Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Comparing two treatment regimen for sinuses tumors and salivary glands: radiotherapy versus chemoradiotherapy Ended

2024-513972-16-00 - Resected tumors of sinuses or salivary glands - Non-o 2017-01-30
Long Term Safety and Efficacy of ABT-494 in Subjects with Ulcerative Colitis. Ended

2023-505699-31-00 Ulcerative Colitis 2017-01-02
Study to Evaluate the Safety and Efficacy of Emtricitabine and Tenofovir Alafenamide (F/TAF) Fixed-Dose Combination Once Daily for Pre-Expos… Ended

2022-501763-40-00 Pre-Exposure Prophylaxis of HIV-1 Infection 2016-12-13
DAHANCA 30: A randomized non-inferiority trial of hypoxia-profile guided hypoxic modification with nimorazole during radiotherapy/chemoradio… Ended

2024-516178-31-00 Head and neck squamous cell carcinoma (HNSCC) 2016-08-24
A Study with an active treatment to Assess the Long-term Safety of Weekly Intravenous Product in Subjects with Pulmonary Emphysema due to Al… Ended

2024-513962-20-00 Pulmonary Emphysema due to Alpha-1-Antitrypsin Deficien 2016-07-14
A Study Comparing Upadacitinib (ABT-494) to Placebo and to Adalimumab in Subjects with Rheumatoid Arthritis who are on a Stable Dose of Meth… Ended

2022-501017-31-00 Rheumatoid arthritis 2016-05-10
CheckMate 274 Ended

2022-500630-29-00 Subjects with High Risk Invasive Urothelial Carcinoma 2016-05-06
Neoadjuvant L19IL2/L19TNF- Pivotal study Ended

2024-515749-40-00 Malignant melanoma of the skin in patients with locally 2016-02-25
Riociguat for treatment of PAH in children from 6 to less than 18 years old Ended

2023-503536-40-00 Pulmonary arterial hypertension (PAH) 2016-02-23
Randomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia (REMAP-CAP) Ended

2023-507889-89-00 Respiratory tract infection 2016-02-19
An Efficacy and Safety Study of JNJ56021927 (ARN509) in High-risk Prostate Cancer Subjects Receiving Primary Radiation Therapy: ATLAS Ended

2023-505246-26-00 High- or very-high risk, localized or locally advanced 2016-01-27
EORTC-1407-GUCG: A randomized phase III trial comparing conventional-dose chemotherapy using paclitaxel, ifosfamide, and cisplatin (TIP) wit… Ended

2024-513509-30-00 Progressive or recurrent germ cell tumor (measurable or 2016-01-11
The Efficacy and Safety of Bimatoprost SR in Patients With Open-angle Glaucoma or Ocular Hypertension Ended

2024-519595-87-00 Ocular hypertension 2015-12-15
A Study of Apalutamide Plus Androgen Deprivation Therapy (ADT) Versus ADT in Participants with mHSPC Ended

2023-508607-20-00 Metastatic Hormone-sensitive Prostate Cancer 2015-11-27
BEVERLY: A randomized open-label phase 3 trial comparing bevacizumab + erlotinib vs erlotinib alone as first line treatment of patients with… Ended

2024-516843-15-00 Non-squamous Non-small Cell Lung Cancer 2015-11-23
Study to Assess Safety and Efficacy of Atezolizumab (MPDL3280A) Compared to Best Supportive Care Following Chemotherapy in Patients With Lun… Ended

2023-505981-26-00 Non−Small Cell Lung Cancer 2015-11-20
RANDOMIZED STUDY COMPARING SENTINEL NODE POLICY TO CURRENT INITIAL STAGING PROTOCOLS IN EARLY STAGE ENDOMETRIAL CARCINOMAS AT INTERMEDIATE A… Ended

2024-513079-42-00 Intermediate-risk, high risk endometrial cancer 2015-11-19
Study to Assess the Long-term Safety of Dupilumab Administered in Participants ≥6 Months to <18 Years of Age With Atopic Dermatitis (AD). Ended

2023-509425-53-00 Atopic Dermatitis 2015-11-09
PALLAS - PALbociclib CoLlaborative Adjuvant Study: A randomized phase III trial of Palbociclib with standard adjuvant endocrine therapy vers… Ended

2024-514841-12-00 To determine whether the addition of palbociclib to adj 2015-10-27
A Randomized multicenter phase III trial comparing enzalutamide vs. a combination of Ra223 and enzalutamide in asymptomatic or mildly sympto… Ended

2023-510453-41-00 Castration resistant prostate cancer patients metastati 2015-10-26
A trial to learn how well osimertinib (AZD9291) works to prevent cancer from coming back after surgery and how safe it is compared to the pl… Ended

2023-506524-82-00 Stage IB-IIIA non-small cell lung carcinoma, with a cen 2015-10-21
eXalt3: Study Comparing X-396 (Ensartinib) to Crizotinib in ALK Positive Non-Small Cell Lung Cancer (NSCLC) Patients Ended

2024-513454-29-00 Non-Small Cell Lung Cancer (NSCLC) 2015-10-15
A Randomized, Multicenter, Open-Label, Non-Inferiority, Phase 3 Study of ACP-196 Versus Ibrutinib in Previously Treated Subjects with High R… Ended

2023-509347-27-00 High Risk Chronic Lymphocytic Leukaemia 2015-09-30
An international study to evaluate the safety and effectiveness of enzalutamide plus leuprolide, enzalutamide alone, and leuprolide alone in… Ended

2024-513521-23-00 Prostate Cancer 2015-08-19