Phase I – Other

1,064 trials 249 recruiting

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A Study to Learn About if the Study Medicine Called Ibuzatrelvir changes how the body process the other Medicine Dabigatran Etexilate in hea… Ended

2024-517797-14-00 severe acute respiratory syndrome coronavirus 2 (SARS-C 2024-11-19
A Study to Investigate the Pharmacokinetics, Safety and Tolerability of AZD5462 in Participants with Renal Impairment Ended

2024-514359-14-00 Impaired renal function 2024-11-18
A clinical study of MK-4646 in healthy people (MK-4646-002) Ended

2024-516626-63-00 HIV infection 2024-11-18
Evaluation of the CHF 5993 concentration in blood, after inhalation with two different devices, (NEXThaler® versus pMDI), with and without A… Ended

2024-512792-13-00 Asthma 2024-11-13
A study in healthy people to test how 2 different formulations of BI 690517 are taken up in the body and how probenecid influences the amoun… Ended

2024-513590-45-00 Healthy volunteer trial 2024-11-12
A study of the safety, absorption and effects of investigational drug ARV-102 in patients with Parkinson's disease. Ended

2024-516888-84-00 Parkinson's disease. 2024-11-12
A Single Dose, Non-randomised, Open-label, Parallel Group Study to Assess the Pharmacokinetics, Safety, and Tolerability of AZD4144 in Parti… Ended

2024-513848-28-00 Healthy Volunteers 2024-11-11
A Randomized, Placebo-Controlled, Double-Blind, Single Dose, Phase 1 Study to Explore the PK/PD Relationship of QRL-101 in People Living Wit… Ended

2024-515021-29-00 Amyotrophic lateral sclerosis (ALS) 2024-11-11
AMEND - Add-on MEmaNtine to Dopamine modulation to improve negative symptoms at first psychosis Ended

2024-513878-21-02 First episode psychosis; ICD-10: F20.x; F22.x; F23.x; F 2024-11-11
A study to assess the effect of gemfibrozil, itraconazole and phenytoin on levels of IPN60250 in the blood of healthy adult participant. Ended

2024-513891-16-00 Not applicable 2024-11-08
A study in healthy men to test whether BI 1815368 influences the amount of metformin in the body Ended

2024-515911-23-00 Healthy volunteer trial 2024-11-06
Effects of DLX-001 on PD, Safety, Tolerability, and PK in Participants with MDD Ended

2024-517139-29-00 Major Depressive Disorder (MDD) 2024-11-06
A clinical study of MK-3508 in healthy people (MK-3508-006) Ended

2024-516619-26-00 Respiratory syncytial virus infection 2024-11-04
A study to learn more about how BAY3283142 moves into, through, and out of the body of healthy participants when taken together with atazana… Ended

2024-510856-11-00 Chronic kidney disease 2024-10-31
An Early Phase Study to Investigate the Safety and Efficacy of HS135 in Adult Patients With Pulmonary Arterial Hypertension (PAH) Ended

2023-510452-23-00 Pulmonary arterial hypertension 2024-10-29
A clinical study of MK-1403 in healthy men (MK-1403-004) Ended

2024-514629-52-00 Atherosclerosis 2024-10-28
A Phase I Study Using Hepatic Arterial Infusion of Autologous Tumor Infiltrating Lymphocytes in Patients with Melanoma and Liver Metastases Ended

2024-512877-28-00 Metastases to liver 2024-10-23
A study in healthy people to test how 2 different doses of BI 1291583 are taken up in the body when given in 3 different formulations. Ended

2023-510260-13-00 Healthy volunteer trial 2024-10-21
The ENERGY Study: Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INZ-701 in Infants with ENPP1 Deficiency… Ended

2023-507384-20-00 Ectonucleotide Pyrophosphatase/Phosphodiesterase 1 (ENP 2024-10-21
A Phase 1b study of inhaled RCT1100 in Adults with Primary Ciliary Dyskinesia Caused by Pathogenic Mutations in the DNAI1 Gene to Measure Mu… Ended

2023-510521-14-00 Adults with Primary Ciliary Dyskinesia 2024-10-18
A study investigating the safety, absorption, and elimination of radioactively labeled RO7269162, a new compound that may potentially be use… Ended

2024-513234-37-00 Healthy males volunteers 2024-10-16
ImmunoTHerapy Adjacent to Cervical CAncer (ITHACA) study: safety, toxicity and immunological effects of peritumorally delivered immunotherap… Ended

2023-505968-11-00 Cervical Cancer 2024-10-15
A Phase 1b, Double-blind, Placebo-controlled, Randomised Trial Investigating the Effect of AZD3427 on Renal Perfusion in HFrEF Patients With… Ended

2024-513143-82-00 Heart failure with reduced ejection fraction 2024-10-15
A Study to Learn how Various Tablets of the Study Medicine Called Vepdegestrant are Taken up into the Blood in Healthy Adults Ended

2024-514169-21-00 ER+/HER2- Breast Cancer 2024-10-11