Digestive System Diseases

633 trials 301 recruiting

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Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects with Moderately to Severely Active Crohn's Dis… Recruiting

2023-509618-12-00 Crohn's Disease (CD) 5 2024-09-11
Study of GS-1427 in Participants With Moderately to Severely Active UC Recruiting

2023-508304-38-00 Ulcerative Colitis (UC) 4 2024-09-10
A Study to Assess Adverse Events and Change in Disease Activity From Intravenous (IV) and Subcutaneous (SC) Lutikizumab in Adult Participant… Recruiting

2023-505678-14-00 Ulcerative Colitis 4 2024-08-19
Efficacy and Safety of Vedolizumab Intravenous in Pediatric Chronic Pouchitis Recruiting

2023-504773-20-00 Active Chronic Pouchitis 5 2024-08-01
A randomised, double-blind, double-dummy, multicentre, phase III, non inferiority trial of an oral mesalazine formulation in patients with a… Recruiting

2023-509606-30-00 Ulcerative colitis 5 2024-07-24
Effect of Saccharomyces boulardii CNCM I-745 on gut microbiota in patients undergoing antibiotic therapy (in the context of erythema migrans… Recruiting

2023-508694-80-01 Patients undergoing antibiotic therapy (in the context 6 2024-06-18
A Study to Learn How Well Dupilumab Works in Adult and Adolescent Participants with Eosinophilic Gastritis with or without Eosinophilic Duod… Recruiting

2022-500795-62-00 Eosinophilic gastritis 4 2024-03-25
ENGIC 02 - PRODIGE 86-FOLFIRINOX SBA- Phase II randomized trial evaluating modified FOLFIRINOX and FOLFOX in the treatment of locally advanc… Recruiting

2023-505486-92-00 Small bowel adenocarcinoma 4 2024-02-09
Ulcerative Colitis: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects with Moderately to Severely Active Ulcerati… Recruiting

2022-501788-41-00 Ulcerative Colitis 5 2023-11-14
A phase 2, multicenter, double-blind, two-arm study of subcutaneous RO7790121 for the treatment of subjects with moderate to severe active c… Recruiting

2023-504265-23-00 Crohn's disease 4 2023-10-23
A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis Recruiting

2022-500345-25-00 Moderately to severely active ulcerative colitis 4 2023-01-16
A phase 2/3, multicenter, randomized, double-blind study to evaluate the efficacy, safety, pharmacokinetics and pharmacodynamics of oral oza… Recruiting

2023-509248-86-00 Moderately to Severely Active Ulcerative Colitis 10 2022-03-11
OPEN LABEL, MAINTENANCE STUDY OF ORAL TOFACITINIB IN CHILDREN WITH MODERATE TO SEVERE ULCERATIVE COLITIS Recruiting

2023-509694-22-00 Ulcerative Colitis (UC) 5 2022-01-26
Ph 3a, linerixibat, Long term safety and tolerability study in pts with PBC Recruiting

2023-503465-33-00 Cholestasis 5 2020-07-03
The Efficacy of Pressurised Intraperitoneal aerosol chemotherapy (PIPAC) combined with CURativE intent minimally invasive radical resection … Recruiting

2024-516194-76-00 Gastric adenocarcinoma 4 2026-05-28
PROlonged Corticosteroid treatment or N-ACetylcysteine for severe alcoholic hepatitis (PROCORNAC) Recruiting

2025-522109-39-00 Alcoholic hepatitis 5 2026-05-22
Is local injection of mesenchymal stem cells after endoscopic dilation safe and does it improve the outcome of intestinal stricture in patie… Recruiting

2024-511034-12-00 Crohn's disease 4 2026-05-20
ORIAMI Recruiting

2023-508249-42-00 Acute mesenteric ischemia 5 2026-05-19
A Single-Dose Pharmacokinetic Study of Eloralintide in Participants with Varying Degrees of Liver Impairment and Participants with Normal Li… Recruiting

2025-523847-36-00 Participants with Mild, Moderate, or Severe Hepatic Imp 3 2026-05-19
Efficacy and tolerability of a simethicone-containing evacuating solution for colorectal cancer screening colonoscopy: a randomized parallel… Recruiting

2025-523748-11-00 colorectal cancer early detection 6 2026-05-18
Dual wavelength fluorescence imaging using fluorescently labelled adalimumab and risankizumab for visualizing drug targeting in Inflammatory… Recruiting

2025-521420-30-00 Inflammatory Bowel Disease (IBD) 9 2026-05-08
PRODIGE 88-CIRCULATE PAC: Phase III multicentric, open-label, randomized study to investigate the efficacy of chemotherapy in patients with … Recruiting

2023-505046-26-00 Colon carcinoma 5 2026-05-07
GRT-1C102: A randomized, double-blind, placebo-controlled dose escalation study to evaluate the safety, tolerability, and pharmacokinetics/p… Recruiting

2025-524328-24-00 Ulcerative colitis 3 2026-05-06
Efficacy of MIrikizumab to achieve traNsmural healing in patiENTs with Crohn’s Disease : EMINENT CD Recruiting

2025-521889-95-00 Crohn's Disease 6 2026-05-04