Digestive System Diseases

633 trials 301 recruiting

Filter these 633 trials by phase, country and sponsor.

Open in Search →

Efficacy and Safety of Icotrokinra in Adult and Adolescent Participants with Moderately to Severely Active Ulcerative Colitis Recruiting

2025-521381-10-00 Moderately to Severely Active Ulcerative Colitis 5 2025-12-03
A Study of Long-acting Antibodies Alone and in Combinations for Moderate to Severe Ulcerative Colitis Recruiting

2025-521242-26-00 Moderately to Severely Active Ulcerative Colitis 4 2025-11-27
A Study of LY3537031 in Participants With Normal Liver Function and With Mild, Moderate, or Severe Liver Impairment Recruiting

2025-521947-19-00 Healthy, Hepatic Insufficiency 3 2025-11-19
adIVO Recruiting

2024-520219-42-00 ivosidenib maintenance after SOC adjuvant chemotherapy 10 2025-11-18
IMAGINE 1 Recruiting

2025-522290-11-00 Cholangiocarcinoma, pancreatic cancer, colo-rectal canc 3 2025-11-18
TACTIC : MP0317, A TUMOR TARGETING FAP DEPENDENT CD40 AGONIST DARPIN, IN COMBINATION WITH CHEMOIMMUNOTHERAPY IN FIRST LINE TREATMENT FOR PAT… Recruiting

2024-520029-35-01 ADVANCED BILIARY TRACT CARCINOMA 4 2025-11-17
A First-In-Human, phase I/IIa, open-label trial assessing safety, tolerability, and feasibility of repeated administrations of a novel autol… Recruiting

2025-521227-70-00 Patients with locally advanced or metastatic prostate c 7 2025-11-13
Monocentric, open-label, single-arm, phase I/II clinical trial to evaluate the use of the ONCOGREEN galenic formulation consisting of indocy… Recruiting

2025-521273-14-00 Solid neoplasms of the digestive system (primary and/or 7 2025-11-10
A Study to Assess the Efficacy, Safety, and what the body does to RO7837195 in Participants with Moderately to Severely Active Ulcerative Co… Recruiting

2025-520690-39-00 Moderately to Severely Active Ulcerative Colitis (UC) 4 2025-11-04
A phase 1, Pharmacokinetic Comparison of Vonafexor Acid and Its Lysine Salt (EYP651) and Evaluation of Potential Drug-Drug Interactions. Recruiting

2025-522915-40-00 Healthy volunteers, Impaired renal function and suspect 3 2025-10-28
A study to investigate the efficacy and safety of SAR444336 in adults with microscopic colitis in clinical remission. Recruiting

2024-519495-83-00 Digestive system diseases 4 2025-10-28
Treatment of Gastroesophageal Reflux Disease in Infants- a Randomized Controlled Trial Recruiting

2022-502770-16-00 GERD, Cows' milk allergy 11 2025-10-27
Perioperative hydrocortisone treatment in pancreatoduodenectomy – randomised double-blinded placebo-controlled interventional trial (PD-HYDR… Recruiting

2024-517877-26-00 Pancreatic resection 10 2025-10-16
A randomized, phase 3 multicenter study to confirm the clinical efficacy of linaprazan glurate compared to lansoprazole in participants with… Recruiting

2024-518714-31-00 Erosive esophagitis (EE) due to gastroesophageal reflux 5 2025-10-03
Efficacy and safety of trifluridin/tipiracil in combination with nanoliposomal irinotecan as a second line therapy in patients with cholangi… Recruiting

2024-517330-18-00 advanced, non resectable or metastatic cholangio- or ga 4 2025-10-02
Using lab-grown mini-tumors from pancreatic cancer tissue to predict and improve post-surgery treatment for pancreatic cancer Recruiting

2023-510490-34-00 Patients with functionally resectable pancreatic ductal 4 2025-09-29
Treatment of Bile Acid Diarrhoea with Atorvastatin (BASTA) Recruiting

2025-521856-47-00 Bile acid diarrhoea 11 2025-09-29
Long Term Study of Livmarli Recruiting

2024-516804-40-00 Progressive Familial Intrahepatic Cholestasis 6 2025-09-25
ICEBOAT. A prospective, multi-center, double blind randomized trial of fecal microbiota transplantation (FMT) delivered by capsule versus pl… Recruiting

2024-516099-13-00 Severe Irritable Bowel Syndrome (IBS) 5 2025-09-25
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn’s Disease and Obesity or Overweight:… Recruiting

2024-520210-21-00 Crohn’s Disease 5 2025-09-19
A randomized controlled study to assess the efficacy of topical Sinecathechins used as adjuvant therapy to topical ablative trichloroacetic … Recruiting

2024-519782-21-00 Anal high-grade squamous intraepithelial lesions (HSIL) 6 2025-09-18
Study that aims to investigate how effective and safe the use of a novel modified release tablet formulation of Colesevelam hydrochloride-MM… Recruiting

2024-511993-55-00 bile acid diarrhoea (BAD) 4 2025-09-18
Total Neoadjuvant Therapy for lymph node-positive adenocarcinoma of the OESophagus and oesophagogastric junction: TNT-OES-2 trial Recruiting

2025-521158-40-00 oesophageal cancer 4 2025-09-12
SonoDOCc 2 Recruiting

2023-508500-38-00 Crohn's disease 4 2025-09-12