Digestive System Diseases

633 trials 301 recruiting

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A clinical trial to evaluate the safety and effectiveness of MGL-3196 (resmetirom) in patients with Non-Alcoholic Steatohepatitis (NASH) and… Ended

2024-510626-89-00 Non-Alcoholic Steatohepatitis (NASH) 5 2019-11-18
A Study of the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Ulcerative Colitis Ended

2023-504718-31-00 Moderately to Severely Active Ulcerative Colitis 10 2019-10-19
Evaluation of the Efficacy and the Safety of FOLFIRINOX3 Bevacizumab Treatment in patients with colorectal cancer Ended

2024-515908-39-00 Patients with metastatic colorectal cancer 9 2018-10-29
A Study to Assess the Efficacy and Safety of Risankizumab in Subjects with Ulcerative Colitis Ended

2023-506994-36-00 Ulcerative Colitis 5 2018-10-11
LUCENT-3 Extension Study of Mirikizumab in Ulcerative Colitis Ended

2023-507657-15-00 Ulcerative Colitis 5 2018-09-13
A Placebo controlled Maintenance and Long-term Extension Study of the Efficacy and Safety of Risankizumab in Participants with Crohn's Disea… Ended

2023-506399-28-00 Crohn's Disease 5 2017-11-08
Treatment of peritoneal dissemination in stomach cancer patients with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy; P… Ended

2023-510159-53-01 peritoneal dissemination in stomach cancer patients 4 2017-09-28
A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Subjects with Crohn's Disease who Comple… Ended

2023-504951-29-00 Chron's Disease 5 2017-07-27
STAR-TREC: Can we Save the rectum by watchful waiting or TransAnal surgery following (chemo)Radiotherapy versus Total mesorectal excision fo… Ended

2024-516106-31-00 Early stage colorectal cancer 10 2017-06-16
A Long-Term Extension Study to Evaluate the Safety of Filgotinib in Subjects with Ulcerative Colitis Ended

2024-516199-14-00 Ulcerative Colitis (UC) 5 2017-04-12
Long Term Safety and Efficacy of ABT-494 in Subjects with Ulcerative Colitis. Ended

2023-505699-31-00 Ulcerative Colitis 5 2017-01-02
NEOadjuvant chemotherapy only compared with standard treatment for Locally Advanced Rectal cancer: a randomized phase II trial Ended

2024-517748-76-00 Rectum cancer 9 2016-11-14
PRODIGE 34 - ADAGE: Randomised phase III study evaluating adjuvant chemotherapy after resection of stage III colon adenocarcinoma in patient… Ended

2024-518741-21-00 colon cancer 4 2014-12-23
Extended Criteria Treatment for Liver Metastases With Heavy Tumour Burden Halted

2024-512397-95-00 Colorectal Liver Metastases 4 2026-05-21
Neoadjuvant pembrolizumab with a watch-and-wait strategy for patients with mismatch repair-deficient or microsatellite instability-high (dMM… Halted

2023-509322-22-00 localized colon cancer 4 2025-11-26
NeoART – A phase Ib/II platform trial evaluating the safety and activity of neoadjuvant trastuzumab-deruxtecan containing combination therap… Halted

2024-518841-12-00 HER2 positive resectable esophagogastric adenocarcinoma 9 2025-03-25
Prospective pilot study, assessing imaging performance of 89Zirconium-labelled Girentuximab (89Zr-TLX250) PET-CT in Patients with HepatoCell… Halted

2023-508567-75-00 Gastro-Entero-Pancreatic Neuroendocrine Neoplasms 9 2025-01-29
PUMP-IT RCT: Hepatic arterial infusion PUMP chemotherapy combined with systemic therapy versus systemic therapy alone as Induction Therapy f… Halted

2023-506194-35-00 Colorectal liver metastases 5 2024-11-21
A Phase 2, Double-Blind Study to Assess Dexlansoprazole Delayed-Release Capsules for Healing of EE and Maintenance of Healed EE in Pediatric… Ended

2022-501350-11-00 Erosive Esophagitis 4 2026-04-09
A Randomised, Open-Label, Single-Centre, Study to Evaluate the Bioequivalence of Lanifibranor Ended

2025-524385-18-00 Non-alcoholic steatohepatitis 2 2026-02-11
An open, single arm, single-center, Phase 1 trial investigating the effect of 7-days-repeated administration of linaprazan glurate on the ph… Ended

2024-518194-34-00 Helicobacter pylori infection, GERD 3 2025-11-11
An open-label, randomized, single-dose, two-period, two-treatment, crossover bioequivalence study with GP-IMP-001 in healthy male volunteers… Ended

2025-522921-37-00 inteneded for treatment of - active rheumatoid arthriti 2 2025-10-22
A study to compare the effect of AVT16 and Entyvio® in subjects with moderate to severe active ulcerative colitis. Ended

2023-507705-34-00 Moderate to Severe Active Ulcerative Colitis 5 2025-08-29
A study to Learn How Safe AGMB-129 is in Healthy Adults Taking Multiple Doses of AGMB-129 That Are Increased a Little at a Time Ended

2025-521705-40-00 Fibrostenotic Crohn’s disease 3 2025-07-18