Digestive System Diseases

633 trials 301 recruiting

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Non inferiority study of preoperative chemotherapy without pelvic irradiation for rectal cancer Recruiting

2024-510580-28-00 Middle or low locally advanced resectable rectal carcin 5 2019-06-05
Citalopram for reflux hypersensitivity and functional heartburn Recruiting

2024-517019-57-00 gastro-esophageal reflux disease 6 2018-04-10
Pre-operative capecitabine, oxaliplatin, docetaxel and atezolizumab in gastric cancer (PANDA) Recruiting

2024-519075-26-00 Primary resectable, histologically confirmed gastric or 4 2018-02-27
Stopping anti-TNF treatment in Crohn's and Colitis patients in remission Recruiting

2024-513299-17-00 Ulcerative colitis 6 2017-05-05
Efficacy of adjuvant Imatinib in patients with intermediate-risk gastrointestinal stromal tumor with a high-risk Genomic Grade Index Recruiting

2024-515432-71-00 gastrointestinal stromal tumor 5 2016-09-13
GASTRICHIP TRIAL. D2 resection and HIPEC (Hyperthermic IntraPeritoneal Chemoperfusion) in locally advanced gastric carcinoma. Recruiting

2024-516358-23-00 Gastric adenocarcinoma 5 2013-06-24
A study to investigate the pharmacokinetics and safety of a single dose of duvakitug in healthy adult participants Ended

2025-524617-84-00 Healthy Volunteers 3 2026-04-09
Prospective multicenter randomized controlled double-blind label study of the prophylaxis of recurrent pouchitis after fecal microbiota tran… Ended

2024-517078-52-00 Patients operated with an IPAA for ulcerative colitis w 5 2026-01-19
A Phase 2 Study of Dexlansoprazole Delayed-Release Capsules to Treat Symptomatic Nonerosive Gastroesophageal Reflux Disease in Pediatric Sub… Ended

2022-501349-64-00 Symptomatic nonerosive GERD in paediatric subjects aged 4 2026-01-12
A trial to assess the long-term safety and effectiveness of glepaglutide in patients with short bowel syndrome who have been previously trea… Ended

2025-520775-81-00 Short Bowel Syndrome 5 2025-12-23
DOSE-FINDING CLINICAL TRIAL TO EVALUATE OF INTESTINAL LACTASE ACTIVITY VIA ORAL GAXILOSE ADMINISTRATION IN HEALTHY ADULT VOLUNTEERS Ended

2025-521308-23-00 Hypolactasia 3 2025-11-07
An open label, balanced, randomized, two-treatment, four-period, two-sequence, single-dose, crossover fully replicate bioequivalence study c… Ended

2025-520617-31-00 ulcerative colitis 2 2025-09-12
A Phase 2a Trial to Characterize the Efficacy and Safety of TEV-53408 in Adults with Celiac Disease Ended

2024-517081-42-00 Celiac Disease 4 2025-08-15
A Study of Zolbetuximab Together with Pembrolizumab and Chemotherapy in Adults with Gastric Cancer Ended

2024-519773-19-00 Gastroesophageal Junction Adenocarcinoma 5 2025-07-31
A Study to Compare Risankizumab to Vedolizumab in Adult Subjects With Moderate to Severe Ulcerative Colitis Ended

2024-518998-33-00 Ulcerative Colitis 5 2025-07-23
A Single-Dose Pharmacokinetic Study of Lepodisiran in Participants with Varying Degrees of Liver Impairment and Participants with Normal Liv… Ended

2024-520315-40-00 Normal Hepatic Function and Mild, Moderate, or Severe H 3 2025-07-22
Assessing the safety, tolerability, and effectiveness of crofelemer in people with the intestinal disease Microvillus Inclusion Disease (MVI… Ended

2024-512845-18-00 Microvillous Inclusion Disease (MVID) 4 2025-06-03
A Phase 1 open-label positron emission tomography TRIAL to assess changes in liver uptake of [68Ga]Ga-FAPI-46 following oral administration … Ended

2024-517605-91-00 advanced liver fibrosis 3 2025-05-26
An Open-label study of patients with primary sclerosing cholangitis (PSC) treated with norucholic acid tablets Ended

2024-514292-18-00 Primary Sclerosing Cholangitis (PSC) 5 2025-03-24
Role of Pancreatic Enzyme Replacement Therapy (PERT) (Creon®) in Pancreatic Exocrine Insufficiency (PEI) due to gastrectomy. Ended

2023-507837-18-00 Male and female patients aged ≥ 18 to ≤ 80 after total 6 2025-03-06
A Study to Investigate the Efficacy and Safety of Solrikitug in Adults with Eosinophilic Esophagitis Ended

2024-510849-34-00 Eosinophilic Esophagitis 4 2025-02-04
A Study to Assess the Effectiveness and Safety of RO7790121 for Induction Therapy in Participants with Moderately to Severely Active Ulcerat… Ended

2024-513015-27-00 Moderately to Severely Active Ulcerative Colitis (UC) 5 2025-01-09
A Phase 1b/2a, open-label single ascending doses and multiple ascending doses study in participants with Pi*ZZ AATD Ended

2024-511981-36-00 Alpha-1 antitrypsin deficiency (AATD) 9 2025-01-06
REBALANCE UC : impact of Fecal Microbiota Transplantation in ulcerative colitis:a randomized, sham controlled trial Ended

2024-511863-27-01 Adult patients with ulcerative colitis diagnosed for at 10 2024-12-06