Therapeutic Confirmatory (Phase III)

3,259 trials 1,319 recruiting

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Pembrolizumab/placebo plus chemotherapy as first-line therapy in participants with HER2 negative advanced gastric or GEJ adenocarcinoma Ended

2023-508890-10-00 Gastric and gastric esophageal junction (GEJ) adenocarc 2018-12-05
A phase III trial investigating a gene therapy (AAV-hFIXco-Padua, AMT061), in adult patients with severe or moderately severe haemophilia B,… Ended

2024-510738-42-00 Haemophilia B 2018-12-03
Danish trial of beta blocker treatment after myocardial infarction without reduced ejection fraction (DANBLOCK) Ended

2024-515748-22-01 Myocardinal infarction 2018-12-01
A Phase 3 Study Comparing Daratumumab, VELCADE (bortezomib), Lenalidomide, and Dexamethasone (D-VRd) with VELCADE, Lenalidomide, and Dexamet… Ended

2023-507312-13-00 Multiple Myeloma 2018-11-15
Effectiveness and Safety of Sparsentan as treatment for Primary Focal Segmental Glomerulosclerosis (FSGS) Ended

2023-505494-32-00 Focal segmental glomerulosclerosis (FSGS) 2018-10-15
A study that allows patients from previous studies to continue on the medication. The aim of the study is to determine how safe and effectiv… Ended

2023-508955-37-00 Moderate to severe atopic dermatitis 2018-10-10
Pembrolizumab/Placebo Plus Trastuzumab Plus Chemotherapy in HER2 Positive Advanced Gastric or GEJ Adenocarcinoma Ended

2023-508253-98-00 Gastric or gastroesophageal junction (GEJ) adenocarcino 2018-10-05
Multicenter Extension Study of Oral Ozanimod in patients with Moderately to Severely Active Crohn's Disease Ended

2024-511553-22-00 Moderately to Severely Active Crohn's Disease 2018-10-05
Chemotherapy plus Paclitaxel with Bevacizumab and Atezolizumab versus Chemotherapy plus Paclitaxel and Bevacizumab in Carcinoma of the Cervi… Ended

2024-514179-17-00 Metastatic (stage IVB), Persistent, or Recurrent Carcin 2018-10-02
Multicenter Study of Oral Ozanimod as Maintenance Therapy in patients with Moderately to Severely Active Crohn's Disease Ended

2023-510426-33-00 Moderately to Severely Active Crohn's Disease 2018-09-27
A Study to Evaluate Enfortumab Vedotin Versus (vs) Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelia… Ended

2024-517571-20-00 Locally advanced or metastatic urothelial cancer 2018-09-07
A Phase 1/2/3 Study of the Safety and Efficacy of a Single Dose of Autologous CRISPR-Cas9 Modified CD34+ Human Hematopoietic Stem and Progen… Ended

2024-516894-57-00 Transfusion-dependent β-thalassemia (TDT) 2018-09-07
A Study to Evaluate the Effectiveness and Safety of Ocrelizumab in Patients with Multiple Sclerosis Previously Enrolled in A F. Hoffmann-la … Ended

2023-506543-41-00 Multiple sclerosis (MS) 2018-07-25
Combinations of Cemiplimab (Anti-PD-1 Antibody) and Platinum-based Doublet Chemotherapy in Patients With Lung Cancer Ended

2024-515051-38-00 Non-small Cell Lung Cancer 2018-07-20
Study of durvalumab/placebo + chemoradiation therapy in Patients with Unresectable, Locally Advanced Non-small Cell Lung Cancer Ended

2024-515321-29-00 Patients with Locally Advanced, Unresectable Non-small 2018-06-26
A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy with Atezolizumab or Placebo in Patients with Triple-Negati… Ended

2023-508472-11-00 Patients with early breast cancer 2018-06-13
Trial comparing the continuation of nivolumab and ipilimumab (doublet immunotherapy) to observation after a first 6 months treatment by nivo… Ended

2024-514586-20-01 Non small cell lung cancer 2018-05-02
A RANDOMIZED TRIAL TESTING EARLY VERSUS LATE ONSET OF EPO ALFA TREATMENT IN LOWER RISK MDS WITH NON RBC TRANSFUSION DEPENDENT ANEMIA AND WI… Ended

2024-515356-21-00 Adult subject (18 years of age older) with low or inter 2018-04-17
A Study Evaluating the Efficacy and Safety of Neoadjuvant Treatment with Atezolizumab or Placebo in Combination with Platinum-Based Chemothe… Ended

2023-504209-35-00 Early-Stage Resectable Non-small cell lung cancer (NSCL 2018-04-04
A Study to Evaluate the Efficacy and Safety of Polatuzumab Vedotin in Combination with Rituximab and CHP (R-CHP) Versus Rituximab and CHOP (… Ended

2024-516904-40-00 Previously Untreated Diffuse large B-cell lymphoma (DLB 2018-03-27
A Study of Erdafitinib Compared with Vinflunine or Docetaxel or Pembrolizumab in Subjects with Urothelial Cancer Ended

2023-510296-56-00 Advanced Urothelial Cancer 2018-03-26
Effect of ALlopurinol in addition to hypothermia for hypoxicischemic Brain Injury on Neurocognitive Outcome Ended

2024-511322-31-00 Brain injury termed “hypoxic-ischemic encephalopathy” ( 2018-03-26
CONDYVAC. Efficacy study of the quadrivalent Human Papilloma Virus (HPV) vaccine to prevent recurrence of External Genital Warts (EGW) in pa… Ended

2024-516098-62-00 External Genital Warts (EGW) 2018-01-11
A Phase 3 randomized clinical Study of Pembrolizumab plus epacadostat, pembrolizumab monotherapy, and the EXTREME regimen as first line trea… Ended

2024-512015-47-00 Histologically or cytologically-confirmed Recurrent or 2018-01-09