Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Benefit of a flash dose of corticosteroids in digestive surgical oncology: a randomized, double blind, placebo-controlled trial Ended

2024-513728-40-00 scheduled surgery for digestive cancer 2019-07-02
Adjuvant Dynamic marker - Adjusted Personalized Therapy comparing endocrine therapy plus ribociclib versus chemotherapy in intermediate-risk… Ended

2024-515769-32-00 HR+/HER2- early breast cancer 2019-07-02
APIS Apixaban for Intrahepatic Non Cirrhotic Portal Hypertension Ended

2024-514348-95-00 Intrahepatic non-cirrhotic portal hypertension 2019-06-24
Avelumab Program Rollover Study Ended

2024-514274-46-00 Solid Tumors 2019-06-21
A Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis Including Those Who Have a History of Inadequate Respo… Ended

2023-505477-33-00 Psoriatic Arthritis 2019-06-18
A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Cabozantinib (XL184) in Subjects with Radioiodine-Refractory Differentiated… Ended

2024-516478-31-00 progressed thyroid cancer 2019-06-12
A Study of Nivolumab Combined with Ipilimumab Versus Nivolumab Alone in Participants with Advanced Kidney Cancer. Ended

2023-508264-29-00 Advanced Renal Cell Carcinoma with Intermediate- or Poo 2019-06-11
Perioperative Pembrolizumab (MK-3475) Plus Cystectomy or Perioperative Pembrolizumab Plus Enfortumab Vedotin Plus Cystectomy Versus Cystecto… Ended

2023-504932-16-00 Muscle Invasive Bladder Cancer 2019-06-04
A phase III multi-center, randomized, open-label trial to evaluate efficacy and safety of ribociclib with endocrine therapy as adjuvant trea… Ended

2023-510357-42-00 hormone receptor (HR)-positive, HER2-negative, early br 2019-05-22
A Phase 3 Study to compare how effective and safe DCC-2618 is versus sunitinib in patients with GIST who have been treated previously with i… Ended

2024-513277-52-00 Patients with Advanced Gastrointestinal Stromal Tumors 2019-05-20
Safety and efficacy of BL-8040 with G-CSF compared to Placebo with G-CSF for the collection of peripheral blood stem cells for autologous tr… Ended

2024-511953-23-00 Hematopoietic Stem Cell mobilization autologous transpl 2019-05-17
A Randomized, Controlled Phase 3 Study of Cabozantinib (XL184) in Combination with Atezolizumab versus Sorafenib in Subjects with Advanced H… Ended

2024-516479-34-00 Hepatocellular carcinoma 2019-05-17
An open-label extension (OLE) study to evaluate the long-term safety and efficacy of ralinepag in patients with pulmonary arterial hypertens… Ended

2023-509305-68-00 Pulmonary arterial hypertension (PAH) 2019-05-16
A randomized trial that compares Carfilzomib - Lenalidomide - Dexamethasone (KRd) versus Lenalidomide - Dexamethasone (Rd) in new diagnosed … Ended

2024-513396-41-00 PATIENTS WITH NEW DIAGNOSIS MULTIPLE MYELOMA WITH AGE > 2019-05-15
A Study Comparing Risankizumab to Placebo in Subjects with Active Psoriatic Arthritis (PsA) Who Have a History of Inadequate Response to or … Ended

2023-505478-14-00 Psoriatic Arthritis 2019-05-09
A research study to look at how semaglutide compared to placebo affects diabetic eye disease in people with type 2 diabetes (FOCUS) Ended

2023-506827-26-00 While it is well-established that long-term good glycae 2019-05-02
Phase III randomized clinical trial evaluating hyperthermic intraperitoneal chemotherapy (HIPEC) in ovarian cancer considering two different… Ended

2024-514706-31-01 Epithelial ovarian cancer, Fallopian tube ovarian cance 2019-05-02
Study of durvalumab or placebo administered with radiation therapy for patients with early stage non-small cell lung cancer Study of osime… Ended

2024-512667-31-00 Main cohort: Patients with unresected Stage I/II, lymph 2019-04-23
TALAPRO 2: A PHASE 3, RANDOMIZED, DOUBLE BLIND, PLACEBO-CONTROLLED STUDY OF TALAZOPARIB WITH ENZALUTAMIDE IN METASTATIC CASTRATION RESISTANT… Ended

2023-509087-20-00 Metastatic Castration-resistant Prostate Cancer 2019-04-16
An Extension Study to Evaluate the Efficacy and Safety of BMN 111 in Children With Achondroplasia Ended

2023-508864-31-00 Achondroplasia 2019-04-03
This study is being done to test the effectiveness and safety of an investigational drug called acalabrutinib (ACP-196) when taken with alre… Ended

2023-509349-11-00 Previously untreated Chronic Lymphocytic Leukemia Witho 2019-03-22
Phase III randomised trial evaluating chemotherapy early treatment intensification with temozolomide in adults present with a glioblastoma Ended

2022-500451-23-00 Adults with a de novo glioblastoma 2019-03-18
A study to determine the long-term safety and tolerability of oral lucerastat in adult subjects with Fabry disease Ended

2024-513884-20-00 Fabry disease 2019-03-13
A Phase 3 Study of Niraparib in Combination with Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone for Treatment … Ended

2023-503254-12-00 Metastatic Prostate Cancer 2019-03-06