Phase II/III (Integrated)

392 trials 186 recruiting

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A study to test the safety of MK-1654 and how well MK-1654 works in healthy infants Ended

2022-500350-42-01 Prevention of RSV 2022-11-07
A multiple ascending dose (MAD) safety, tolerability and efficacy study of VRDN-001, a humanized monoclonal antibody directed against the IG… Ended

2024-512244-36-00 Thyroid eye disease (TED) 2022-10-25
A phase 2/3 study to evaluate efficacy and clinical benefit of AT-007 with Sorbitol Dehydrogenase (SORD) Deficiency Ended

2024-518250-16-00 Sorbitol Dehydrogenase (SORD) Deficiency 2022-10-20
Nivolumab during active surveillance after neoadjuvant chemoradiation for esophageal cancer: SANO-3 study Ended

2024-513635-24-00 oesophageal cancer 2022-09-29
A Phase 2/3 Double-masked, Randomized, 2-stage, Multicenter Study of the Efficacy and Safety of OCS-01 Eye Drops in Subjects With Diabetic M… Ended

2023-507208-30-00 Diabetic Macular Edema (DME) 2022-09-20
A multicenter, randomized, open-label, blinded endpoint evaluation, phase 3 study comparing the effect of abelacimab relative to dalteparin … Ended

2024-513992-42-00 venous thromboembolism (VTE) in patients with gastroint 2022-09-13
A multicenter, randomized, open-label, blinded endpoint evaluation, phase 3 study comparing the effect of abelacimab relative to apixaban on… Ended

2023-509569-19-00 venous thromboembolism (VTE) 2022-08-10
Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial (IMPAHCT) or A Phase 2b/3, Randomized, Controlled, 24-week Dose Ranging and … Ended

2023-508734-34-00 Pulmonary Arterial Hypertension (PAH) 2022-06-30
A phase 2/3 study of efgartigimod PH20 SC in adult participants with bullous pemphigoid Ended

2023-508645-40-00 Bullous Pemphigoid (BP) 2022-05-10
A study to evaluate efficacy, safety and tolerability, pharmacokinetics and pharmacodynamics of emapalumab in children and adults with macro… Ended

2024-516153-52-00 Macrophage activation syndrome (MAS) in the context of 2022-03-28
Brightline-1: A study to compare brigimadlin (BI 907828) with doxorubicin in people with a type of cancer called dedifferentiated liposarcom… Ended

2024-511361-11-00 Advanced dedifferentiated liposarcoma 2022-03-25
A study to learn if brivaracetam works and is safe in children and young adults 2 to 25 years of age with childhood absence epilepsy or juve… Ended

2023-510428-55-00 Childhood Absence Epilepsy Juvenile Absence Epilepsy 2022-03-10
A multi-center interventional study to assess pharmacokinetics, effectiveness and tolerability of prolonged-release Tacrolimus after Paediat… Ended

2024-516608-40-00 Caucasian paediatric kidney transplant recipients 2022-02-23
Lidocaine in Liver Surgery Ended

2023-508173-90-00 Patients with liver tumours that have liver surgery per 2021-11-15
Preoperative intraperitoneal chemotherapy in adjuvant hyperthermia adjunctive therapy in advanced gastric cancer with high-risk of peritonea… Ended

2024-516042-18-00 Gastric Carcinoma 2021-09-08
A Multicenter, Randomized, Double Blind, Parallel Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenan… Ended

2024-513569-38-00 Crohn's Disease 2021-07-09
A Study of the Efficacy and Safety of MK-5475 in Participants with Pulmonary Arterial Hypertension Ended

2022-500877-15-00 Pulmonary arterial hypertension (PAH) in one of the fol 2021-06-25
Study Evaluating the Efficacy and Safety of Belapectin (GR-MD-02) for the Prevention of Esophageal Varices in NASH Cirrhosis Ended

2024-512619-28-00 Esophageal Varices in NASH Cirrhosis 2021-03-08
A Study of Tiragolumab in Combination with Atezolizumab Plus Pemetrexed and Carboplatin/Cisplatin versus Pembrolizumab Plus Pemetrexed and C… Ended

2022-502031-20-00 Non-squamous non-small cell lung cancer (NSCLC) 2020-12-17
A Study to Evaluate the Efficacy and Safety of Dupilumab in Adult Patients with Bullous Pemphigoid Ended

2024-510745-34-00 Bullous Pemphigoid 2020-11-11
Olaparib Plus Pembrolizumab Compared to Chemotherapy Plus Pembrolizumab After Initial Treatment With Chemotherapy Plus Pembrolizumab in Trip… Ended

2022-500418-24-00 Locally Recurrent Inoperable or Metastatic Triple Negat 2020-01-17
The safety and efficacy of Alpha-1 Antitrypsin (AAT) for the prevention of graft‑versus-host disease (GVHD) in patients receiving hematopoie… Ended

2024-511164-92-00 Acute Graft versus host disease 2019-05-17
MIBI-THYR : Value of the combination ultrasonography with Ti-RADS score / dual tracer scintigraphy MIBI-Tc99m/Iodine-123 in the detection of… Ended

2024-516416-22-00 malignancy of thyroid nodules 2019-01-17
ORACLE - Randomized Phase 3 Study evaluating the Efficacy and the Safety of Oral Azacitidine (CC-486) compared to Investigator’s Choice Ther… Ended

2024-519336-16-00 Relapsed or Refractory Angioimmunoblastic T cell Lympho 2018-10-31