Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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Utility of analysis in blood of the evolution of the drug brigatinib for patients with lung cancer with ALK mutations Ended

2024-511317-38-00 ALK+ non-small cell lung cancer 2020-05-04
A trial to learn how camizestrant (AZD9833) works compared to fulvestrant and how safe it is in women with advanced breast cancer who have g… Ended

2023-504974-40-00 Estrogen Receptor Positive HER2 Negative Advanced Breas 2020-04-24
A study of NY-ESO-1 T-cells (GSK3377794) in synovial sarcoma and myxoid/round cell liposarcoma patients Ended

2024-513032-14-00 Synovial sarcoma and Myxoid/Round Cell Liposarcoma (MRC 2020-04-21
A randomized, 2-arm non-comparative phase II study on the efficacy of atezolizumab and Roche bevacizumab (Atezo/Bev) followed by on-demand s… Ended

2024-512682-14-00 Non-resectable hepatocellular carcinoma (HCC) 2020-04-06
ABP - Advancing Brigatinib Properties in anaplastic lymphoma kinase positive nonsmall cell lung cancer (ALK+ NSCLC) patients by deep phenoty… Ended

2024-513947-94-00 locally advanced (stage III) and not suitable for curat 2020-03-30
IMMUWHY Ended

2023-508314-42-00 Advanced stage intrahepatic biliary tract cancer (BTC) 2020-02-27
A phase-2 academic trial testing, in two parallel non-randomized cohorts, the combination of ruxolitinib (JAK1/2 inhibitor) with brentuximab… Ended

2024-520123-83-01 Patients with relapsed or refractory cHL that has not r 2020-02-11
Immune induction strategies to improve response to immune checkpoint blockade in triple negative breast cancer (TNBC) patients: the TONIC-2 … Ended

2024-513217-12-00 Triple negative breast cancer (TNBC) with metastatic di 2020-02-04
Daratumumab combined with Bortezomib, Cyclophosphamide and Dexamethasone for the Treatment of Multiple Myeloma Patients Presenting with Extr… Ended

2024-514963-24-00 Multiple Myeloma patients presenting with extramedullar 2020-02-04
Precision medicine phase II study evaluating the efficacy of a double immunotherapy by Durvalumab and Tremelimumab combined with Olaparib in… Ended

2024-518069-89-00 Patients with solid cancers 2020-02-03
An Open Label Study of JNJ-68284528, Directed Against BCMA in Subjects with Multiple Myeloma Ended

2023-506587-13-00 Multiple Myeloma 2020-01-30
A Randomized Controlled Phase II Clinical Trial with Intradermal IMO-2125 (Tilsotolimod) in pT3-4 cN0M0 Melanoma (Intrim 1 study) Ended

2023-509461-20-00 pT3-4 cN0M0 Melanoma 2020-01-22
An exploratory, multicenter, randomized, open-label with blind evaluation, active controlled study to evaluate the safety and efficacy of Ke… Ended

2024-515667-60-00 Actinic keratosis 2020-01-14
NaDeJ (National Deescalation Study One) Ended

2024-517832-23-00 Human Papillomavirus oropharyngeal squamous cell carcin 2020-01-09
A clinical trial to judge the safety, tolerability and effects on abnormal bone formation of reseach medication AZD 0530 (sarcatinib) in pat… Ended

2024-515186-33-00 Fibrodyplasia Ossificans Progressiva (FOP) 2020-01-08
Olaparib in combination with pembrolizumab in HRRm and HRD positive cancer Ended

2023-503831-17-00 The treatment of participants with HRRm and/or HRD-posi 2019-12-23
A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previo… Ended

2024-511747-25-00 B-cell non-Hodgkin lymphoma (NHL) 2019-12-23
HOVON 156 AML: Treatment for acute myeloid leukemia (AML) or myelodysplastic syndrome with a FLT3 mutation with gilteritinib or midostaurin … Ended

2022-502478-18-00 Acute Myeloid Leukemia (AML) 2019-12-20
RADIANCE Radiochemotherapy +/- Durvalumab for locally-advanced Anal Carcinoma A multicenter, randomized, phase II trial of the German Anal C… Ended

2024-513914-36-00 locally-advanced Anal Carcinoma, Anal cancer stage II a 2019-12-17
Study of Biological Effect in Tumor Samples from Clinical Trial Patients Treated with Ds8201 Ended

2023-508830-33-00 Patients diagnosed with advanced or metastatic cancer t 2019-12-13
ADP-A2M4 in Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma Ended

2024-512847-21-00 Advanced Synovial Sarcoma 2019-12-11
A randomized phase II multicenter study to assess the tolerability and efficacy of the addition of midostaurin to 10-day decitabine in unfit… Ended

2023-503829-18-00 Acute myeloid leukemia 2019-12-05
Prospective Phase-II Trial of induction chemotherapy and chemoradiotherapy plus/minus the PD-L1 antibody durvalumab followed by surgery or d… Ended

2024-513039-26-00 non-small cell lung cancer stages IIIA (N2) and selecte 2019-11-25
Trimodality therapy with or without adjuvant Durvalumab to treat patients with bladder cancer Ended

2024-512502-26-00 Muscle-invasive bladder cancer 2019-11-06