDIN-4-ONE; BAY 2927088; SEVABERTINIB
-
RecruitingCorcept Therapeutics Inc. CommercialRELACORILANT
-
EndedDaiichi Sankyo Inc. CommercialRALUDOTATUG DERUXTECAN
-
EndedF. Hoffmann-La Roche AG CommercialGIREDESTRANT
-
EndedGenmab A/S CommercialGEN1046; PEMBROLIZUMAB
-
EndedIncyte Corp. CommercialHUMAN IGG1K MONOCLONAL ANTIBODY AGAINST TIM-3; PEMIGATINIB; RETIFANLIMAB; TUPARSTOBART
-
RecruitingJazz Pharmaceuticals Ireland Limited CommercialZANIDATAMAB
-
RecruitingSeagen Inc. CommercialDISITAMAB VEDOTIN
-
RecruitingSichuan Kelun-Biotech Biopharmaceutical Co. Ltd. CommercialPEMBROLIZUMAB; SKB264
-
RecruitingGrupo Espanol De Investigacion En Cancer De Ovario AcademicDOSTARLIMAB
-
RecruitingUniversitair Medisch Centrum Groningen AcademicPEMBROLIZUMAB
-
RecruitingVall D Hebron Institute Of Oncology AcademicIMP not specified
Phase I/II
3 trials-
RecruitingDaiichi Sankyo Inc. CommercialIFINATAMAB DERUXTECAN
-
EndedEisai Limited CommercialFARLETUZUMAB ECTERIBULIN; LENVATINIB
-
RecruitingEisai Limited Commercial(6S,9AS)-8-((6-(3-(4-ETHYL-1-PIPERAZINYL)-1-AZETIDINYL)-2-PYRIDINYL)METHYL)-6-((2-FLUORO-4-HYDROXYPHENYL)METHYL)HEXAHYDRO-4,7-DIOXO-N-(PHENYLMETHYL)-2-(2-PROPEN-1-YL)-2H-PYRAZINO(2,1-C)(1,2,4)TRIAZINE-1(6H)-CARBOXAMIDE; DOXORUBICIN HYDROCHLORIDE; LENVATINIB; PACLITAXEL
Phase I
10 trials-
RecruitingBeOne Medicines AG CommercialIMP not specified
-
RecruitingBeOne Medicines AG CommercialIMP not specified
-
RecruitingBristol-Myers Squibb Services Unlimited Company CommercialIMP not specified
-
EndedCullinan Therapeutics Inc. CommercialIMP not specified
-
EndedIkena Oncology Inc. CommercialIMP not specified
-
RecruitingImmunocore Limited CommercialIMP not specified
-
EndedSeagen Inc. CommercialSGN-ALPV
-
EndedSeagen Inc. CommercialIMP not specified
-
RecruitingSeagen Inc. CommercialIMP not specified
-
RecruitingZymeworks Inc. CommercialIMP not specified
Phase I (Other)
1 trial-
EndedExelixis Inc. CommercialIMP not specified
Phase I (First in Human)
7 trials-
EndedBioNTech SE CommercialBNT142
-
RecruitingBioNTech SE CommercialBNT329
-
PendingCrescent Biopharma Inc. CommercialCR-001
-
RecruitingDaiichi Sankyo Inc. CommercialDS-3939A
-
RecruitingPmv Pharmaceuticals Inc. CommercialPC14586
-
RecruitingRegeneron Pharmaceuticals Inc. CommercialCEMIPLIMAB; SARILUMAB; UBAMATAMAB
-
RecruitingScorpion Therapeutics Inc. CommercialIMP not specified
Sponsor activity
| Sponsor | Type | Trials | Phases | Recruiting |
|---|---|---|---|---|
| Seagen Inc. | Commercial | 4 | Phase I, Phase II | 2 |
| Daiichi Sankyo Inc. | Commercial | 3 | Phase II, Phase I (First in Human), Phase I/II | 2 |
| BioNTech SE | Commercial | 3 | Phase III, Phase I (First in Human) | 2 |
| BeOne Medicines AG | Commercial | 2 | Phase I | 2 |
| Genmab A/S | Commercial | 2 | Phase II, Phase III | 0 |
| AstraZeneca AB | Commercial | 2 | Phase III | 2 |
| Eisai Limited | Commercial | 2 | Phase I/II | 1 |
| Bristol-Myers Squibb Services Unlimited Company | Commercial | 1 | Phase I | 1 |
| Cullinan Therapeutics Inc. | Commercial | 1 | Phase I | 0 |
| Ikena Oncology Inc. | Commercial | 1 | Phase I | 0 |
| Immunocore Limited | Commercial | 1 | Phase I | 1 |
| Zymeworks Inc. | Commercial | 1 | Phase I | 1 |
| Exelixis Inc. | Commercial | 1 | Phase I (Other) | 0 |
| Acrivon Therapeutics Inc. | Commercial | 1 | Phase II | 1 |
| Bayer Consumer Care AG | Commercial | 1 | Phase II | 1 |
| Corcept Therapeutics Inc. | Commercial | 1 | Phase II | 1 |
| F. Hoffmann-La Roche AG | Commercial | 1 | Phase II | 0 |
| Incyte Corp. | Commercial | 1 | Phase II | 0 |
| Jazz Pharmaceuticals Ireland Limited | Commercial | 1 | Phase II | 1 |
| Sichuan Kelun-Biotech Biopharmaceutical Co. Ltd. | Commercial | 1 | Phase II | 1 |
New trials by year
2020
1
2021
2
2022
5
2023
7
2024
7
2025
8
2026
7