Phase II/III (Integrated)

392 trials 186 recruiting

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A Study of the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Crohn's Disease Ended

2023-504736-18-00 Moderately to Severely Active Crohn's Disease 2018-07-26
A Study of Relatlimab plus Nivolumab Versus Nivolumab Alone in Participants with Advanced Melanoma Ended

2024-510913-13-00 Previously Untreated Metastatic or Unresectable Melanom 2018-05-18
Phase II umbrella study of novel anti-cancer agents in patients with NSCLC who progressed on an anti-PD-1/PD-L1 containing therapy. Ended

2023-509004-15-00 Patients with non-small cell lung cancer (NSCLC). 2018-02-20
ENRICH - Randomised, open label study of Rituximab/Ibrutinib vs Rituximab/Chemotherapy in older patients with untreated mantle cell lymphoma Ended

2024-514275-18-00 Mantle Cell Lymphoma (MCL) 2017-12-06
A Study Evaluating the Efficacy and Safety of Multiple Targeted Therapies as Treatments for Patients with Advanced or Metastatic Non-Small C… Ended

2023-507500-31-00 Advanced or metastatic Non-small cell lung cancer (NSCL 2017-08-22
STAR-TREC: Can we Save the rectum by watchful waiting or TransAnal surgery following (chemo)Radiotherapy versus Total mesorectal excision fo… Ended

2024-516106-31-00 Early stage colorectal cancer 2017-06-16
Study to Evaluate Imetelstat (GRN163L) in Subjects with IPSS Low or Intermediate-1 Risk Myelodysplastic Syndrome (MDS) Ended

2024-511348-25-00 Myelodysplastic syndromes (MDS) 2015-12-11
A clinical research study comparing two cisplatin dosing schedules combined with radiation for patients with advanced head and neck cancer. Halted

2024-515237-15-00 Advanced head and neck cancer 2025-01-21
A phase II/III multi-centre, open-label, parallel group study to prove the non-inferiority of safety and efficacy of Metronidazole/Neomycin … Halted

2024-518862-28-00 female patients with bacterial vaginosis (BV), respecti 2024-11-19
A Phase 2/3 Study in Adult and Pediatric Participants with SCD Suspended

2023-508766-14-00 Sickle Cell Disease
CD8 PET imaging study before and after CAR T-cell therapy Ended

2025-520560-18-00 Large B-cell lymphoma 2026-05-22
Safety, Efficacy, and Pharmacokinetics of CSL889 in Adults and Adolescents with Sickle Cell Disease during Vaso-Occlusive Crisis Ended

2024-513440-29-00 Sickle cell disease vaso-occlusive crisis 2025-06-25
Phase II-III study to assess the efficacy and safety of subcutaneous cluster-immunotherapy in patients suffering from house dust mite allerg… Ended

2024-517014-15-00 Moderate-to-severe allergic rhinitis / rhino-conjunctiv 2025-05-07
Study of Oral Weekly GS-1720 and GS-4182 Compared With Biktarvy in People With HIV-1 Who Have Not Been Treated Ended

2024-512505-66-00 HIV-1 Infection 2025-03-03
A Double-Blind, Randomized, Multicenter, Trial Evaluating the Efficacy and Safety of PRAX-628 in Adults with Focal Seizures (POWER 1) Ended

2024-514559-13-00 Focal Epilepsy 2024-11-26
Efficacy, Safety and Tolerability of BHV-7000 in Subjects with Idiopathic Generalized Epilepsy with Generalized Tonic-clonic Seizures – SHIN… Ended

2023-508812-45-00 Idiopathic Generalized Epilepsy with Generalized Tonic- 2024-11-11
Cannabidiol for treatment of non-affective psychosis and cannabis use Ended

2024-517630-18-00 Lifetime cannabis use 2024-10-08
Multicenter, Prospective, Open-label, Randomized, Crossover Study to Evaluate Pharmacokinetics (PK), Safety, and Tolerability of TAK-881 in … Ended

2022-502095-23-01 Primary Immunodeficiency Diseases 2024-09-10
Phase II-III study to assess the efficacy and safety of subcutaneous cluster-immunotherapy in patients suffering from Olea europaea pollen a… Ended

2024-511383-88-00 Moderate-to-severe allergic rhinitis / rhinoconjunctivi 2024-09-01
A randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the efficacy and safety of PLN-74809 (bexotegrast) for the tr… Ended

2023-506185-31-00 Idiopathic pulmonary fibrosis (IPF) 2024-07-18
FDG-PET/CT versus conventional CT for response monitoring in metastatic breast cancer: A pilot study for a randomized clinical trial (MONITO… Ended

2023-506550-20-00 Metastatic breast cancer 2024-07-05
A study to test long-term treatment with spesolimab in people with a skin condition disease called hidradenitis suppurativa (HS) who took pa… Ended

2023-508377-82-00 Hidradenitis Suppurativa (HS) 2024-06-27
Clinical trial of V940 and pembrolizumab in people with resectable locally advanced cutaneous squamous cell carcinoma Ended

2023-505712-37-00 The participants must have a histologically confirmed d 2024-06-06
A randomized, open label, multicenter phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic, refractory col… Ended

2023-509771-17-00 Metastatic Colorectal cancer (mCRC) 2024-06-04