Phase I – Other

1,064 trials 249 recruiting

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A study in subjects with gout flares that investigates the effect, safety, tolerability, and pharmacokinetics (absorption, distribution, met… Ended

2023-508793-29-00 Gout flares 2025-01-07
Characterisation of availability in the body of the active substance(s) of the newly developed patch Esflurbiprofen Topical System (EFTS) in… Ended

2024-513058-31-00 bioavailability and patch adhesion trial with healthy v 2025-01-07
A clinical study of MK-6916 in healthy people (MK-6916-002) Ended

2024-516899-15-00 Acute and Chronic Pain 2025-01-07
A drug-drug interaction trial in healthy female participants to investigate the effect of aprocitentan on combined hormonal contraceptives. Ended

2024-517224-19-00 Not applicable - healthy volunteer trial 2025-01-06
Mass balance study of [14C]-VAD044 Ended

2024-518843-39-00 Vascular malformation 2024-12-31
A Phase I, Open-Label, Randomized, Two-Period, Cross-Over Study in Healthy Subjects to Assess the Influence of a High-Calorie, High-Fat Meal… Ended

2024-518453-41-00 Hereditary angioedema (HAE) 2024-12-30
A Trial Comparing Pharmacokinetics, Safety and Tolerability of Two Subcutaneous Concentrations of Dapiglutide Ended

2024-516901-21-00 Weight management 2024-12-23
Study to compare drug availability in bloodstream of two oral formulations of mesalazine in healthy volunteers under fed conditions. Ended

2024-517107-37-00 Chronic idiopathic inflammatory bowel disease 2024-12-20
A clinical study of MK-2420 in healthy men (MK-2420-003) Ended

2024-518104-47-00 Rheumatoid arthritis 2024-12-19
A study to compare two different aramchol formulations in healthy volunteers. Ended

2023-507445-28-00 Nonalcoholic fatty liver disease 2024-12-18
An open-label, randomised, single-dose, three-way cross-over trial to assess the pharmacokinetics of NIC24-01 and NIC24-02 oromucosal pouche… Ended

2024-514676-40-00 Nicotine dependence 2024-12-12
A Study to evaluate the effect of a high-fat meal on the Pharmacokinetics of the Selective MET kinase Inhibitor DO-2 in subjects in good hea… Ended

2024-518581-27-00 Healthy volunteer 2024-12-12
A study to find how well VES001 works and how safe it is in participants with GRN -frontotemporal dementia (GRN-FTD) showing no symptoms Ended

2024-513258-31-00 Frontotemporal dementia (FTD) 2024-12-11
A study to test how different doses of BI 3731579 are tolerated by healthy people Ended

2024-517209-95-00 Healthy volunteer trial 2024-12-11
A clinical study of MK-6916 and placebo in healthy people (MK-6916-003) Ended

2024-516878-30-00 Acute and chronic Pain 2024-12-10
A PHASE I, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE ASCENDING, SINGLE-DOSE STUDY TO EVALUATE SAFETY, TOLERABILITY, PHARMACOKINETIC… Ended

2024-515151-38-00 Nervous System disease 2024-12-06
A study to assess the effects of efgartigimod on emasiprubart in healthy adult participants Ended

2024-517511-70-00 not applicable 2024-12-04
A Phase I Open-Label, Dose-escalation Clinical Trial of Tumor Necrosis Factor Alpha and Interleukin-2 Coding Oncolytic Adenovirus TILT-123 i… Ended

2024-518088-37-01 Melanoma, SCCHN 2024-12-04
Study to evaluate food effect on the pharmacokinetics of mesalazine oral formulation in healthy volunteers. Ended

2024-514748-10-00 Ulcerative colitis 2024-11-28
An open-label, multicentric, phase I study with expansion cohorts, evaluating the safety and the efficacy of combination of atezolizumab, ti… Ended

2024-516717-20-00 Metastatic non small cell lung cancer (Phase I and expa 2024-11-27
A study investigating the effect of different approved medications on how the body processes the study compound RO7795081. RO7795081 is a ne… Ended

2024-517360-37-00 Type 2 Diabetes and obesity 2024-11-22
An open-label, DDI study to investigate the effects of amlitelimab on the PK of selected cytochrome P450 substrates Ended

2024-513495-17-00 Dermatitis atopic 2024-11-20
A Study to Learn About How Different Formulations of the Medicine Called Mevrometostat are Taken up Into the Blood in Healthy Adult Particip… Ended

2024-516907-18-00 Small cell lung cancer, Castration-resistant prostate c 2024-11-20
A Phase 1, multiple-dose, single-center, randomized, open-label, 2-period, 2-treatment crossover systemic bioavailability study of diclofena… Ended

2024-515954-26-00 Phase I Study in healthy male and female volunteers. In 2024-11-19