Therapeutic Exploratory (Phase II)

3,454 trials 1,368 recruiting

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A Phase 2a study to evaluate the Efficacy, Safety, and Tolerability of MORF-057 in Ulcerative Colitis Ended

2024-516960-27-00 Moderately to severely active ulcerative colitis 2022-07-22
Phase II trial of Pembrolizumab and Olaparib in homologous-recombination deficient (HRD) advanced colorectal cancer (CRC). Ended

2023-509095-42-00 Colorectal cancer 2022-07-14
Effectiveness and Safety of Intra-Dermal Hepatitis B Vaccination after a local application of cream, called IMIQUIMOD, in cirrhotic patients… Ended

2024-514605-61-00 Cirrhotic patients who have already received a HBV vacc 2022-07-08
Phase II non randomized clinical trial of NIVOLUMAB/IPILIMUMAB maintenance following first-line chemotherapy in unresectable locally advance… Ended

2024-514293-46-00 Unresectable locally advanced or metastatic urothelial 2022-07-07
A Phase 2a, Randomized, Placebo-Controlled, Dose-Ranging Study to Evaluate the Safety and Efficacy of PTC518 in Subjects With Huntington’s D… Ended

2023-509835-26-00 Huntington’s Disease 2022-07-06
Epirubicin for the Treatment of Sepsis & Septic Shock Ended

2024-515776-12-00 Patients with sepsis or septic shock, currently hospita 2022-06-30
A Study of MK-1088 as monotherapy and in combination with pembrolizumab in patients with advanced solid tumors Ended

2022-502288-40-00 Treatment of advanced/metastatic solid tumors 2022-06-29
Treprostinil Palmitil Inhalation Powder for Pulmonary Arterial Hypertension Ended

2023-505541-99-00 Pulmonary Arterial Hypertension 2022-06-28
Phase II Study of Fedratinib and Nivolumab Combination in Patients with Myelofibrosis and Resistance or Suboptimal Response to JAK-inhibitor… Ended

2024-513953-64-00 Primary and secondary Myelofibrosis 2022-06-23
A Phase 2 study of durcabtagene autoleucel, B-cell maturation Antigen (BCMA)-directed CAR-T Cells in adult participants with relapsed and re… Ended

2023-507140-37-00 Adult patients with relapsed and refractory multiple my 2022-06-22
Phase 2 Study to Assess Efficacy and Safety of CDR132L in Patients with Reduced Left Ventricular Ejection Fraction (≤45%) After Myocardial I… Ended

2023-507569-24-00 Myocardial Infarction, Acute Heart Failure, Left Sided 2022-06-20
Mechanistic study of the effect of itepekimab on airway inflammation in patients with COPD Ended

2024-512007-39-00 Chronic Obstructive Pulmonary Disease 2022-06-20
PhagoDAIR I : A Pilot, Multicenter, Randomized, Non Comparative, Double-Blind Study of Phage Therapy in Patients with Hip or Knee Prosthetic… Ended

2024-516207-17-00 knee or hip prosthetic joint infection (PJI) due to Sta 2022-06-15
Iron chelation in the prevention of secondary degeneration after stroke Ended

2024-514230-20-00 Stroke 2022-06-08
Evaluation de l’efficacité des alpha-bloquants (Tamsulosine) dans le traitement de la dysurie symptomatique de la sclérose en plaques chez l… Ended

2024-516880-10-00 Patiente atteinte de sclérose en plaques (score EDSS < 2022-06-08
Efficacy and Safety of apraglutide in steroid refractory gastrointestinal acute graft versus host disease. Ended

2023-507960-38-00 Acute graft versus host disease (aGVHD) 2022-06-01
A Phase II Multi-Arm (basket) Trial Investigating the Safety and Efficacy of IO102-IO103 in Combination with Pembrolizumab, as First-line Tr… Ended

2024-511561-10-00 Metastatic Squamous Cell Carcinoma of Head and Neck (SC 2022-05-31
A study to test BI 764198 in people with a type of kidney disease called focal segmental glomerulosclerosis Ended

2024-511706-23-00 Focal segmental glomerulosclerosis 2022-05-31
LAMSA2020: “A phase II randomized study to assess the efficacy on outcome of Venetoclax combined with Cytarabine versus Idarubicin combined… Ended

2022-502392-37-00 elderly patients (> = 60 years) with Acute Myeloid Leuk 2022-05-25
A study to learn how well the treatment combination of finerenone and empagliflozin works and how safe it is compared to each treatment alon… Ended

2023-506981-30-00 Chronic kidney disease in type 2 diabetes mellitus 2022-05-25
A Phase II, randomised, multi-centric, multi-national clinical trial to evaluate the efficacy, tolerability, and safety of a fixed dose comb… Ended

2024-518527-29-00 Polycystic ovary syndrome (PCOS) 2022-05-24
ADJUBIL - A Phase II study of immunotherapy with durvalumab and tremelimumab in combination with capecitabine or without capecitabine in ADJ… Ended

2024-511847-24-00 Biliary tract cancer 2022-05-23
A Study to Evaluate the Efficacy, Safety and Tolerability of HZN-825 in Subjects with Idiopathic Pulmonary Fibrosis Ended

2023-509784-24-00 Idiopathic Pulmonary Fibrosis 2022-05-11
The WILLOW study with enpatoran in SLE and CLE (SCLE and/or DLE) Ended

2024-510872-18-00 Systemic lupus erythematosus (SLE) and cutaneous lupus 2022-05-09