Digestive System Diseases

633 trials 301 recruiting

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(Peak) A Clinical Study of CGT9486+Sunitinib vs Sunitinib in Patients with Gastrointestinal Stromal Tumors Ended

2022-500637-80-00 gastrointestinal stromal tumor 5 2023-03-28
A Phase 2b Study to Evaluate MORF-057 in Adults with Moderately to Severely Active UC Ended

2022-500953-17-00 Moderately to severely active ulcerative colitis 4 2023-03-23
PRODIGE 81-FFCD 2101-TRIPLET: Study evaluating the benefit of adding Ipilimumab to the combination of Atezolizumab and Bevacizumab in patien… Ended

2022-501217-31-00 Hepatocellular carcinoma 10 2023-03-09
Pembrolizumab and trastuzumab in combination with FLOT in the perioperative treatment of HER2-positive, localized esophagogastric adenocarci… Ended

2024-513610-34-00 HER2-positive, localized esophagogastric adenocarcinoma 4 2023-02-13
Phase 1b study investigating the association of NP137 with Atezolizumab-Bevacizumab combination in first line in unresectable hepatocellular… Ended

2022-500903-38-00 unresectable hepatocellular carcinoma 3 2023-02-09
Multicenter, prospective, double-blind, randomized, three-armed, placebo-controlled study of long-term therapeutic transfer of encapsulated … Ended

2024-517132-22-00 active ulcerative colitis 5 2023-01-26
A randomized, placebo-controlled, double-blind, multi-center trial to assess efficacy and safety of octreotide subcutaneous depot (CAM2029) … Ended

2023-505313-24-00 Polycystic liver disease 10 2022-09-30
Multicentric randomized phase I / II study to evaluate efficacy of trifluridine/tipiracil +/- bevacizumab plus XB2001 (anti-IL-1α True Human… Ended

2024-517024-20-00 Metastatic colorectal cancer patients 9 2022-09-27
A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cho… Ended

2023-505764-11-00 Pruritus associated with Primary Sclerosing Cholangitis 4 2022-06-10
A Study of Evorpacept (ALX148) in Patients with Advanced Gastric Cancer Ended

2023-509406-30-00 Patients with HER2-overexpressing advanced or metastati 10 2022-01-24
Management of moderate POstoperative recurrence in Crohn's disease: a randoMizEd contROLled trial of therapeutic escalation, the POMEROL tri… Ended

2023-508242-18-00 Crohn's disease 6 2021-12-21
Effects of ABX464 during long-term treatment in patients with moderate to severe ulcerative colitis Ended

2023-507974-42-00 Moderate to Severe Ulcerative Colitis 4 2021-12-01
Endoscopic evidence of maintenance of healing with oral NEXIUM in patients 1 to 11 years old with erosive esophagitis. Ended

2023-505454-18-00 Erosive Esophagitis 5 2021-11-24
A Study of Zanidatamab in Combination With Chemotherapy Plus or Minus Tislelizumab in Patients With HER2-positive Advanced or Metastatic Gas… Ended

2023-510319-20-00 Gastroesophageal Adenocarcinoma (GEA) 5 2021-10-21
An Open-Label Extension and long-term efficacy and safety monitoring study of patients with Crohn's disease previously included in the loss … Ended

2024-514326-23-00 Crohn's disease 11 2021-09-10
Long-term safety of apraglutide in short bowel syndrome Ended

2023-510389-28-00 short bowel syndrome 5 2021-06-14
Double blind, multicentric, randomized, placebo-controlled trial, evaluating the efficacy of 24-month of bezafibrate in primary sclerosing c… Ended

2024-511658-28-01 primary sclerosing cholangitis 5 2021-04-06
Research study on whether semaglutide works in people with non-alcoholic steatohepatitis (NASH) Ended

2023-506962-30-00 Non-alcoholic steatohepatitis (NASH) 5 2021-03-29
A Study to compare the efficacy of Risankizumab and Utsekinumab in Subjects with Moderately to Severe Active Crohns Disease Ended

2022-501645-70-00 Crohns Disease 5 2020-11-25
The USTAP CD trial USTekinumab in fistulising Perianal Crohn’s Disease: The USTAP CD study Ended

2023-503380-42-00 patient with moderate to severe Crohn's disease with at 6 2020-11-16
A Long-term Extension Study of Mirikizumab (LY3074828) in Participants With Crohn’s Disease (VIVID-2) Ended

2022-502841-91-00 Crohn’s Disease 5 2020-08-12
A Study of Pembrolizumab (MK-3475) Versus Placebo in Participants With Esophageal Carcinoma Receiving Concurrent Definitive Chemoradiotherap… Ended

2022-501531-16-00 esophageal carcinoma 5 2020-01-24
ELEVATE UC OLE: An Open-Label Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis Ended

2024-515156-21-00 Ulcerative Colitis 5 2020-01-09
CoCroS trial Ended

2024-516002-33-01 Crohn's disease 6 2019-12-23