Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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This is a randomized, open-label, multi-center, global, Phase III study to assess the effectiveness and safety of two Immune Therapy drugs, … Ended

2024-512212-21-00 Advanced hepatocellular carcinoma (HCC) 2017-11-28
Efficacy and Safety of 177Lu-edotreotide PRRT in GEP-NET Patients (COMPETE) Ended

2023-510444-21-00 Neuroendocrine tumours of gastroenteric or pancreatic o 2017-11-24
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure with Preserved Ejection Fraction SPIRRIT-HFpEF Ended

2024-517448-79-00 Heart failure with preserved ejection fraction 2017-11-23
Endocrine therapy plus CDK 4/6 inhibition in first- or second-line for hormone receptor positive advanced breast cancer - the SONIA study Ended

2024-516204-42-00 Breast cancer 2017-11-21
Myechild 01: International Randomised Phase III Clinical Trial in Children with Acute Myeloid Leukaemia - Incorporating an Embedded Dose Fin… Ended

2024-516112-21-00 Newly diagnosed acute myeloid leukaemia (AML), high ris 2017-11-20
AAS-Lynch - Assessment of the effect of a daily chemoprevention by aspirin low-dose of new or recurrent colorectal adenomas in patients with… Ended

2024-516601-23-00 Colorectal adenomas 2017-11-14
A Placebo controlled Maintenance and Long-term Extension Study of the Efficacy and Safety of Risankizumab in Participants with Crohn's Disea… Ended

2023-506399-28-00 Crohn's Disease 2017-11-08
L19TNF plus doxorubicin in patients with STS Ended

2024-512789-32-00 Unresectable or metastatic soft tissue sarcoma 2017-10-09
International trial in Philadelphia chromosome-positive acute lymphoblastic leukemia Ended

2024-515499-12-00 Acute lymphoblastic leukemia 2017-10-02
A research study to compare the standard treatment and the study drug (degarelix) in combination with radiotherapy in patients with high-ris… Ended

2024-513450-30-00 very high risk localized or locally advanced prostate c 2017-09-25
DupuytrEn Treatment EffeCtiveness Trial (DETECT) Ended

2024-515110-40-00 Dupuytren's contracture 2017-09-15
Randomized trial of avelumab-cetuximab-Radiotherapy versus standards of care in the head and neck cancers Ended

2024-513964-24-00 Squamous cell carcinoma, previously untreated Stage III 2017-09-14
An Extension and Long-Term Observational Study In Patients Previously Enrolled in a Genentech− and/Or F. Hoffmann-La Roche Ltd−Sponsored Ate… Ended

2023-506186-57-00 Cancer (Future parent protocols may include other cance 2017-09-04
A Phase III double-blind placebo-controlled Randomised Trial of Aspirin on Recurrence and Survival in Colon Cancer Patients Ended

2022-502798-40-00 Patients with resected colon carcinoma 2017-07-31
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Crohn's Disease who Comple… Ended

2023-504951-29-00 Chron's Disease 2017-07-27
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Bendamustine and Rituximab (BR) Alone Versus in Combination wi… Ended

2023-509354-58-00 Mantle Cell Lymphoma 2017-07-14
B-NHL 2013 - Treatment protocol of the NHL-BFM and the NOPHO study groups for mature aggressive B-cell lymphoma and leukemia in children and… Ended

2023-505509-18-00 mature aggressive B-cell lymphoma and leukemia in child 2017-07-12
Endocrine Therapy With or Without Abemaciclib (LY2835219) Following Surgery in Participants With Breast Cancer (monarchE) Ended

2023-509671-17-00 Breast Cancer 2017-07-12
Study with investigational drug PF-06463922 and comparator crizotinib in patients with a specific type of advanced lung cancer Ended

2023-509169-19-00 Advanced ALK positive non-small cell lung cancer 2017-07-11
S1404: A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose Interferon or Ipilimumab to MK-3475 (Pembrolizuma… Ended

2024-516881-12-00 High risk resected melanoma. 2017-07-05
A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Ulcerative Colitis Ended

2024-516199-14-00 Ulcerative Colitis (UC) 2017-04-12
IRinotecan and Oxaliplatin for Colon Cancer in Adjuvant Setting Ended

2024-517489-41-00 High-risk stage III colon cancer 2017-03-27
PAlbociclib and Circulating Tumor DNA for ESR1 Mutation Detection Ended

2024-510704-37-00 ER+/HER2- metastatic breast cancer 2017-03-22
A Clinical trial to compare Acalabrutinib (ACP-196) versus investigator's choice standard treatment with Bendamustine/Rituximab or Idelalisi… Ended

2023-509359-15-00 Relapsed or Refractory Chronic Lymphocytic Leukemia 2017-03-08