A drug-drug interaction trial in healthy female participants to investigate the effect of aprocitentan on combined hormonal contraceptives.

2024-517224-19-00 Protocol ID-080-111 Human pharmacology (Phase I) - Other Ended

Start 6 Jan 2025 · End 22 Feb 2025 · Status Ended · 1 EU/EEA countries · 1 sites · Protocol ID-080-111

Overview

Sponsor-declared trial summary

Phase Human pharmacology (Phase I) - Other
Status Ended
Participants planned 19
Countries 1
Sites 1

Not applicable - healthy volunteer trial

Key facts

Sponsor
Idorsia Pharmaceuticals Ltd.
Participant type
Healthy volunteers
Age range
18-64 years, 65+ years
Gender
Female
Therapeutic area
Not possible to specify
Trial duration
6 Jan 2025 → 22 Feb 2025
Decision date (initial)
2024-12-10
Transition trial
No
Low-intervention
No
Rare-disease indication
No
Vulnerable population
No

Trial design

CTIS Part I — objectives, methods, condition coding

Conditions and MedDRA coding

Not applicable - healthy volunteer trial

Sponsors and contacts

Sponsor organisations, regulatory contacts, third parties

Idorsia Pharmaceuticals Ltd.

Sponsor organisation
Idorsia Pharmaceuticals Ltd.
Address
Hegenheimermattweg 91
City
Allschwil
Postcode
4123
Country
Switzerland

Scientific contact point

Organisation
Idorsia Pharmaceuticals Ltd.
Contact name
Idorsia Clinical Trials Information

Public contact point

Organisation
Idorsia Pharmaceuticals Ltd.
Contact name
Idorsia Clinical Trials Information

Locations

1 EU/EEA country · 1 investigational sites

By country

CountryMS statusPlanned subjectsSites
Czechia Ended 19 1
Rest of world 0

Investigational sites

Czechia

1 site · Ended
Cepha s.r.o.
CEPHA, Komenskeho 19, Severni Predmesti, Plzen 1

Country notifications

Trial-start, recruitment-start, end and early-termination notifications submitted per Member State

Country Trial startTrial end Recruitment startRecruitment end Early termination
Czechia 2025-01-06 2025-02-21 2025-01-06 2025-01-18

Application history

1 submissions — initial application plus substantial / non-substantial modifications

#TypeCodeSubmittedReference MSConclusionDecision date
1 INITIAL IN 2024-09-25 Czechia Acceptable
2024-12-06
2024-12-10