Digestive System Diseases

633 trials 301 recruiting

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A study to investigate the efficacy and safety of brivekimig in adult participants with ulcerative colitis. Recruiting

2024-515241-41-00 Ulcerative Colitis 4 2025-09-10
Clinical study to evaluate the safety and tolerability of long-term treatment with Lecicarbon® in patients with chronic constipation Recruiting

2025-522464-32-00 Treatment of chronic constipation 6 2025-09-09
Saccharomyces boulardii CNCM I-745 in Irritable Bowel Syndrome. Recruiting

2024-520276-10-00 Non-constipated Irritable Bowel Syndrome (IBS) 5 2025-09-04
ALBU-CHIP - Efficacy of human 20% albumin solution + Ringer Lactate versus Ringer Lactate for fluid replacement strategy during cytoreductiv… Recruiting

2024-510943-76-00 Cytoreductive surgery with hyperthermic intraperitoneal 5 2025-09-03
Model-informed precision dosing during infliximab rescue therapy for patients with steroid-refractory acute severe ulcerative colitis: an ex… Recruiting

2023-503509-12-00 Acute severe ulcerative colitis 6 2025-09-01
Safety and efficacy of a human albumin solution with restored structural profile in patients with decompensated cirrhosis Recruiting

2024-515484-54-00 decompensated cirrhosis 4 2025-09-01
ENGIC 01 - COLOSOTO: A single-arm phase II study evaluating 5-fluorouracil plus Panitumumab (anti-EGFR) and Sotorasib (KRAS G12C inhibitor) … Recruiting

2024-514030-20-00 colorectal cancer 4 2025-08-29
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn’s Disease (CD) Recruiting

2024-518914-18-00 Moderate to Severely Active Ulcerative Colitis & Modera 4 2025-08-27
Preoperative Antibiotics for Mild or Moderate Acute Cholecystitis (POMMAC): A Non-inferiority, Open-label, Randomized Controlled Trial – Stu… Recruiting

2024-515958-24-00 Acute cholecystitis 5 2025-08-25
Encapsulated Fecal Microbiota Transfer to Treat Immune Activation in Patients with Cirrhosis and Ascites (TransImmune) – A randomized, doubl… Recruiting

2023-507790-18-00 cirrhosis and ascites 4 2025-08-01
Dapagliflozin in the treatment of decompensated liver cirrhosis: phase IIb randomised, controlled clinical trial Recruiting

2024-511964-95-00 Decompensated liver cirrhosis 4 2025-07-28
SIMBA Recruiting

2024-514740-82-00 Inflammatory Bowel Disease 6 2025-07-16
A phase 1 multi-centre, randomized, single-blind, steady-state study to evaluate pharmacokinetics, pharmacodynamics, safety and tolerability… Recruiting

2024-516197-30-00 Idiopathic or diabetic gastroparesis 3 2025-07-16
Fecal Microbiome Transplantation in Cirrhosis. Randomized, Double-blinded, Placebo-Controlled trial in patients with decompensated cirrhosis… Recruiting

2023-509151-13-00 Decompensated cirrhosis 5 2025-07-04
(PLASTIC-3) [18F]FAPI-PET/CT and Laparoscopy in STagIng advanced gastric Cancer – a multicenter prospective study Recruiting

2024-513255-32-00 Advanced gastric cancer 10 2025-07-03
metastatic colorectal cancer Recruiting

2023-504831-42-00 patient with colorectal cancer with hepatic metastasis 5 2025-06-27
A study to investigate efficacy and safety of SAR441566 in patients with ulcerative colitis Recruiting

2025-520705-12-00 Colitis Ulcerative 4 2025-06-24
Nitroglycerin for Esophageal Food Impaction Recruiting

2023-503983-17-00 Esophageal Food Impaction 4 2025-06-12
Trial of Trastuzumab Deruxtecan (Enhertu®) Plus Chemotherapy Plus or Minus Pembrolizumab versus Chemotherapy Plus Trastuzumab Plus or Minus … Recruiting

2024-513122-27-00 Unresectable, Locally Advanced or Metastatic HER2 posit 5 2025-06-10
Evaluation of the effectiveness and safety of ALKACITRAT® on the treatment of functional dyspepsia Recruiting

2024-512688-30-00 Functional Dyspepsia 6 2025-06-04
Pilot Study of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for Suspected or Proven Nona… Recruiting

2024-511788-27-01 non-alcoholic hepatic steatosisalcoholic hepatic steato 4 2025-06-03
A Study to Compare the Efficacy and Safety of Vedolizumab With and Without Upadacitinib in Adults With Moderately to Severely Active Crohn's… Recruiting

2023-509391-42-00 Chron's Disease 11 2025-06-02
Evaluation of the efficacy and safety of dual biologic and/or small molecule therapy in patients with induction-resistant ulcerative colitis… Recruiting

2023-506628-98-00 Ulcerative colitis 4 2025-05-27
Does placement of a TAP block in patients undergoing laparoscopic inguinal hernia repair have a more efficacious analgesic effect than local… Recruiting

2024-515759-39-00 inguinal hernia 6 2025-05-13