Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A randomized phase II study of second line treatment with liposomal irinotecan and S1 versus liposomal irinotecan and 5-fluorouracil in pati… Ended

2023-509463-24-01 metastatic pancreatic cancer 2019-11-04
Copanlisib and Rituximab in Marginal Zone Lymphoma Patients - A MULTICENTER OPEN LABEL SINGLE-ARM PHASE II STUDY (COUP-1) Ended

2022-500674-34-00 Marginal Zone Lymphoma 2019-11-04
EORTC 1740: Randomized Phase II study of Cisplatin plus Radiotherapy versus Durvalumab plus Radiotherapy followed by Adjuvant Durvalumab ver… Ended

2023-508853-13-00 Oropharyngeal Squamous Cell Carcinoma 2019-10-31
A trial to learn how well osimertinib with savolitinib works in people with non-small cell lung cancer (NSCLC) that has gotten worse after i… Ended

2024-512581-34-00 EGFRm+ and MET+, Locally Advanced or Metastatic Non Sma 2019-10-23
A Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of Ocrelizumab in Children and Adolescents with Rela… Ended

2023-507313-94-00 Relapsing-Remitting Multiple Sclerosis (RRMS) 2019-10-18
Neo-adjuvant chemotherapy combined with Stereotactic Body Radiotherapy to the primary tumour +/- durvalumab (MEDI4736), +/- oleclumab (MEDI9… Ended

2024-511849-19-00 Luminal B Breast Cancer 2019-10-17
Clinical study of ibrutinib and rituximab in untreated marginal zone lymphomas Ended

2023-507886-25-00 Previously untreated and symptomatic patients with hist 2019-09-27
A trial to learn if different cancer treatment combinations are safe and work in people with advanced non-small cell lung cancer that has mu… Ended

2023-504624-25-00 Advanced Non-Small Cell Lung Cancer 2019-09-26
Imaging Perfusion Restrictions from Extracellular Solid Stress - An open-label losartan study Ended

2023-507575-22-00 Glioblastoma - newly diagnosed and recurrent tumors (St 2019-09-25
A phase II trial of MK-3475 (pembrolizumab) in children and young adults with classical Hodgkin lymphoma Ended

2023-504821-38-00 Classical Hodgkin lymphoma in children and young adults 2019-09-19
The Sahlgrenska Anti-VEGF (SAHLVE) Study - a Prospective Randomized Double-blind Comparison of Bevacizumab and Aflibercept in Patients With … Ended

2023-506317-22-00 Neovascular (wet) age-related macular degeneration (AMD 2019-09-18
EFFICACY OF ATEZOLIZUMAB CONCURRENT WITH RADIOTHERAPY IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER Ended

2024-514604-14-00 Muscle-invasive bladder cancer 2019-09-18
AN OPEN-LABEL, MULTICENTER STUDY IN MALE PEDIATRIC PATIENTS WITH CEREBRAL X-LINKED ADRENOLEUKODYSTROPHY (CALD) TO ASSESS THE EFFECTS OF MIN-… Ended

2024-513774-21-00 CEREBRAL X-LINKED ADRENOLEUKODYSTROPHY (CALD) 2019-09-13
Efficacy of first line Bortezomib, Rituximab, Ibrutinib (B-RI) for patients with treatment naive Waldenström’s Macroglobulinemia Ended

2022-500584-12-00 Waldenström’s Macroglobulinemia 2019-09-11
A study to learn if combination pyrimidine nucleosides is safe, how well it works and how it moves through the bloodstream in participants w… Ended

2023-510427-29-00 Thymidine kinase 2 deficiency 2019-09-04
Study assessing the efficacy and safety of durvalumab plus olaparib plus fulvestrant in selected metastatic or locally advanced ER-positive,… Ended

2024-516847-23-00 ER-positive and HER2-negative metastatic or locally adv 2019-08-27
Comparison of therapies before stem cell transplantation in patients with higher risk MDS and oligoblastic AML Ended

2024-515375-35-00 Untreated patients with higher risk MDS and oligoblasti 2019-08-26
Phase II multicenter single arm study to evaluate the efficacy and safety of ibrutinib in combination to rituximab-CHOP followed by ibrutini… Ended

2024-511641-18-00 Diffuse Large B-cell Lymphoma ABC 2019-08-01
EORTC-1537-LYMG: Very early FDG-PET-response adapted targeted therapy for advanced Hodgkin lymphoma: a single-arm phase II study Ended

2023-508478-27-00 Advanced stage Hodgkin Lymphoma 2019-07-30
A trial to learn how well osimertinib with savolitinib works in people with non-small cell lung cancer (NSCLC) that has gotten worse after i… Ended

2024-512564-58-00 EGFRm+ and MET+, Locally Advanced or Metastatic Non Sma 2019-07-05
Liposomal iRInotecan, Carboplatin or oXaliplatin in the first line treatment of esophagogastric cancer: a randomized phase 2 study (LyRICX) Ended

2023-509287-26-00 previously untreated metastatic or locally advanced eso 2019-07-01
OPEN LABEL PHASE 2 STUDY ON THE EFFICACY AND TOLERANCE OF A COMBINATION OF PONATINIB AND 5-AZACITIDINE IN CHRONIC MYELOGENOUS LEUKAEMIA IN A… Ended

2024-516048-24-00 CHRONIC MYELOGENOUS LEUKAEMIA IN ACCELERATED PHASE OR I 2019-06-19
A Phase II study of post-operative palbociclib as an alternative to chemotherapy in older patients with localized breast cancer at high risk… Ended

2023-505223-31-00 Localized ER+ breast cancer 2019-06-14
Trial of dostarlimab (TSR-042) for patients with high-risk locally advanced cervical cancer after chemo-radiation Ended

2023-510268-11-00 Cervical cancer 2019-06-11